Pediatric Endocrinology

Positive Islet Autoantibody Tests Up Parental Anxiety in T1D

Positive Islet Autoantibody Tests Up Parental Anxiety in T1D

Parents of children with an increased genetic risk for type 1 diabetes had higher level of anxiety.

Efficacy of Biomarker Screening Pathway in Monogenic Diabetes Diagnosis

Efficacy of Biomarker Screening Pathway in Monogenic Diabetes Diagnosis

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Patients with assumed monogenic diabetes were examined using a novel 3-part biomarker screening pathway to detect incorrectly diagnosed cases of type 1 diabetes.

Elevated Adolescent BMI Increases Stroke Risk in Adulthood

Elevated Adolescent BMI Increases Stroke Risk in Adulthood

Over 37,000 men were tracked from ages 8 to 20 to examine the link between adolescent BMI and stroke risk.

Exercise Training Intervention Improves Ventricular Function in Adolescent T1D

Exercise Training Intervention Improves Ventricular Function in Adolescent T1D

Left ventricular function can be improved, but not normalized, in adolescents with type 1 diabetes.

Pediatric Respiratory and Atopic Outcomes With Free Sugar Consumption In Pregnancy

Pediatric Respiratory and Atopic Outcomes With Free Sugar Consumption In Pregnancy

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Data from a UK cohort were used to examine the relationship between maternal sugar intake levels and pediatric respiratory and atopic outcomes.

FDA: Triptorelin Slows Central Precocious Puberty

FDA: Triptorelin Slows Central Precocious Puberty

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Data from a phase 3 clinical trial found that triptorelin achieved positive results in patients age 2 and older with central precocious puberty.

Prevalence of Celiac Disease Varies in Type 1 Diabetes

Prevalence of Celiac Disease Varies in Type 1 Diabetes

Over 3% of study participants with type 1 diabetes also had biopsy-confirmed celiac disease.

Managing Gynecologic Effects of Mental Health Disorders in Adolescents

Managing Gynecologic Effects of Mental Health Disorders in Adolescents

A Committee Opinion noted that mental health disorders may "interfere with adolescents' ability to understand or articulate" health concerns, including menstrual dysfunction and safe sexual behavior.

Decreased BMI z Score in Prepubertal Children With Obesity

Decreased BMI z Score in Prepubertal Children With Obesity

Metformin decreases BMI z score and improves inflammatory parameters in prepubertal children with obesity.

USPSTF Updates Recommendations for Screening Obesity in Children and Adolescents

USPSTF Updates Recommendations for Screening Obesity in Children and Adolescents

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Updates to the US Preventive Services Task Force's recommendations on obesity screening in children and adolescents focus on intensive behavioral interventions.

Mental Health Screenings in Pediatric Patients With Type 1 Diabetes

Mental Health Screenings in Pediatric Patients With Type 1 Diabetes

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Mental health and behavioral screenings should be routine part of care for pediatric patients with diabetes

Obesity Severity Linked to Increased Incidence of Type 2 Diabetes in Children

Obesity Severity Linked to Increased Incidence of Type 2 Diabetes in Children

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American Indian youth with increasingly severe obesity had a significantly higher risk of type 2 diabetes incidence.

Increased Lifetime Risk of Depression In Children With Obesity

Increased Lifetime Risk of Depression In Children With Obesity

Childhood obesity is linked to long-lasting mental health repercussions, including depression in adulthood.

Delivering Preoperative Information: Web-Based vs Conventional Methods

Delivering Preoperative Information: Web-Based vs Conventional Methods

A questionnaire was administered to participants who received preoperative information via either a web-based platform or conventional brochure.

Physical Activity, Sedentary Time and Bone Strength Association in Teens

Physical Activity, Sedentary Time and Bone Strength Association in Teens

Moderate-to-vigorous physical activity was found to be an independent predictor of bone strength in adolescents.

