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SUPRAX
Bacterial infections
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Drug Name:

SUPRAX Rx

Generic Name and Formulations:
Cefixime 400mg; tabs.

Company:
Lupin Pharmaceuticals, Inc.

Therapeutic Use:

Indications for SUPRAX:

Susceptible infections, including pharyngitis, tonsillitis, acute exacerbation of chronic bronchitis; uncomplicated UTIs and cervical or urethral gonorrhea.

Adult:

400mg once daily or 200mg every 12 hrs. Gonorrhea: 400mg once. Infections due to Streptococcus pyogenes: treat for at least 10 days. Renal impairment: adjust dose; see full labeling.

Children:

<6 months: not established. Chew tabs: chew or crush before swallowing. <50kg and 6 months–12yrs: 8mg/kg once daily or 4mg/kg every 12 hrs. >50kg or >12yrs: use adult dose. Otitis media: treat with chew tabs or susp; do not substitute with tabs. Infections due to Streptococcus pyogenes: treat for at least 10 days.

Warnings/Precautions:

Penicillin or other allergy. Renal impairment. History of GI disease. Chew tabs: phenylketonuria. Labor and delivery. Pregnancy (Cat.B). Nursing mothers.

Interactions:

May potentiate carbamazepine, anticoagulants (eg, warfarin) (monitor). May cause false (+) Clinitest, direct Coomb's, nitroprusside test for ketones. Potentiated by probenecid.

See Also:

SUPRAX for ORAL SUSPENSION

SUPRAX CHEWABLE TABLETS

Pharmacological Class:

Cephalosporin.

Adverse Reactions:

Diarrhea, nausea, loose stools, abdominal pain, dyspepsia, vomiting, hypersensitivity reactions, headache, dizziness, seizures, transient renal and hepatic effects; C. difficile-associated diarrhea.

Elimination:

Renal.

Generic Availability:

NO

How Supplied:

Tabs—10, 50, 100; Chew tabs—10, 50; Susp 100mg/5mL—50mL, 75mL, 100mL; 200mg/5mL—25mL, 37.5mL, 50mL, 75mL, 100mL; 500mg/5mL—10mL, 20mL

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