Psychiatric diagnoses may not be a contraindication to weight loss surgery.
Consumers with obesity report favoring taste and value rather than health and nutrition.
Increased obesity for men, women living in medium, small versus large metropolitan statistical areas
Investigators conducted a retrospective observational study to assess the impact of psychostimulant medication on BMI and height in a group of children and adolescents with ADHD.
Researchers assessed the effect of formula supplementation vs breastfeeding on the gut microbiome and risk of infant overweight.
The prevalence of obesity is higher among those living in non-metropolitan counties versus metropolitan counties.
Many working Americans obtain food and beverages from work, and these foods often do not align with dietary guidelines.
The researchers found that on a given day, 85 percent of infants and toddlers had any consumption of added sugar.
Researchers assessed current patterns of physical activity and duration among adolescents and young adults, as well as the direction and magnitude of associations between physical activity and income, race/ethnicity, and sex among participants in the National Health and Nutrition Examination Survey.
Increased adherence to healthy dietary patterns could result in health care savings from improved health outcomes.
Regardless of long-term metabolic health maintenance, obesity remains a risk factor for cardiovascular disease.
If current trends continue, one-third of children and one-half of adolescents will be obese or overweight by 2030.
Specifically, the new labeling includes updated data on the global rate of occurrence related to these adverse events.
Body mass index and body fat distribution may influence smoking behaviors.
Investigators assessed the effects of diazoxide on lipid and glucose metabolism in obese men with diabetes.
Physical activity modifies the association between the body mass index genetic risk score and BMI.
Investigators examined changes in weight from childhood to early adulthood and the risk for developing type 2 diabetes.
Endocrinologist Kevin M. Pantalone, DO, and psychiatrist Christian Kohler, MD, discuss the risk associated with the use of antipsychotic medications in individuals with type 2 diabetes.
Severe obesity is associated with more rapid progression of disability in rheumatoid arthritis.
Baseline obesity is associated with an increased risk for late-life mobility limitations in women undergoing joint replacement for OA.
In 2014, health care provider counseling for weight loss for adults with arthritis and overweight or obesity was 45.5 percent, up 10.4 percent from 2002.
Eesearchers found that baseline metabolically healthy obesity was not significantly associated with incident cardiovascular disease, compared with metabolically healthy normal weight.
Maternal caffeine intake >200 mg/day during pregnancy was associated with high weight gain velocity beginning from the first months of life and higher BMI throughout childhood.
Severely obese rheumatoid arthritis patients also had worse disability at baseline than overweight patients.
Researchers sought to determine the predictive value of tibiofemoral MRI, patellofemoral MRI, and KLG1 for the incidence of clinical or radiographic knee OA.
Based on findings from a systematic review of the literature, recommendations have been developed for improving the evidence for natural experiments in obesity.
Improved research methods needed to determine effectiveness of anti-obesity public health initiatives
Researchers found that amongst nearly 300 studies reporting the impact of policies, programs, or changes in built environment on controlling and preventing obesity, most natural experiments had high risk of bias and poor handling of dropouts and withdrawals.
Researchers assessed the weight stigma experiences of 1,513 men, examining the characteristics of men who experienced weight stigma versus men who did not.
Targeted diabetes screening based only on age and weight criteria will identify approximately half of US adults with dysglycemia.
Results suggest that circadian preference and meal timing are novel and possibly modifiable risk factors for obesity in type 2 diabetes.
A soda tax does influence daily consumption of regular soda, energy drinks, and bottled water.
Further clinical trials are needed to explore the potential beneficial effect of vitamin D supplementation, via fortified foods and/or dietary supplements, on insulin resistance, and possibly on weight management.
Ethnicity,race, markers of insulin resistance, and genetic factors might help identify obese youth at risk for developing fatty liver.
Researchers examined the relationship between early to mid-childhood adiposity measures and mid-childhood alanine aminotransferase levels.
For overweight or obese adults with T2D, a long-term weight loss intervention is associated with a reduction in long-term disability.
Parents and healthcare workers should carefully consider the risk for obesity in infants born to women with diabetes, especially infants born large for gestational age, and should initiate preventive measures where possible.
In obese subjects with and without type 2 diabetes, oxyntomodulin significantly augments glucose-dependent insulin secretion.
Researchers conducted secondary analysis of data from a multicenter study of 5580 women from 11 Latin America countries in order to assess the association between waist-to-height ratio and anxiety.
Compared to men who were never overweight, those overweight at age 7 who returned to a normal body mass index by age 13 had no increased risk for developing type 2 diabetes.
The Copenhagen Co-morbidity in HIV Infection (COCOMO) study assessed the association between risk factors for cardiovascular disease and HIV infection.
