Lipids and Cholesterol

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Consensus Guidelines Reinforce Healthy Living for Lowering Cholesterol

Consensus Guidelines Reinforce Healthy Living for Lowering Cholesterol

A healthy lifestyle for lowering cholesterol should be emphasized for reducing cardiovascular risk across the life course.

Icosapent Ethyl Reduces Ischemic Event Risk in Patients With Hypertriglyceridemia Despite Statin Use

Icosapent Ethyl Reduces Ischemic Event Risk in Patients With Hypertriglyceridemia Despite Statin Use

The risk for the primary composite endpoint was significantly lowered by 25% among patients who received 2g of icosapent ethyl twice daily vs those who received placebo.

Long-Term Evolocumab Safe and Effective for Treating Hypercholesterolemia

Long-Term Evolocumab Safe and Effective for Treating Hypercholesterolemia

Evolocumab consistently reduced LDL-C with no increase in adverse events over a 5-year study period.

Statin-Induced Musculoskeletal AEs and Timing of Concurrent Treatment Examined

Statin-Induced Musculoskeletal AEs and Timing of Concurrent Treatment Examined

The data showed MAEs onset was significantly faster with atorvastatin and rosuvastatin compared with simvastatin; a comparison with other statins could not be established due to the small number of cases identified.

Nonadherence, Discontinuation High in First Year of Statin Therapy

Nonadherence, Discontinuation High in First Year of Statin Therapy

First-year nonadherence and discontinuation are high among older adults prescribed statins.

Lipidome Profiles Stratify Risk for Type 2 Diabetes

Lipidome Profiles Stratify Risk for Type 2 Diabetes

Early detection of lipidome characteristics could help identify the early onset of type 2 diabetes.

Statin-Induced Myalgia Unrelated to Muscle Coenzyme Q10 Level

Statin-Induced Myalgia Unrelated to Muscle Coenzyme Q10 Level

Statin therapy is associated with reduced mitochondrial complex II-linked respiration, and statin-induced myalgia is coupled to an increased intrinsic mitochondrial respiratory function, while intramuscular [coenzyme Q10] levels are unaltered.

Lack of Evidence for Noncardiovascular Outcomes With Statin Use

Lack of Evidence for Noncardiovascular Outcomes With Statin Use

There is a lack of convincing evidence for an association between statin use and noncardiovascular disease outcomes.

Hyperglycemia, Obesity, Hypertriglyceridemia Negatively Related to CAN in T2D

Hyperglycemia, Obesity, Hypertriglyceridemia Negatively Related to CAN in T2D

Hyperglycemia, obesity, and hypertriglyceridemia in type 2 diabetes are negatively related to indices of cardiovascular autonomic neuropathy.

Characteristics of Acquired Partial Lipodystrophy With Metabolic Abnormalities

Characteristics of Acquired Partial Lipodystrophy With Metabolic Abnormalities

Investigators analyze characteristics of participants with acquired partial lipodystrophy who developed severe metabolic abnormalities.

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