Hypoglycemia

Severe Hypoglycemia Associated With Increased Mortality Risk in T2D

Severe Hypoglycemia Associated With Increased Mortality Risk in T2D

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A study confirms whether severe hypoglycemia increases risk for all-cause mortality in patients with type 2 diabetes.

In-Hospital Tramadol Use Increases Hypoglycemia Risk in T1D, T2D

In-Hospital Tramadol Use Increases Hypoglycemia Risk in T1D, T2D

Results indicate that blood glucose monitoring should be conducted in hospitalized patients with diabetes.

Glucagon Response to Hypoglycemia Altered in Diabetes Secondary to Chronic Pancreatitis

Glucagon Response to Hypoglycemia Altered in Diabetes Secondary to Chronic Pancreatitis

Patients with type 2 diabetes and those with diabetes secondary to chronic pancreatitis have similarly impaired α-cell responses to oral glucose ingestion and hypoglycemia.

Management of Hypoglycemia: Insulin Degludec vs Insulin Glargine

Management of Hypoglycemia: Insulin Degludec vs Insulin Glargine

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Expert Q&A compares the effects of insulin degludec and insulin glargine U100 in patients with type 1 and type 2 diabetes.

Hypoglycemia Effectivey Managed With New Nasal Glucagon Device

Hypoglycemia Effectivey Managed With New Nasal Glucagon Device

Hypoglycemic episodes, moderate or severe, can effectively and efficiently be managed by nasal glucagon in adult patients with type 1 diabetes.

Reduced Awareness of Hypoglycemia in T1D With High-Intensity Interval Training

Reduced Awareness of Hypoglycemia in T1D With High-Intensity Interval Training

A single session of HIIT can "rapidly reduce" awareness of hypoglycemia in patients with type 1 diabetes.

Case Report: Insulin Autoimmune Syndrome Following Rituximab Therapy

Case Report: Insulin Autoimmune Syndrome Following Rituximab Therapy

A 37-year-old woman presented to the emergency department with recurrent dizziness following her recent pregnancy.

Hypoglycemia Treatment Recalled Due to Presence of Particulate Matter

Hypoglycemia Treatment Recalled Due to Presence of Particulate Matter

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A voluntary recall was announced for one specific lot of 25% dextrose injection, USP (infant).

Mortality In Type 2 Diabetes Increased With Severe Hypoglycemia Episode

Mortality In Type 2 Diabetes Increased With Severe Hypoglycemia Episode

Researchers identified hypoglycemia as an "under-recognized" risk factor for death and CVD in people with type 2 diabetes.

New Recommendation on Reporting Hypoglycemia in Clinical Trials

New Recommendation on Reporting Hypoglycemia in Clinical Trials

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Two diabetes associations are calling for more standard definitions of hypoglycemia to improve information on risk garnered during clinical trials.

Incidence of Hospitalization for Hypoglycemia Decreased in Type 1 Diabetes

Incidence of Hospitalization for Hypoglycemia Decreased in Type 1 Diabetes

For patients with type 1 diabetes, the incidence of hospitalization for hypoglycemia decreased over time in Denmark, with an 8.4% annual decrease.

Hypoglycemia in Hospitalized Patients Hikes Mortality Risk

Hypoglycemia in Hospitalized Patients Hikes Mortality Risk

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Hospitalized patients who experience hypoglycemia are at an increased risk for short-term and long-term mortality.

Gastric Emptying in Type 1 Diabetes Unaffected by Liraglutide

Gastric Emptying in Type 1 Diabetes Unaffected by Liraglutide

For individuals with type 1 diabetes, liraglutide therapy does not affect the rate of gastric emptying during hypoglycemia.

Educational Intervention Helps Reduce Severe Hypoglycemic Episodes

Educational Intervention Helps Reduce Severe Hypoglycemic Episodes

A brief, partly web-based educational intervention, HypoAware, is beneficial for reducing severe hypoglycemic episodes and improving hypoglycemia awareness compared with usual care.

Episodes of Dizziness, Weakness After Bariatric Surgery

Episodes of Dizziness, Weakness After Bariatric Surgery

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A patient came to the clinic to discuss her dizzy spells 4 years after her Roux-en-Y gastric bypass surgery.

