Pediatric Endocrinology Archive

Preventing URTI in Children: Does High-Dose Vitamin D Help or Harm?

Preventing URTI in Children: Does High-Dose Vitamin D Help or Harm?

Previous trials suggested that vitamin D supplementation reduces rates of both influenza and other respiratory infections.

Efficacy of Continuous Glucose Monitoring in Preterm Infants

Efficacy of Continuous Glucose Monitoring in Preterm Infants

Although continuous glucose monitoring accuracy and safety in preterm infants has been validated in several studies, this approach has never been studied in neonates.

Infants Hospitalized Most Often for Adrenal Insufficiency, Hypopituitarism

Infants Hospitalized Most Often for Adrenal Insufficiency, Hypopituitarism

Rates of adrenal insufficiency and hypopituitarism were highest during infancy, particularly among females.

Following Approval, Triptorelin 6-Month Injection Now Available to Treat Central Precocious Puberty

Following Approval, Triptorelin 6-Month Injection Now Available to Treat Central Precocious Puberty

Gonadotropin-releasing hormone (GnRH) agonist Triptodur treats central precocious puberty via intramuscular injection.

Central Congenital Hypothyroidism Detection in Neonates

Central Congenital Hypothyroidism Detection in Neonates

Screening programs that measure T4 with reflex TSH in newborns with T4 below a specified cutoff have the potential to detect central congenital hypothyroidism (CCH) and have shown a higher prevalence of CCH than previously thought.

AAP Shares List of 5 Unnecessary Pediatric Tests and Procedures

AAP Shares List of 5 Unnecessary Pediatric Tests and Procedures

The American Academy of Pediatrics urges careful consideration between parents and clinicians prior to ordering these tests.

Predicting Adult MetS, T2D, CV Risks in Childhood

Predicting Adult MetS, T2D, CV Risks in Childhood

BMI measurement alone can also be used to determine associations between childhood and adulthood conditions.

Second-Generation Antipsychotics: Is Diabetes Risk Increased in Children and Adolescents?

Second-Generation Antipsychotics: Is Diabetes Risk Increased in Children and Adolescents?

The study included over 45,000 children using second-generation antipsychotic medications between 2009 and 2013.

Examining the Relationship Between Linear Growth and Bone Accrual in Children and Adolescents

Examining the Relationship Between Linear Growth and Bone Accrual in Children and Adolescents

Height gains "substantially outpaced" bone mineral content gains during childhood, potentially leading to increased fracture risk.

Structural Disease Risk Stratification in Pediatric Patients With Thyroid Cancer

Structural Disease Risk Stratification in Pediatric Patients With Thyroid Cancer

Revised ATA guidelines have led to an increased interest in risk-adopted management strategies for differentiated thyroid cancer.

Metabolic Impact of High Fructose Corn Syrup Restriction in Obese Children

Metabolic Impact of High Fructose Corn Syrup Restriction in Obese Children

Restricting consumption of high fructose corn syrup did not appear to improve insulin resistance in obese children.

ACOG: Guidelines for Teen Contraception Counseling

ACOG: Guidelines for Teen Contraception Counseling

Contraception conversations should take place as early as is appropriate.

Pediatric Alopecia Areata Severity Linked to Serum Vitamin D

Pediatric Alopecia Areata Severity Linked to Serum Vitamin D

Researchers assessed the relationship between serum vitamin D levels, number of patches, and disease severity and duration.

Efficacy of Biomarker Screening Pathway in Monogenic Diabetes Diagnosis

Efficacy of Biomarker Screening Pathway in Monogenic Diabetes Diagnosis

Patients with assumed monogenic diabetes were examined using a novel 3-part biomarker screening pathway to detect incorrectly diagnosed cases of type 1 diabetes.

Elevated Adolescent BMI Increases Stroke Risk in Adulthood

Elevated Adolescent BMI Increases Stroke Risk in Adulthood

Over 37,000 men were tracked from ages 8 to 20 to examine the link between adolescent BMI and stroke risk.

FDA: Triptorelin Slows Central Precocious Puberty

FDA: Triptorelin Slows Central Precocious Puberty

Data from a phase 3 clinical trial found that triptorelin achieved positive results in patients age 2 and older with central precocious puberty.

Managing Gynecologic Effects of Mental Health Disorders in Adolescents

Managing Gynecologic Effects of Mental Health Disorders in Adolescents

A Committee Opinion noted that mental health disorders may "interfere with adolescents' ability to understand or articulate" health concerns, including menstrual dysfunction and safe sexual behavior.

