Pediatric Endocrinology

Growth and Development Differences During Puberty in Children With T1D

Growth and Development Differences During Puberty in Children With T1D

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Study showed gender-discordant metabolic impairment during puberty that was correlated with peak growth velocity in boys, but not in girls.

Repeat Blood Pressure Readings in Children Prevents Unnecessary Follow-up

Repeat Blood Pressure Readings in Children Prevents Unnecessary Follow-up

Only approximately half of pediatric patients with a blood pressure reading ≥95th percentile would be correctly classified based on their initial blood pressure reading.

No Difference in Hydrolyzed vs Conventional Formula Among Infants at Risk for T1D

No Difference in Hydrolyzed vs Conventional Formula Among Infants at Risk for T1D

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Weaning to a hydrolyzed formula did not reduce the risk of type 1 diabetes in children with an increased disease risk.

Trends in CVD, Risk Factors, and Medications in Children With T1D

Trends in CVD, Risk Factors, and Medications in Children With T1D

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Children with T1D had statistically significantly higher prevalence rates of hypertension, hypercholesterolemia, and used more CV medication compared with a matched diabetes-free reference cohort in the period after the onset of diabetes.

Takeout Food May Increase Adverse Health Consequences in Children

Takeout Food May Increase Adverse Health Consequences in Children

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Efforts to reduce takeaway meal consumption in children could have both short-term and long-term health benefits.

Systemic Corticosteroid Use May Increase Fracture Risk in Pediatric Asthma

Systemic Corticosteroid Use May Increase Fracture Risk in Pediatric Asthma

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Increased odds of fractures in pediatric patients with asthma may be associated with systemic corticosteroid use, but not with inhaled corticosteroid use.

Trabecular Bone Morphology Changes May Predict Bone Strength in Girls

Trabecular Bone Morphology Changes May Predict Bone Strength in Girls

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Study investigated the correlations between age and body composition with trabecular morphology in a cohort of healthy girls age 9 to 18.

Alum-Formulated Glutamate Decarboxylase Injections Safe for Prediabetic Children

Alum-Formulated Glutamate Decarboxylase Injections Safe for Prediabetic Children

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Study evaluated the safety and efficacy of autoantigen-specific therapy with alum-formulated glutamate decarboxylase in nondiabetic children with multiple islet autoantibodies.

Pediatric T2D: Lower HbA1c Predicts Better Outcomes With Metformin Monotherapy

Pediatric T2D: Lower HbA1c Predicts Better Outcomes With Metformin Monotherapy

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Findings accentuate the much greater concern regarding clinical outcomes in participants who did not respond to metformin monotherapy.

Hypoglycemia Infrequent in Sulfonylurea-Treated <I>KCNJ11</I>-Related Neonatal Diabetes

Hypoglycemia Infrequent in Sulfonylurea-Treated KCNJ11-Related Neonatal Diabetes

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More research is needed in order to better estimate hypoglycemic frequency in this population, determine the causes of these hypoglycemic episodes, and determine whether it is the sulfonylurea dose or outside factors that play a larger role.

Increased Risk of Type 1 Diabetes in Children With Asthma

Increased Risk of Type 1 Diabetes in Children With Asthma

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A previous diagnosis of asthma increases the risk for subsequent type 1 diabetes by 41%, but a previous diagnosis of type 1 diabetes decreases the risk of subsequent asthma by 18%.

Optimal Dose of Linagliptin Determined for Pediatric T2D

Optimal Dose of Linagliptin Determined for Pediatric T2D

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Study sought to determine the optimal dosing of linagliptin for the treatment of children with type 2 diabetes.

Identifying Risk for Microalbuminuria in Children With Type 1 Diabetes

Identifying Risk for Microalbuminuria in Children With Type 1 Diabetes

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Study sought to evaluate whether baseline autonomic dysfunction was predictive of future increases in urine albumin-creatinine ratio in pediatric patients with type 1 diabetes.

Predictive Glucose Management Systems May Reduce Hypoglycemia in Pediatric Diabetes

Predictive Glucose Management Systems May Reduce Hypoglycemia in Pediatric Diabetes

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A study examined the efficacy and safety of predictive low-glucose management systems for the prevention of hypoglycemia in adolescents with type 1 diabetes.

Effects of Peer Influence in Adolescents With Type 1 Diabetes

Effects of Peer Influence in Adolescents With Type 1 Diabetes

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Study underscores the need to focus on the peer context to understand the functioning of youths with type 1 diabetes.