Current care should encourage women to plan to breastfeed, provide corrective information for specific beliefs, and address issues relating to body image and social knowledge.
The findings from a national sample underscore the importance of developing policies and programs that reduce the prevalence of obesity.
Changes in serum insulin and homeostatic model assessment of insulin resistance and beta cell function were significantly greater compared to the control diet
The J-shaped correlation seen for body mass index with cardiovascular disease risk is susceptible to confounding due to pre-existing comorbidities.
Researchers conducted a comprehensive narrative review to examine the correlation of the obesity pandemic with appearance of cancers in young adults under age 50.
Metabolites could be mediators in the connection between gut microbiota and obesity and points to potential future opportunities for targeting the gut microbiota in the prevention of obesity.
Change in body mass index to overweight during puberty significantly increases men's risk of heart failure later in life.
Of various interventions used in nonclinical settings for the prevention of childhood overweight and obesity, school-based programs that combine nutrition and exercise and include a home-based component appear to be the most effective approaches.
For men with metastatic melanoma treated with targeted or immune therapy, obesity is associated with improved survival.
For patients with chronic hepatitis B virus, body mass index is significantly associated with increased risk of hepatocellular carcinoma, with the risk more pronounced for women than men.
Following the success of this preliminary safety and feasibility study, more patients are being recruited for a larger clinical trial of the procedure to test the efficacy and durability of the procedure.
Given the high risk for metabolic disorder and type 2 diabetes, clinicians should select psychotropic medications carefully and monitor metabolic conditions regularly in their patients with serious mental illness.
For adults, but not youth, there was an increase in the prevalence of obesity in decade between 2007-2008 and 2015-2016.
Researchers evaluated the association between low maternal vitamin D status in early pregnancy and the likelihood of childhood obesity in the offspring.
Physicians should be aware that the benefit of menopausal hormone therapy (MHT) on body composition might rapidly disappear after its withdrawal and strongly encourage women to optimize nutrition and increase physical activity when stopping MHT.
Calorie restriction over 2 years is associated with considerable weight loss, and with lower than expected energy expenditure.
Researchers compared glycemic control in cohorts of severely obese adolescents with type 2 diabetes undergoing medical and surgical interventions.
Results comparing the prevalence of obesity amongst adolescents with the rate of bariatric surgeries were presented at ENDO 2018.
In combination with dietary and physical activity counseling, all semaglutide doses from 0.05-0.4 mg daily were tolerated and resulted in dose-related reductions in body weight among people with obesity without diabetes.
In people with obesity and type 2 diabetes, a meal schedule that includes a high-energy breakfast promotes weight loss, improves diabetes, and decreases the need for insulin.
Roux-en Y gastric bypass increased the likelihood of nonvertebral fractures, including hip, wrist, and pelvic fractures.
New research suggests that there are separate pathways for the development of type 2 diabetes and obesity in patients with serious mental illness and demonstrate that there are important effects associated with sex and race or ethnicity.
Changes in weight influence the risk of diabetes, with lower risk of diabetes for obese individuals who lose weight vs stable obesity.
Results provide critical perspective on cardiovascular disease associated with overweight and obesity and challenge both the obesity paradox as well as the view that overweight is associated with greater longevity.
There was no significant difference in 12-month weight loss between the healthy low-fat and low-carbohydrate diets, and neither genotype pattern nor baseline insulin secretion was associated with the dietary effects on weight loss.
Microvascular decompression for trigeminal neuralgia, hemifacial spasm, and glossopharyngeal neuralgia was found to be a largely safe procedure, but patients with diabetes or obesity are an increased risk for reoperation within 30 days.
Plasma leptin levels are independently associated with sleep quality in obese patients with type 2 diabetes, but not in those who are not obese.
Children exposed to metformin had higher BMI and increased prevalence of overweight/obesity at 4 years of age.
Increases in waist circumference and waist-to-hip ratio are associated with a greater excess risk of myocardial infarction in women than men.
Women, not men, with T2D had an increased obesity-related standardized cancer incidence compared with women in the general population as early as 5 years before diabetes diagnosis.
Researchers conducted a retrospective case-control study of deliveries that happened from 2006 to 2016 to examine associations of laparoscopic sleeve gastrectomy with maternal and perinatal outcomes.
Researchers sought to characterize the pattern of weight loss and regain after patients complete a weight management program, and found that patients may begin to regain weight immediately after completion.
Researchers used data from the National Health and Nutrition Examination Survey for 1999 to 2016 to update the prevalence data on obesity trends among US children and adolescents age 2 to 19 years.
No significant difference in weight change between a healthy low-fat diet and a healthy low-carbohydrate diet. Genotype pattern or insulin secretion was not associated with dietary effects on weight loss.