Decreased BMI z Score in Prepubertal Children With Obesity

Decreased BMI z Score in Prepubertal Children With Obesity

Metformin decreases BMI z score and improves inflammatory parameters in prepubertal children with obesity.

USPSTF Updates Recommendations for Screening Obesity in Children and Adolescents

USPSTF Updates Recommendations for Screening Obesity in Children and Adolescents

Updates to the US Preventive Services Task Force's recommendations on obesity screening in children and adolescents focus on intensive behavioral interventions.

Increased Lifetime Risk of Depression In Children With Obesity

Increased Lifetime Risk of Depression In Children With Obesity

Childhood obesity is linked to long-lasting mental health repercussions, including depression in adulthood.

Delivering Preoperative Information: Web-Based vs Conventional Methods

Delivering Preoperative Information: Web-Based vs Conventional Methods

A questionnaire was administered to participants who received preoperative information via either a web-based platform or conventional brochure.

Safety of Cross-Sex Hormones for Transgender Teens

Safety of Cross-Sex Hormones for Transgender Teens

Although increases in hemoglobin and hematocrit levels were recorded, findings support the safety of cross-sex hormones for transgender teens.

How Does Antipsychotic Treatment Affect Cardiometabolic Factors in Young Patients?

How Does Antipsychotic Treatment Affect Cardiometabolic Factors in Young Patients?

Early psychotic symptoms in child or adolescent patients were predictive of elevated BMI and waist circumference scores.

Endocrine Society Releases New Pediatric Obesity Guidelines

Endocrine Society Releases New Pediatric Obesity Guidelines

The evidence-based clinical practice guideline focuses on the prevention and treatment of childhood obesity.

Artificial Sweetener Use Skyrocketed Among US Children

Artificial Sweetener Use Skyrocketed Among US Children

Consumption of foods and beverages with low-calorie sweeteners such as aspartame, sucralose, and saccharin rose 200% among children between 1999 and 2012.

Growth Hormone Does Not Impact Glucose Homeostasis in Turner Syndrome

Growth Hormone Does Not Impact Glucose Homeostasis in Turner Syndrome

Treatment with growth hormone did not affect insulin sensitivity or insulin secretion in girls with Turner syndrome.

Researchers Develop Best Practices for Managing Celiac Disease in Children

Researchers Develop Best Practices for Managing Celiac Disease in Children

Best practices have been developed for managing children with celiac disease, according to a special article published online in Pediatrics.

Beta-Blocker Exposure Tied to Neonatal Hypoglycemia, Bradycardia

Beta-Blocker Exposure Tied to Neonatal Hypoglycemia, Bradycardia

Neonates born to mothers exposed to beta-blockers at the time of delivery have increased risk of neonatal hypoglycemia and bradycardia.

Higher-Than-Expected Rates of Obesity, Hypertension in Teen Athletes

Higher-Than-Expected Rates of Obesity, Hypertension in Teen Athletes

Student-athletes have similar rates of obesity and high blood pressure as non-athletes, according to research published in The Journal of Pediatrics.

Focusing on Health, Rather Than Weight, Better for Adolescents

Focusing on Health, Rather Than Weight, Better for Adolescents

When teenagers are overweight, parents and doctors should encourage a healthy lifestyle rather than focus on the number on the scale.

USPSTF: Insufficient Evidence for Lipid Screening in Children

USPSTF: Insufficient Evidence for Lipid Screening in Children

The US Preventive Services Task Force (USPSTF) has concluded that the evidence is currently insufficient to weigh the balance of benefits and harms of screening for lipid disorders in children and adolescents (aged 20 years or younger).

AAP: Consider 'Female Athlete Triad' During Office Visits

AAP: Consider 'Female Athlete Triad' During Office Visits

Physicians should be aware of the "female athlete triad," which includes amenorrhea, osteoporosis, and disordered eating.

Multi-Interventional Approach Reduces Preventable Pediatric Hypoglycemic Events

Multi-Interventional Approach Reduces Preventable Pediatric Hypoglycemic Events

The intervention combination can reduce preventable hypoglycemic events in hospitalized children receiving insulin.

Abnormal Blood Glucose Associated With Ischemic Stroke Outcomes in Children

Abnormal Blood Glucose Associated With Ischemic Stroke Outcomes in Children

Children who experienced acute arterial ischemic stroke were more likely to experience abnormal blood pressure, high blood glucose, and/or fever.

