Infectious Diseases

Eplerenone May Improve Cardiovascular Disease Risk in HIV

Eplerenone May Improve Cardiovascular Disease Risk in HIV

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Researchers investigated effects of eplerenone on insulin sensitivity, inflammatory indices, and other metabolic parameters in HIV.

Metabolic Syndrome Associated With Higher ALT Levels in Chronic Hepatitis B

Metabolic Syndrome Associated With Higher ALT Levels in Chronic Hepatitis B

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Findings highlight the importance of screening for metabolic syndrome (MS) and the potential for MS to influence alanine aminotransferase and its interpretation in the context of HBV treatment decisions.

Insulin-Treated Diabetes Reduces Dysglycemia-Related Mortality in Sepsis

Insulin-Treated Diabetes Reduces Dysglycemia-Related Mortality in Sepsis

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In patients with insulin-treated diabetes and sepsis, increased highest glucose levels and glycemic variability have a significant illness severity-adjusted association with decreasing in-hospital mortality.

Increased Risk for Abdominal Obesity Found in People Living With HIV

Increased Risk for Abdominal Obesity Found in People Living With HIV

The Copenhagen Co-morbidity in HIV Infection (COCOMO) study assessed the association between risk factors for cardiovascular disease and HIV infection.

Rising Incidence of Diabetes in Adults With HIV on Antiretroviral Therapy

Rising Incidence of Diabetes in Adults With HIV on Antiretroviral Therapy

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More research is needed to better capture the interplay between prediabetes/diabetes and antiretroviral therapy in people with HIV.

Successful Hepatitis C Treatment May Reduce Risk for Developing T2D

Successful Hepatitis C Treatment May Reduce Risk for Developing T2D

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Among a large US cohort of patients treated for HCV, patients who achieved sustained virologic response demonstrated a substantially lower risk for development of type 2 diabetes than patients with treatment failure.

BMI Linked to Hepatocellular Carcinoma Risk in Chronic Hepatitis B Virus

BMI Linked to Hepatocellular Carcinoma Risk in Chronic Hepatitis B Virus

For patients with chronic hepatitis B virus, body mass index is significantly associated with increased risk of hepatocellular carcinoma, with the risk more pronounced for women than men.

Diabetes Risk May Be Reduced With Early Hepatitis C Virus Eradication

Diabetes Risk May Be Reduced With Early Hepatitis C Virus Eradication

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Early treatment and elimination of hepatitis C virus with direct-antiviral agents in patients with related cirrhosis may improve glucose tolerance and reduce the risk for diabetes development.

Weight Gain, Incident Glucose Disorders Associated With Long-Term HIV Therapy in Men

Weight Gain, Incident Glucose Disorders Associated With Long-Term HIV Therapy in Men

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Even modest gains in abdominal fat in HIV-positive men undergoing long-term viral treatment are associated with the development of diabetes.

Sulfonylureas May Increase Tuberculosis Risk in Type 2 Diabetes

Sulfonylureas May Increase Tuberculosis Risk in Type 2 Diabetes

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Patients with type 2 diabetes treated with sulfonylureas may be at a higher risk of contracting tuberculosis, compared with patients treated with metformin.

Type 1 Diabetes Associated With Higher Rates of Serious Infection

Type 1 Diabetes Associated With Higher Rates of Serious Infection

Patients with diabetes had higher rates for all 19 infection categories with the highest incidence rate ratios seen for bone and joint infections, sepsis, and cellulitis.

BMD Loss Slowed With Delayed Antiretroviral Therapy in HIV

BMD Loss Slowed With Delayed Antiretroviral Therapy in HIV

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Researchers examined the benefits and risks associated with delaying ART initiation to slow bone mineral density loss.

BMD of Femoral Neck Declines Twice as Fast in HIV-Infected Women

BMD of Femoral Neck Declines Twice as Fast in HIV-Infected Women

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Bone mineral density of the femoral neck, a significant predictor of fracture risk, declined nearly twice as quickly in HIV-infected women compared with HIV-infected men.

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