General Endocrinology

Normal Height Velocity Maintained With Reduced Growth Hormone Dose

Normal Height Velocity Maintained With Reduced Growth Hormone Dose

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Normal height velocity can be maintained in prepubertal children during the catch-up growth period by reducing growth hormone dosage by 50%.

Acromegaly Outlook Improves With Better Diagnostics and Treatment

Acromegaly Outlook Improves With Better Diagnostics and Treatment

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With greater awareness, better therapeutics, and more precise imaging and biochemical assays, patients with acromegaly can be diagnosed and treated earlier and are oftentimes cured.

Is BPA Safe? Endocrine Society Addresses FDA Position on Commercial BPA Use

Is BPA Safe? Endocrine Society Addresses FDA Position on Commercial BPA Use

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The Endocrine Society has expressed concern regarding the FDA's position on use of BPA in commercial products.

Early Manifestations, Sex Differences May Aid in Acromegaly Diagnosis

Early Manifestations, Sex Differences May Aid in Acromegaly Diagnosis

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Researchers described signs and symptoms in the years prior to acromegaly diagnosis and reported on differences between men and women in their clinical manifestations.

Adverse Events Associated With Diazoxide Treatment for Congenital Hyperinsulinism

Adverse Events Associated With Diazoxide Treatment for Congenital Hyperinsulinism

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Diazoxide treatment in children with congenital hyperinsulinism is associated most commonly with neutropenia, but also carries a risk for pulmonary hypertension.

Relacorilant Gets Orphan Drug Designation for Pancreatic Cancer

Relacorilant Gets Orphan Drug Designation for Pancreatic Cancer

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The Company is investigating the treatment as a combination with nab-paclitaxel (Abraxane; Celgene) for pancreatic cancers and other solid tumors.

Newer Hormonal Contraception May Reduce Ovarian Cancer Risk

Newer Hormonal Contraception May Reduce Ovarian Cancer Risk

There is a reduction in ovarian cancer risk associated with use of contemporary combined hormonal contraceptives.

Medicaid Expansion Programs Improve Women's Access to Reproductive Services

Medicaid Expansion Programs Improve Women's Access to Reproductive Services

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One-third of the women enrolled in Michigan's Medicaid expansion program reported improved access to birth control and family planning services.

Risk for Hypercalciuria With Recommended Dose of Vitamin D Supplement

Risk for Hypercalciuria With Recommended Dose of Vitamin D Supplement

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The upper level of vitamin D recommended by the Endocrine Society can result in frequent hypercalciuria.

Ivacaftor Improves Insulin Secretion in Children With Cystic Fibrosis

Ivacaftor Improves Insulin Secretion in Children With Cystic Fibrosis

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First-phase and glucose-potentiation of arginine-induced insulin secretion as assessed by acute C-peptide responses improved after the initiation of ivacaftor in children with cystic fibrosis.

Recent Increase in Contraception Use Noted Among US Teenagers

Recent Increase in Contraception Use Noted Among US Teenagers

Increases in use of one or more contraceptive methods, dual-method use, long-acting reversibles.

Medicaid Expansion Increases Access to Family Planning Services

Medicaid Expansion Increases Access to Family Planning Services

1 in 3 women of reproductive age report better ability to access birth control, family planning services.

Polycystic Ovary Syndrome May Be Associated With Autism in Offspring

Polycystic Ovary Syndrome May Be Associated With Autism in Offspring

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The prenatal sex steroid theory hypothesizes that women with PCOS would have heightened autistic traits and an increased rate of autism among their children.

High Prevalence of Sleep Apnea in Patients With Acromegaly

High Prevalence of Sleep Apnea in Patients With Acromegaly

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Sleep apnea is common in patients with acromegaly and is often diagnosed before the diagnosis of acromegaly.

Pancreatic Cancer and New-Onset Diabetes

Pancreatic Cancer and New-Onset Diabetes

New-onset adult diabetes mellitus appears to be both a risk factor for and a sequelae of pancreatic cancer.