Beta-Blocker Exposure Tied to Neonatal Hypoglycemia, Bradycardia

Beta-Blocker Exposure Tied to Neonatal Hypoglycemia, Bradycardia

Neonates born to mothers exposed to beta-blockers at the time of delivery have increased risk of neonatal hypoglycemia and bradycardia.

Hypoglycemia Risk Lowest With Gliclazide vs Newer Sulfonylureas

Hypoglycemia Risk Lowest With Gliclazide vs Newer Sulfonylureas

Of the newer generation sulfonylureas, gliclazide is associated with the lowest risk of hypoglycemia when added to metformin.

Glucagon May Be Ready for Prime Time

Glucagon May Be Ready for Prime Time

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Glucagon should be recognized as a lifesaver for hypoglycemia and a major treatment for diabetes.

Hypoglycemia Risk May Be Higher With Sulfonylureas in Late-Stage CKD

Hypoglycemia Risk May Be Higher With Sulfonylureas in Late-Stage CKD

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The risk of hypoglycemia is 5 times higher for diabetes patients with stage 4 or 5 chronic kidney disease (CKD) who currently use a sulfonylurea vs metformin.

Gastric Bypass Reduces Symptoms, Hormonal Responses to Hypoglycemia

Gastric Bypass Reduces Symptoms, Hormonal Responses to Hypoglycemia

Gastric bypass surgery is associated with reduced symptoms and neurohormonal responses to hypoglycemia, according to a study published in Diabetes.

Mixed Results Found for Use of Trained Dogs to Detect Hypoglycemia

Mixed Results Found for Use of Trained Dogs to Detect Hypoglycemia

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Patients were highly confident in their dogs' ability, but data demonstrated poor predictive value vs CGM.

Electronic Glycemic Management System May Reduce Inpatient Hypoglycemia

Electronic Glycemic Management System May Reduce Inpatient Hypoglycemia

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Patients using the electronic system had lower rates of hypoglycemia and less severe hypoglycemia.

Children With Type 1 Diabetes Frequently Experience Nocturnal Hypoglycemia

Children With Type 1 Diabetes Frequently Experience Nocturnal Hypoglycemia

Low bedtime glucose and daytime physical activity increase the risk for nocturnal hypoglycemia.

Sleep Deprivation Prolongs Cognitive Impairment Induced by Hypoglycemia

Sleep Deprivation Prolongs Cognitive Impairment Induced by Hypoglycemia

Sleep deprivation did not worsen cognitive impairment in type 1 diabetes, but prolonged post-hypoglycemia recovery.

Combination Insulin Degludec/Liraglutide Noninferior to Insulin Glargine in Type 2 Diabetes

Combination Insulin Degludec/Liraglutide Noninferior to Insulin Glargine in Type 2 Diabetes

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Type 2 diabetes patients treated with combination insulin therapy had improved glucose control that was on par with up-titration of basal insulin.

Hypoglycemia Decreases After Weight-Based Insuling Dosing in Hyperkalemia Patients

Hypoglycemia Decreases After Weight-Based Insuling Dosing in Hyperkalemia Patients

Weight-based insulin doses were associated with less hypoglycemia for patients weighing less than 95 kg.

Factors Linked to Failure to Achieve HbA1c Target in ACCORD Trial Identified

Factors Linked to Failure to Achieve HbA1c Target in ACCORD Trial Identified

Black race, severe hypoglycemia, and insulin use were linked to failure to reach HbA1c targets in the ACCORD trial.

Intranasal Glucagon Effective for Hypoglycemia in Type 1 Diabetes

Intranasal Glucagon Effective for Hypoglycemia in Type 1 Diabetes

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Intranasal glucagon was effective in treating insulin-induced hypoglycemia in type 1 diabetes.

Warfarin Plus Sulfonylureas May Raise Risk for Hospitalization

Warfarin Plus Sulfonylureas May Raise Risk for Hospitalization

Taking warfarin with a sulfonylurea like glipizide or glimepiride may increase risk for hospitalization.

Basal Insulin Peglispro Bested Glargine for Glycemic Control in Type 2 Diabetes

Basal Insulin Peglispro Bested Glargine for Glycemic Control in Type 2 Diabetes

In type 2 diabetes, peglispro was also tied to increased triglycerides, aminotransferases, and liver fat content.

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