Osteoporosis

Long-Term Safety of Denosumab in Postmenopausal Osteoperosis

Long-Term Safety of Denosumab in Postmenopausal Osteoperosis

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The most common adverse events associated with long-term denosumab use were back, musculoskeletal, or extremity pain, hypercholesterolemia, and cystis.

Osteoporosis Care Quality Most Consistently Predicted By Primary Care

Osteoporosis Care Quality Most Consistently Predicted By Primary Care

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The most important predictor for use of osteoporosis care was receiving primary care services within 6 months following hip fracture.

DXA-Visceral Adipose Tissue Measurements in Atherosclerotic CVD Risk Assessment

DXA-Visceral Adipose Tissue Measurements in Atherosclerotic CVD Risk Assessment

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Neither DXA-visceral adipose tissue nor android-gynoid fat mass ratios were associated with atherosclerotic cardiovascular disease events.

Leg Positioning During Lumbar Spine DXA

Leg Positioning During Lumbar Spine DXA

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Researchers evaluated trabecular bone scores in more than 100 women during either "legs up" or "legs down" dual energy x-ray absorptiometry scans.

Bone Age in Children as Assessed by Dual-Energy X-Ray and Radiography

Bone Age in Children as Assessed by Dual-Energy X-Ray and Radiography

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Using dual-energy X-ray absorptiometry for bone age assessment complements traditional radiologic assessment.

Accuracy of Trabecular Bone Score to Assess Fragility Fracture Risk in T1D

Accuracy of Trabecular Bone Score to Assess Fragility Fracture Risk in T1D

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Fragility fracture risk increased with older age and decreased with higher bone mineral density in patients with type 1 diabetes.

Is DXA Required to Diagnose Vertebral Fracture in Patients With Low BMD?

Is DXA Required to Diagnose Vertebral Fracture in Patients With Low BMD?

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Researchers compared the efficacy of dual-energy x-ray absorptiometry with lateral x-ray in assessing vertebral fractures.

TeleECHO Clinic Improves Physician Confidence in Osteoporosis Care

TeleECHO Clinic Improves Physician Confidence in Osteoporosis Care

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The Bone Health TeleECHO Clinic helps telementor healthcare professionals and improves osteoporosis care in underserved communities.

Testosterone Increases Lumbar Spine Volumetric Trabecular BMD in Older Men

Testosterone Increases Lumbar Spine Volumetric Trabecular BMD in Older Men

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Testosterone treatment improved both bone mineral density and strength in older men.

Anti-fracture Therapy Effectively Prevents Bone Loss in Women Post-Critical Illness

Anti-fracture Therapy Effectively Prevents Bone Loss in Women Post-Critical Illness

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Researchers found that female patients recovering from critical illness respond better to anti-fracture therapy for bone mineral density loss prevention compared with men.

Do Bone Turnover Markers Predict Vertebral Fracture Risk Post-Alendronate Discontinuation?

Do Bone Turnover Markers Predict Vertebral Fracture Risk Post-Alendronate Discontinuation?

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Study examines the predictive value for vertebral fractures of bone mineral density and bone turnover markers after a 5-year drug holiday.

Bisphosphonate Drug Holiday Increases Fracture Risk in Postmenopausal Women

Bisphosphonate Drug Holiday Increases Fracture Risk in Postmenopausal Women

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The risk of developing fracture in postmenopausal women with osteoporosis who discontinued bisphosphonate therapy was evaluated in a retrospective study.

Nonvertebral Fracture Risk After Roux-en-Y Gastric Bypass

Nonvertebral Fracture Risk After Roux-en-Y Gastric Bypass

Researchers examined the nonvertebral fracture risk in adults with obesity who underwent Roux-en-Y gastric bypass vs adjustable gastric banding.

Older Men With Low Total, Bioavailable Testosterone at Increased Risk for Falls

Older Men With Low Total, Bioavailable Testosterone at Increased Risk for Falls

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Incident falls were linked with total testosterone and bioavailable levels of testosterone after adjusting for age and prevalent falls.