Updated Consensus on Management of Acromegaly Includes New Recommendations

Updated Consensus on Management of Acromegaly Includes New Recommendations

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Experts in the management of acromegaly provide new recommendations on the medical management of acromegaly since the last published update in 2014.

Pasireotide Improves IGF-1 in Patients Resistant to Somatostatin Analogs

Pasireotide Improves IGF-1 in Patients Resistant to Somatostatin Analogs

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Monthly pasireotide injections may benefit patients with acromegaly who are resistant to first-generation somatostatin analogs.

Vitamin D Independently, Inversely Tied to Total, HDL, LDL Cholesterol in Children

Vitamin D Independently, Inversely Tied to Total, HDL, LDL Cholesterol in Children

Serum 25-hydroxyvitamin D [25(OH)D] is independently and inversely associated with total cholesterol, low-density lipoprotein (LDL) cholesterol, and high-density lipoprotein (HDL) cholesterol in children.

Are Women With Polycystic Ovary Syndrome More Likely to Develop Psychiatric Disorder?

Are Women With Polycystic Ovary Syndrome More Likely to Develop Psychiatric Disorder?

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Investigators observed an increased rate of obsessive compulsive disorder and somatization in women with polycystic ovary syndrome.

Cushing Syndrome Results in Poor Quality of Life Even After Remission

Cushing Syndrome Results in Poor Quality of Life Even After Remission

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Although patients reach clinical and biochemical remission, patients exposed to hypercortisolism do not show functional remission.

FDA Approves First Mobile App for Use in Preventing Pregnancy

FDA Approves First Mobile App for Use in Preventing Pregnancy

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The algorithm was designed to account for sperm survival, variation in cycle length, ovulation day, temperature fluctuations and the length of the follicular and luteal phases of the menstrual cycle.

Self-Administered Contraceptive Vaginal System Approved for Up to 1 Year of Use

Self-Administered Contraceptive Vaginal System Approved for Up to 1 Year of Use

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The safety and efficacy of Annovera was evaluated in 3 open-label clinical trials involving healthy women (ages 18 to 40).

Plasma Copeptin More Accurate for Diabetes Insipidus Diagnosis

Plasma Copeptin More Accurate for Diabetes Insipidus Diagnosis

In patients with hypotonic polyuria, the direct measurement of hypertonic saline-stimulated plasma copeptin has better diagnostic accuracy than the water-deprivation test.

Metyrapone Reduced Urinary-Free Cortisol Levels in Cushing Syndrome

Metyrapone Reduced Urinary-Free Cortisol Levels in Cushing Syndrome

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The treatment goals for Cushing syndrome are to normalize cortisol levels, reverse clinical symptoms, and if possible to remove the secreting neoplasm.

International PCOS Network Issues New Guidelines for Management and Diagnosis of PCOS

International PCOS Network Issues New Guidelines for Management and Diagnosis of PCOS

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International evidence-based guidelines include 166 recommendations and practice points to improve health outcomes of women with PCOS.

The Association Between Skin Diseases and Metabolic Syndrome

The Association Between Skin Diseases and Metabolic Syndrome

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Investigators examine the association between various skin conditions and metabolic syndrome.

Hepatitis B Infection May Increase the Risk for Pancreatic Cancer

Hepatitis B Infection May Increase the Risk for Pancreatic Cancer

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Investigators assessed the association of hepatitis B infection and pancreatic cancer, along with predictors of pancreatic cancer and mortality.

Men With Migraines May Have Increased Serum Estradiol, Androgen Deficiency

Men With Migraines May Have Increased Serum Estradiol, Androgen Deficiency

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Men with migraines were found to have increased levels of estradiol and to be more likely to have relative androgen deficiency compared with men without migraines.

Young Cancer Survivors Have High Risk of Endocrine Diseases

Young Cancer Survivors Have High Risk of Endocrine Diseases

Adolescent and young adult cancer survivors have a 73 percent higher risk of endocrine diseases.

Preconception Vitamin D Concentrations and Pregnancy Outcomes

Preconception Vitamin D Concentrations and Pregnancy Outcomes

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The association between preconception Vitamin D levels and pregnancy outcomes in women with previous pregnancy losses was examined.

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