Case Study of Infant Highlights Importance of Considering Rare Entity in Hypercalcemia Diagnosis

Case Study of Infant Highlights Importance of Considering Rare Entity in Hypercalcemia Diagnosis

An infant presented with fatigue, irritability, and failure to gain weight after prolonged immobilization.

Precocious Puberty More Common in Girls Than Boys

Precocious Puberty More Common in Girls Than Boys

Ovarian cyst and McCune-Albright syndrome were most responsible for the increased risk of non-congenital adrenal hyperplasia gonadotropin-independent precocious puberty.

Care Gaps Identified in Adolescents With Chronic Conditions

Care Gaps Identified in Adolescents With Chronic Conditions

Determinants of care gaps included demographics, disease-related characteristics, health care service use, and patient health behaviors.

BMI, Height in Adolescence Linked to Non-Hodgkin Lymphoma Risk

BMI, Height in Adolescence Linked to Non-Hodgkin Lymphoma Risk

Higher body weight and taller stature during adolescence are associated with increased risk for non-Hodgkin lymphoma.

High Maternal Fish Intake Tied to Increased Risk for Rapid Growth in Infancy

High Maternal Fish Intake Tied to Increased Risk for Rapid Growth in Infancy

High maternal fish intake during pregnancy is associated with elevated risk for rapid growth in infancy, according to a study published in JAMA Pediatrics.

Maternal Vitamin B12, Folate Levels May Affect Offspring's BMI, Heart Rates

Maternal Vitamin B12, Folate Levels May Affect Offspring's BMI, Heart Rates

Mothers' vitamin B12 levels in early pregnancy may impact children's cardiometabolic risk factors at age 5 years.

Dietary Improvements Decreased Metabolic Syndrome Severity in Adolescents

Dietary Improvements Decreased Metabolic Syndrome Severity in Adolescents

Metabolic syndrome severity has decreased among adolescents from 1999 and 2012.

Undescended Testis Diagnosed in About 2% of Boys

Undescended Testis Diagnosed in About 2% of Boys

One in 50 boys are born with undescended testis, with two-thirds having no report of corrective surgery, researchers wrote in Pediatrics.

Standing Desks in Classrooms May Benefit Children

Standing Desks in Classrooms May Benefit Children

Standing desks in classrooms decreased children's sitting time by about 1 hour each day, according to a review published in Pediatrics.

Infant Gut Microbiome Affected by Delivery, Feeding Methods

Infant Gut Microbiome Affected by Delivery, Feeding Methods

A vaginal birth and breastfeeding make a notable difference in the bacterial composition of an infant's gut.

Early Development in Children May Not Always Indicate Precocious Puberty

Early Development in Children May Not Always Indicate Precocious Puberty

Children who develop certain signs of puberty at an early age are commonly referred to specialists for an evaluation, but this is often unnecessary.

AAP Recommends Screening for Cholesterol, Depression, HIV in All Children

AAP Recommends Screening for Cholesterol, Depression, HIV in All Children

American Academy of Pediatrics guidelines reflect concerns about obesity, suicide, and more.

Review Discusses PCOS Diagnosis, Treatment in Adolescents

Review Discusses PCOS Diagnosis, Treatment in Adolescents

Hyperandrogenic anovulation for more than 2 years distinguishes PCOS from physiologic anovulation, according to the review.

High Prenatal Exposure to Perfluorooctanoic Tied to Excess Weight in Children

High Prenatal Exposure to Perfluorooctanoic Tied to Excess Weight in Children

The researchers noted that more studies are needed to show cause-and-effect relationship.

Reducing Sugar Intake Can Rapidly Improve Metabolic Health in Children

Reducing Sugar Intake Can Rapidly Improve Metabolic Health in Children

Though calories remained same, obese children saw better BP, cholesterol, blood glucose levels

Later Bedtime for Adolescents May Increase Weight Gain Over Time

Later Bedtime for Adolescents May Increase Weight Gain Over Time

Teens with a later weekday bedtime more likely to experience increased BMI over time.

Metformin Linked to Increased Height in Children, Teens

Metformin Linked to Increased Height in Children, Teens

In larger doses, the diabetes drug may increase height in children and adolescents.

Walking Breaks Improve Blood Sugar in Children

Walking Breaks Improve Blood Sugar in Children

Walking breaks that interrupt sedentary behavior may help prevent obesity, diabetes.