Thyroid Cancer Less Likely to Progress in Pediatrics, Young Adults

Thyroid Cancer Less Likely to Progress in Pediatrics, Young Adults

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An observational study was conducted by investigators to evaluate the progression of thyroid cancer in young individuals by ultrasonography.

Improving Daily Glucose Monitoring in Adolescents With Incentive-Based Approach

Improving Daily Glucose Monitoring in Adolescents With Incentive-Based Approach

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Incentive-based approaches developed to improve daily adherence to a single behavioral process, such as blood glucose monitoring in adolescents, may not be as effective as multicomponent interventions that address emotional, social, and family processes of diabetes self-management.

Long-Term Risks of Adulthood Obesity Based on Childhood Diagnosis

Long-Term Risks of Adulthood Obesity Based on Childhood Diagnosis

More than half of today's children are expected to be obese at the age of 35 years, with about half of the prevalence occurring during childhood.

Utilizing Trend Arrow Data in CGM Systems to Manage Diabetes in Children

Utilizing Trend Arrow Data in CGM Systems to Manage Diabetes in Children

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Recommendations for utilizing trend arrow data in a mobile continuous glucose monitoring system were recently issued for pediatric patients with type 1 diabetes.

Improved Neonatal Outcomes With Continuous Glucose Monitoring in T1D

Improved Neonatal Outcomes With Continuous Glucose Monitoring in T1D

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Investigators assess maternal hyperglycemia exposure to fetus with neonatal health outcomes.

Childhood Antibiotic Use Not Linked to Islet or Celiac Disease Autoimmunity

Childhood Antibiotic Use Not Linked to Islet or Celiac Disease Autoimmunity

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Islet and celiac disease autoimmunity were defined as a positive test result for islet or tissue transglutaminase autoantibodies at 2 clinic visits at least 3 months apart.

Validation of Ultrasound Risk Stratification Systems for Pediatric Thyroid Nodules

Validation of Ultrasound Risk Stratification Systems for Pediatric Thyroid Nodules

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Investigators assessed the utilization of ATA risk stratification and TI-RADS ultrasound based systems for the assessment of pediatric thyroid nodules.

Low Incidence of ESRD Reported in Childhood-Onset Type 1 Diabetes

Low Incidence of ESRD Reported in Childhood-Onset Type 1 Diabetes

Among patients with childhood-onset type 1 diabetes, there is a very low incidence of end-stage renal disease.

Pancreatic Exocrine Dysfunction Occurs After Islet Autoimmunity in T1D

Pancreatic Exocrine Dysfunction Occurs After Islet Autoimmunity in T1D

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A new study suggests that pancreatic exocrine dysfunction develops after initiation of islet cell autoimmunity, suggesting that exocrine dysfunction is related to diabetes disease pathogenesis itself.

Childhood Obesity Rates Have Flattened in High-Income Countries

Childhood Obesity Rates Have Flattened in High-Income Countries

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There is a need for bridging the disconnect between policies that address underweight and overweight children and adolescents.

Family-Based Therapy Feasible for Overweight, Obese Children and Their Parents

Family-Based Therapy Feasible for Overweight, Obese Children and Their Parents

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Higher-dose and specialized treatment content designed to help families maintain weight-control behaviors following family-based behavioral weight loss treatment enhances weight outcomes.

Improving Vascular Function in Pediatric T1D With Metformin

Improving Vascular Function in Pediatric T1D With Metformin

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Study aimed to determine the effect of metformin on vascular health in children with T1D and above average weight.

Examining the Benefits of Statins, ACE Inhibitors in T1D With Albumin Excretion

Examining the Benefits of Statins, ACE Inhibitors in T1D With Albumin Excretion

Lower incidence of microalbuminuria was noted with the use of ACE inhibitors vs placebo.

Gestational Diabetes Associated With Adiposity, Puberty Onset in Offspring

Gestational Diabetes Associated With Adiposity, Puberty Onset in Offspring

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Researchers assessed the impact of maternal gestational diabetes on insulin resistance and adiposity in adolescent offspring.

Does Serum Vitamin D in Pregnancy Alter T1D Development Risk in Children?

Does Serum Vitamin D in Pregnancy Alter T1D Development Risk in Children?

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Study finds for the first time that during pregnancy the associations between serum 25OHD concentration and 2 single nucleotide polymorphisms are stronger in mothers of children with T1D.

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