Researchers observed detrimental effects of RYGB on bone turnover, mass, structure, and strength just 6 months postoperatively, and these effects persisted throughout the duration of the 12-month study.
The correlation between maternal pre-pregnancy overweight and childhood overweight at ages 1 and 3 years may be mediated by birth mode and infant gut microbiota.
Compared with control groups, behavior-based weight loss maintenance interventions are associated with less weight gain after cessation of the interventions.
For obese adults with type 2 diabetes, Roux-en-Y gastric bypass surgery is associated with greater weight loss, lower HbA1c, and reduced cardiovascular risk compared with intensive medical diabetes and weight management.
A recent survey examines the correlation between bariatric surgery and rates of continuation, discontinuation, or initiation of antidiabetes treatment 6 years after bariatric surgery compared with a matched control obese group.
Weight loss may result in improved pain, symptom severity, depression, and fibromyalgia scores in patients with obesity.
Higher concentrations of perfluoroalkyl substances are associated with greater weight regain in a diet-induced weight-loss setting.
The Gram-negative bacterium Helicobacter pylori was associated with increased marginal ulceration rates, but otherwise had little impact on bariatric surgery outcomes.
A recent study examined the extent to which rising BMI accounts for reductions in the rate of mortality using data from cohorts of the National Health and Nutrition Examination Survey and linked mortality files.
Eating speed can affect changes in obesity, body mass index, and waist circumference in patients with type 2 diabetes.
A man with morbid obesity, chronic obstructive pulmonary disease and obstructive sleep apnea presents with shortness of breath and dyspnea on exertion. What is the next step in care?
Public health policies should aim to reduce the consumption of sugar-sweetened beverages and encourage healthy alternatives such as water.
A recent study reported that the risk for suicide and non-fatal self-harm was increased after bariatric surgery.
High body fat levels are associated with elevated risk of estrogen receptor-positive breast cancer in postmenopausal women with normal body mass index.
The school-based healthy lifestyle program intervention encouraged healthy eating and physical activity and included a daily physical activity opportunities and termly cooking skills workshops.
Abdominal obesity and low inflammation levels independent of body mass index are inversely associated with fitness.
For preschool children, overweight/obesity is associated with more asthma symptom days and exacerbations among those not treated with a daily controller.
The amount of US health care resources devoted to treating obesity-related illness in US adults rose 29% from 2001 to 2015.
Sleep duration and circadian components of the sleep/wake cycle are linked to obesity-related eating behaviors and childhood body weight.
Pain management in patients who are obese can be a challenge due to their altered pharmacokinetic profile.
Patients were found to have improved pressure pain threshold at the patella and the wrist after weight loss associated with bariatric surgery, suggesting bariatric surgery may improve pain sensitization.
Findings indicate recent progress in reducing the prevalence of severe obesity among young children in the United States enrolled in the Special Supplemental Nutrition Program for Women, Infants, and Children.
Obesity and metabolic syndrome are associated with increased recurrence among men with prostate cancer who undergo radical prostatectomy.
Weight loss after bariatric surgery in adolescents predicts the degree of longitudinal improvement in elevated high-sensitivity C-reactive protein, hyperinsulinemia, dyslipidemia, and diabetes.
Body mass index and odds of overweight and/or obesity are increased with exposure to communities with higher rates of obesity.
Bariatric surgery is associated with lower risks of obesity-related comorbidities but a clinically important increased risk for complications compared with medical treatment.
Endocrinology Advisor Articles
- Diabetic Retinopathy Risk Not Increased With GLP-1 Receptor Agonist Use in T2D
- Concurrent Risk Factors and Microvascular Complications in Type 1 Diabetes
- Behavioral Weight Loss Interventions May Prevent Obesity
- Early Treatment Intensification and Faster Glycemic Control in T2D
- Executive Function Predicts T1D Management Into Emerging Adulthood
- Nutraceuticals May Benefit Patients Who Are Statin Intolerant
- Hypertension Treatments: ARBs
- Semaglutide vs Liraglutide for Weight Loss in Patients With Obesity
- Liraglutide May Lower Risk for Foot Amputation in Type 2 Diabetes
- Thyroid Hormone Levels, Body Composition, Insulin Resistance in Euthyroid Patients
- Physical Activity as a Lifestyle Factor Influencing Early Menopause
- Situation Framing, Language Can Influence Decision-Making
- Gains in Insurance Coverage Seen for Lesbian, Gay, Bisexual Adults
- Oral Contraceptives Associated With Ventricular Repolarization Alterations
- Incorporating Guidelines Into Clinical Practice: An Interview With Gary L. LeRoy, MD