Safety of Cross-Sex Hormones for Transgender Teens

Safety of Cross-Sex Hormones for Transgender Teens

Although increases in hemoglobin and hematocrit levels were recorded, findings support the safety of cross-sex hormones for transgender teens.

Early Puberty, Endocrine Disruptions Noted With Certain Chemical Exposures

Early Puberty, Endocrine Disruptions Noted With Certain Chemical Exposures

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Multiple studies at ENDO 2017 highlighted the dangers linked to both environmental toxin and common household chemical exposure.

Obesity Management Guidelines Overwhelm School Nurses

Obesity Management Guidelines Overwhelm School Nurses

Researchers have identified the barriers to school nurse-led implementation of pediatric obesity management guidelines.

How Does Antenatal Betamethasone Exposure Affect Pediatric Bone Mass?

How Does Antenatal Betamethasone Exposure Affect Pediatric Bone Mass?

The effects of repeat doses of antenatal betamethasone were assessed in 185 eligible pediatric patients.

Insulin Pump Therapy Improves QoL for Adolescents With T2DM

Insulin Pump Therapy Improves QoL for Adolescents With T2DM

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At the end of a 3-month period, adolescents with type 2 diabetes experienced decreased HbA1c levels after using insulin pump therapy.

Diabetic Retinopathy Screening Lacking Among Pediatric Patients

Diabetic Retinopathy Screening Lacking Among Pediatric Patients

Black and Latino youth were less likely to undergo an eye examination for diabetic retinopathy within 6 years of their diagnosis.

Obesity In Girls Linked to Higher Prevalence of Allergies, Atopic Disease

Obesity In Girls Linked to Higher Prevalence of Allergies, Atopic Disease

Girls with obesity were more likely to have a higher allergy score than both normal-weight girls and both obese and normal-weight boys, according

Complication Rates In Adolescents With Type 1 vs Type 2 Diabetes

Complication Rates In Adolescents With Type 1 vs Type 2 Diabetes

Investigators found early signs of kidney disease, retinopathy, arterial stiffness, and hypertension in adolescents with either type 1 or type 2 diabetes.

Rates of Vitamin D Deficiency In Children Increase

Rates of Vitamin D Deficiency In Children Increase

Researchers identified a 15-fold increase in diagnoses of vitamin D deficiency in children between 2008 and 2014.

How Does Antipsychotic Treatment Affect Cardiometabolic Factors in Young Patients?

How Does Antipsychotic Treatment Affect Cardiometabolic Factors in Young Patients?

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Early psychotic symptoms in child or adolescent patients were predictive of elevated BMI and waist circumference scores.

Tight Glycemic Control Not Beneficial in Critically Ill Children

Tight Glycemic Control Not Beneficial in Critically Ill Children

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Keeping blood sugar at lower levels does not confer extra benefit in critically ill infants and children.

Endocrine Society Releases New Pediatric Obesity Guidelines

Endocrine Society Releases New Pediatric Obesity Guidelines

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The evidence-based clinical practice guideline focuses on the prevention and treatment of childhood obesity.

Pediatric Endocrine Society Provides Guidance for Growth Hormone Use in Pediatric Patients

Pediatric Endocrine Society Provides Guidance for Growth Hormone Use in Pediatric Patients

The guidelines focused on idiopathic short stature, growth hormone deficiency, and primary IGF-I deficiency.

Growth Hormone Plus Aromatase Inhibitor in Congenital Adrenal Hyperplasia

Growth Hormone Plus Aromatase Inhibitor in Congenital Adrenal Hyperplasia

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A case report suggested that combination therapy with growth hormone and anastrozole may improve final height in congenital adrenal hyperplasia.

Islet Autoimmunity Risk Not Affected by Infant Formula Type

Islet Autoimmunity Risk Not Affected by Infant Formula Type

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The use of hydrolyzed vs nonhydrolyzed cow's milk-based infant formula does not appear to reduce risk for islet autoimmunity.

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