HOMA-IR Affected by Sleep in Overweight, Obese Adolescents

HOMA-IR Affected by Sleep in Overweight, Obese Adolescents

Significant contributors include BMI z-score, age, pubertal stage, total sleep time and sleep efficiency.

Alcohol, Marijuana Use Common in Teens with Chronic Illnesses

Alcohol, Marijuana Use Common in Teens with Chronic Illnesses

Four out of 10 high school students with medical conditions used one or both in past year

Hypoglycemia at Birth Tied to Lower School Scores

Hypoglycemia at Birth Tied to Lower School Scores

However, evidence is to preliminary to recommend routine screening.

Long-Term Treatment Outcomes to Soon Be Studied in Transgender Youth

Long-Term Treatment Outcomes to Soon Be Studied in Transgender Youth

The first study in the United States to investigate the long-term outcomes of medical treatment for transgender youth is set to begin in the near future.

Contraception Use Less Likely Among Obese Teen Girls

Contraception Use Less Likely Among Obese Teen Girls

There was no difference in frequency of sex according to weight status among 18- to 19-year-old girls.

Longer-Term Histrelin Safe, Effective for Central Precocious Puberty

Longer-Term Histrelin Safe, Effective for Central Precocious Puberty

Long-term treatment with the histrelin implant safely and effectively sustained gonadotropin suppression and improved predicted adult height in central precocious puberty.

Ferring to Launch Pediatric Endo Products Zomacton and Zoma-Jet Soon

Ferring to Launch Pediatric Endo Products Zomacton and Zoma-Jet Soon

Ferring announced that the FDA has approved the name changes of its newly acquired products to be marketed as Zomacton (somatropin [rDNA origin]; formerly Tev-Tropin) for injection, and the needle-free delivery system as Zoma-Jet (formerly Tjet).

Melatonin May Have Lasting Endocrine Effects in Children

Melatonin May Have Lasting Endocrine Effects in Children

Animal research suggests that melatonin use in children with sleep disorders may affect the reproductive organs and endocrine system.

Plant-Based Diet May Cut Cardiovascular Risk in Obese Children

Plant-Based Diet May Cut Cardiovascular Risk in Obese Children

Significant improvements were seen in metabolic parameters, including BMI, cholesterol levels and insulin resistance.

Parents May Encourage Exercise With Menu Calorie Counts

Parents May Encourage Exercise With Menu Calorie Counts

Info about minutes or miles of activity required to burn off calories may be most helpful.

How Does Pizza Impact Children's Diets?

How Does Pizza Impact Children's Diets?

When pizza is consumed, it makes up more than 20% of children's daily intake of calories.

Genetic Cause of Gigantism Explored

Genetic Cause of Gigantism Explored

Researchers have discovered a single gene in a region of the X chromosome that may cause excessive growth in children.

Colleges Need to Improve Chronic Illness Care for Students

Colleges Need to Improve Chronic Illness Care for Students

Only half of college campus clinics feel they can handle diabetes care, and many don't reach out to students about needs.

Beloranib to Be Tested in Prader-Willi Syndrome

Beloranib to Be Tested in Prader-Willi Syndrome

Beloranib for treatment of Prader-Willi syndrome enters phase 3 trial.

Genes Strongly Influence Height

Genes Strongly Influence Height

New study doubles the number of gene regions linked to height.

Early Obesity Ups Risk for Bullying Involvement

Early Obesity Ups Risk for Bullying Involvement

Obese children in early primary school are significantly more likely to be involved with bullying, both as victim and perpetrator.

Parents Less Likely to Perceive Child Obesity

Parents Less Likely to Perceive Child Obesity

Overweight or obese children are now less likely to be perceived correctly by their parents vs. 10 years ago.

Growth Hormone Therapy May Worsen Depression in Children

Growth Hormone Therapy May Worsen Depression in Children

Growth hormone treatment may increase depression and withdrawal symptoms in children with growth hormone deficiency or idiopathic short stature.

Puberty in Girls Affected by 'Imprinted Genes'

Puberty in Girls Affected by 'Imprinted Genes'

A subset of genes related to parental inheritance may affect timing of puberty in girls.

More Teens Using Growth Hormone

More Teens Using Growth Hormone

The percentage of teens using human growth hormone has more than doubled since 2012.

Inhaled Corticosteroids Affect Children's Growth

Inhaled Corticosteroids Affect Children's Growth

Inhaled corticosteroids use is associated with a significant reduction in linear growth velocity.

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