Menopause

Characteristics of Menstrual Cycle Associated With Early Natural Menopause

Characteristics of Menstrual Cycle Associated With Early Natural Menopause

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Investigators examined the relationship between menstrual cycle characteristics in adolescence and early adulthood and the risk for early natural menopause.

'Good' Cholesterol May Not Be Good in Postmenopausal Women

'Good' Cholesterol May Not Be Good in Postmenopausal Women

High total HDL cholesterol in postmenopausal women may mask heart disease risk.

Ectopic Lipid Deposition and Insulin Resistance Higher in Postmenopausal Women

Ectopic Lipid Deposition and Insulin Resistance Higher in Postmenopausal Women

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The insulin sensitivity in post- and premenopausal women along with lipid deposition in the liver and skeletal muscle was examined.

Can Weight Gain After Smoking Cessation Be Reduced By Increasing Physical Activity in Postmenopausal Women?

Can Weight Gain After Smoking Cessation Be Reduced By Increasing Physical Activity in Postmenopausal Women?

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Investigators examined whether increase in physical activity may reduce weight gain after smoking cessation in postmenopausal women.

Effects of Menopause on Prolactinoma Treatment Outcomes Post-Dopamine Agonist Withdrawal

Effects of Menopause on Prolactinoma Treatment Outcomes Post-Dopamine Agonist Withdrawal

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Serum prolactin level 6 to 12 months after dopamine agonist withdrawal may be a useful predictor for clinical outcomes in patients with prolactinoma.

No Additional Benefits With Vaginal Estradiol Tablets, Moisturizers for Postmenopausal Vulvovaginal Symptoms

No Additional Benefits With Vaginal Estradiol Tablets, Moisturizers for Postmenopausal Vulvovaginal Symptoms

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Prescribed vaginal estradiol tablets and over-the-counter vaginal moisturizers may not be more effective than placebos for postmenopausal vulvovaginal symptoms.

Nutraceuticals Containing Equol May Be Effective for Postmenopausal Symptoms

Nutraceuticals Containing Equol May Be Effective for Postmenopausal Symptoms

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Equol-containing nutraceuticals may be beneficial for postmenopausal women with vaginal symptoms.

Many Women Report Vasomotor Symptoms in Their 60s

Many Women Report Vasomotor Symptoms in Their 60s

Symptoms more likely in those reporting fair health, history of non-spontaneous menopause

Menopausal Hormone Therapy Slows Cognitive Decline in Postmenopausal Women

Menopausal Hormone Therapy Slows Cognitive Decline in Postmenopausal Women

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Menopausal hormone therapy may slow cognitive decline in postmenopausal women with mild cognitive impairment.

Romosozumab Followed by Denosumab Effective for BMD Increase in Postmenopausal Women

Romosozumab Followed by Denosumab Effective for BMD Increase in Postmenopausal Women

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Romosozumab increased bone mineral density in postmenopausal women through increased bone formation and decreased bone resorption.

Sex Hormone Levels May Affect Postmenopausal Heart Disease Risk

Sex Hormone Levels May Affect Postmenopausal Heart Disease Risk

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Researchers assessed the effect of testosterone, estradiol, dehydroepiandrosterone, and sex hormone-binding globulin levels on coronary heart disease, heart failure, and cardiovascular disease in postmenopausal women.

Imvexxy Approved for Moderate to Severe Dyspareunia Due to Menopause

Imvexxy Approved for Moderate to Severe Dyspareunia Due to Menopause

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The FDA approval was supported by findings from a Phase 3, randomized, double-blind, placebo-controlled study that evaluated Imvexxy (4mcg and 10mcg) vs placebo from baseline to week 12.

Asthma Risk Increased for Premenopausal Women Using Oral Contraceptives

Asthma Risk Increased for Premenopausal Women Using Oral Contraceptives

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Oral contraceptive use in women of reproductive age may increase the risk for lifetime asthma.

Certain Foods May Impact Timing of Menopause

Certain Foods May Impact Timing of Menopause

Researchers studied women aged 40 to 65 years participating in the UK Women's Cohort Study, who had experienced natural menopause and responded to a food frequency questionnaire.

Anxiety Levels Tied to Bone Mineral Density in Postmenopausal Women

Anxiety Levels Tied to Bone Mineral Density in Postmenopausal Women

Anxiety levels are associated with bone mineral density and fracture risk in the lumbar spine and femoral neck among postmenopausal women.