Oral Bisphosphonate Prescription Trends Shifted After 2008 Recommendations

Oral Bisphosphonate Prescription Trends Shifted After 2008 Recommendations

Two distinct time trends were observed in initiation of oral bisphosphonates in women after the 2008 updated osteoporosis treatment guidelines.

Heart Disease, Osteoporosis Risks Up in Young Thyroid Cancer Survivors

Heart Disease, Osteoporosis Risks Up in Young Thyroid Cancer Survivors

Younger survivors of thyroid cancer are at increased risk for certain types of health problems later in life.

Fracture Risk in Psoriatic Arthritis, Psoriasis Examined

Fracture Risk in Psoriatic Arthritis, Psoriasis Examined

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Patients with psoriatic arthritis or psoriasis had an increased prevalence of osteoporosis risk factors.

FDA Clears Point-of-Care Device for Diagnosing Osteoporosis

FDA Clears Point-of-Care Device for Diagnosing Osteoporosis

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Bone Index announced that the Food and Drug Administration (FDA) has granted clearance for the second generation Bindex device model to aid in the diagnosis of osteoporosis.

Bone Density Linked to Vascular Calcification in ESRD

Bone Density Linked to Vascular Calcification in ESRD

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A prospective cohort study in 66 patients with end-stage renal disease was conducted to determine the link between renal and coronary heart diseases.

Hip Fracture Risk in Type 2 Diabetes

Hip Fracture Risk in Type 2 Diabetes

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The association between risk for hip fracture and diabetes was attenuated after accounting for mortality risk.

Long-Term DPP-4 Inhibitor Use Not Associated With Fracture Risk in Type 2 Diabetes

Long-Term DPP-4 Inhibitor Use Not Associated With Fracture Risk in Type 2 Diabetes

For patients with type 2 diabetes, long-term use of dipeptidyl peptidase-4 (DPP-4) inhibitors is not associated with fracture risk.

VIDEO: Clinical Trial Results for Abaloparatide

Lorraine Fitzpatrick, MD, discusses updated results from the ACTIVE phase 3 clinical trial.

The Handoff: Your Week in Endocrinology - 11/25/16

In this week's Handoff, read more about recent FDA approvals, food banks' efforts to improve the healthiness of their donations, and more.

Does Antihypertensive Medication Class Affect Fracture Risk?

Does Antihypertensive Medication Class Affect Fracture Risk?

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Researchers compared 3 classes of antihypertensive medication to determine hip and pelvic fracture risk in users vs nonusers.

Bone Health Improved With Menopausal Hormone Therapy

Bone Health Improved With Menopausal Hormone Therapy

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The use of menopausal hormone therapy was associated with improved bone mineral density and better bone microarchitecture.

New Osteoporosis Treatment Options on the Horizon

Nancy E. Lane, MD, professor of medicine, at the University of California at Davis School of Medicine, discusses results from the phase 3 ACTIVE trial.

Bone Density Lower Among Heavy Cannabis Users

Bone Density Lower Among Heavy Cannabis Users

Heavy cannabis users have lower bone density compared to cigarette smokers.

Benefits, Drawbacks of Calorie Restriction in Postmenopausal Women

Benefits, Drawbacks of Calorie Restriction in Postmenopausal Women

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Calorie restriction has been shown to increase longevity, but it may also have adverse effects on bone health in postmenopausal women.

Bone Mineral Density Linked to Concentrations of 25(OH)D in Summer

Bone Mineral Density Linked to Concentrations of 25(OH)D in Summer

Summer levels of serum 25-hydroxyvitamin D are associated with bone mineral density of the total hip.

AACE/ACE Updates Postmenopausal Osteoporosis Management Guidelines

AACE/ACE Updates Postmenopausal Osteoporosis Management Guidelines

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The American Association of Clinical Endocrinologists (AACE) and the American College of Endocrinology (ACE) announced the publication of new clinical guidelines and an accompanying algorithm to help physicians and other health care professionals with the diagnosis, fracture risk assessment, and treatment of postmenopausal osteoporosis.

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