Knee Osteoarthritis Not Improved With Vitamin D

Share this content:
Vitamin D supplementation do not alleviate pain of knee osteoarthritis.
Vitamin D supplementation do not alleviate pain of knee osteoarthritis.

(HealthDay News) — Vitamin D supplements do not appear to relieve pain or slow the progression of knee osteoarthritis in patients with low levels of the vitamin, according to a study published in the Journal of the American Medical Association.

Changhai Ding, MD, PhD, a professor at the University of Tasmania in Hobart, and colleagues randomly assigned 413 patients with knee osteoarthritis and low vitamin D levels to monthly treatment with either 50 000 IU of vitamin D a month or a placebo.

Over 2 years of follow-up, the investigators did not see any difference between the groups in reduced pain, change in tibiofemoral cartilage defects, or change in tibiofemoral bone marrow lesions.

"These data suggest a lack of evidence to support vitamin D supplementation for slowing disease progression or structural change in knee osteoarthritis," Dr Ding told HealthDay.

Reference

  1. Jin X, Jones G, Cicuttini F, et al. Effect of Vitamin D Supplementation on Tibial Cartilage Volume and Knee Pain Among Patients With Symptomatic Knee Osteoarthritis: A Randomized Clinical Trial. JAMA. 2016;315(10):1005-1013. doi:10.1001/jama.2016.1961.
You must be a registered member of Endocrinology Advisor to post a comment.

Sign Up for Free e-Newsletters

CME Focus