Later Natural Menopause Can Benefit Future Verbal Memory

Later Natural Menopause Can Benefit Future Verbal Memory

Women who have a later natural menopause maintain a small benefit in verbal memory compared with women with earlier menopause.

Waist-to-Height Ratio Tied to Anxiety in Middle-Aged Women

Waist-to-Height Ratio Tied to Anxiety in Middle-Aged Women

Researchers conducted secondary analysis of data from a multicenter study of 5580 women from 11 Latin America countries in order to assess the association between waist-to-height ratio and anxiety.

Reproductive, Hormonal Factors Affect Risk for Total Knee Arthroplasty in Women

Reproductive, Hormonal Factors Affect Risk for Total Knee Arthroplasty in Women

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Researchers sought to identify associations of female reproductive factors with incidence of total knee arthroplasty in osteoarthritis.

Menopause Symptom Severity May Predict Heart Disease

Menopause Symptom Severity May Predict Heart Disease

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Researchers examined whether menopausal symptoms, quality of life, and depression are related to arterial stiffness, a risk factor for cardiovascular disease.

Effect of Menopausal Hormone Therapy on Cardiac Structure, Function

Effect of Menopausal Hormone Therapy on Cardiac Structure, Function

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Researchers examined the effect of menopausal hormone therapy on left ventricular and left atrial chamber structure and function changes, which are markers of subclinical cardiovascular disease.

Menopausal Hormone Therapy Linked to Reduced Abdominal Fat

Menopausal Hormone Therapy Linked to Reduced Abdominal Fat

Physicians should be aware that the benefit of menopausal hormone therapy (MHT) on body composition might rapidly disappear after its withdrawal and strongly encourage women to optimize nutrition and increase physical activity when stopping MHT.

Hormone Therapy May Impact Brain Structure, Cognition

Hormone Therapy May Impact Brain Structure, Cognition

Researchers assessed the effects of 2 frequently used formulations of menopausal hormone therapy on brain structure and cognition 3 years after the completion of a randomized clinical trial.

Bone Mineral Density Response Rates With Abaloparatide in Postmenopausal Women

Bone Mineral Density Response Rates With Abaloparatide in Postmenopausal Women

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At the 43-month endpoint, a total of 60.7% (307/506) of the abaloparatide followed by alendronate group had ≥3% increase in bone mass at all 3 sites (P<0.0001) vs. 24% (121/505) of the placebo followed by alendronate group.

Effect of High Androgen Levels on Cardiovascular Risk in Postmenopausal Women

Effect of High Androgen Levels on Cardiovascular Risk in Postmenopausal Women

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Researchers conducted a prospective, population-based cohort study to assess the risk for cardiovascular disease in postmenopausal women with increased androgen levels.

Oral Micronized Progesterone May Decrease Perimenopausal Vasomotor Symptoms

Oral Micronized Progesterone May Decrease Perimenopausal Vasomotor Symptoms

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Oral micronized progesterone may diminish hot flushes and night sweats in perimenopausal women, according to research presented at ENDO 2018.

Menopausal Hormone Therapy Linked to Kyphosis Severity

Menopausal Hormone Therapy Linked to Kyphosis Severity

Researchers examined the correlation between Cobb angle of kyphosis from lateral spine radiographs and pattern of self-reported menopausal hormone therapy use.

Damaging Effects of Gastric Bypass Surgery on Bone Mass and Microarchitecture

Damaging Effects of Gastric Bypass Surgery on Bone Mass and Microarchitecture

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Researchers observed detrimental effects of RYGB on bone turnover, mass, structure, and strength just 6 months postoperatively, and these effects persisted throughout the duration of the 12-month study.

Nonhormonal Options Available for Menopause Symptom Relief

Nonhormonal Options Available for Menopause Symptom Relief

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A nonhormonal treatment option for the relief of symptoms associated with menopause is now available alongside other drug-free supplements.

Hormone Therapy After Menopause Onset Reduces Stroke Risk

Hormone Therapy After Menopause Onset Reduces Stroke Risk

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The use of hormone therapy up to 5 years after onset of menopause is associated with a lower risk for ischemic and hemorrhagic stroke compared with late hormone therapy initiation or no hormone therapy use.

USPSTF's Final Recommendation on Menopausal HT for Chronic Disease Prevention

USPSTF's Final Recommendation on Menopausal HT for Chronic Disease Prevention

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To update its 2012 recommendation, the US Preventive Services Task Force reviewed evidence on the benefits and harms of systemic hormone therapy for the prevention of chronic conditions in postmenopausal women.

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