Gastric Bypass Associated With Improved Long-Term Survival in Patients Older Than 35

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Gastric bypass has been associated with improved long-term survival in patients aged older than 35.
Gastric bypass has been associated with improved long-term survival in patients aged older than 35.

(HealthDay News) — Gastric bypass surgery is associated with improved long-term survival for patients at all ages older 35 years, according to a study published in JAMA Surgery.

Lance E. Davidson, PhD, from Brigham Young University in Provo, Utah, and colleagues categorized patients undergoing gastric bypass surgery according to age as younger than 35 years, 35 through 44 years, 45 through 54 years, and 55 through 74 years. Data were included for 7925 patients undergoing gastric bypass surgery and 7925 matched, severely obese individuals who did not undergo surgery.

The researchers found that, compared with controls who did not undergo surgery, adjusted all-cause mortality was lower for patients aged 35 through 44, 45 through 54, and 55 through 74 years (hazard ratios [HRs]=0.54 [95% CI, 0.38-0.77], 0.43 [95% CI, 0.30-0.62], and 0.50 [95% CI, 0.31-0.79], respectively; all P<.003) who underwent gastric bypass. 

Patients younger than 35 not have lower mortality (HR=1.22; 95% CI, 0.82-1.81; P=.34). The lack of benefit for patients aged younger than 35 years was mainly attributable to a significantly higher number of externally caused deaths, especially among women.

"Gastric bypass surgery is protective against mortality even for older patients and also reduces the age-related increase in mortality observed in severely obese individuals not undergoing surgery," the researchers wrote.

One author disclosed financial ties to the law firm Gjording Fouser.

Reference

  1. Davidson LE, Adams TD, Kim J, et al. Association of Patient Age at Gastric Bypass Surgery With Long-term All-Cause and Cause-Specific Mortality. JAMA Surg. 2016. doi:10.1001/jamasurg.2015.5501.
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