General Endocrinology Archive

FDA Approves First Mobile App for Use in Preventing Pregnancy

FDA Approves First Mobile App for Use in Preventing Pregnancy

The algorithm was designed to account for sperm survival, variation in cycle length, ovulation day, temperature fluctuations and the length of the follicular and luteal phases of the menstrual cycle.

Cushing Syndrome Results in Poor Quality of Life Even After Remission

Cushing Syndrome Results in Poor Quality of Life Even After Remission

Although patients reach clinical and biochemical remission, patients exposed to hypercortisolism do not show functional remission.

Self-Administered Contraceptive Vaginal System Approved for Up to 1 Year of Use

Self-Administered Contraceptive Vaginal System Approved for Up to 1 Year of Use

The safety and efficacy of Annovera was evaluated in 3 open-label clinical trials involving healthy women (ages 18 to 40).

Plasma Copeptin More Accurate for Diabetes Insipidus Diagnosis

Plasma Copeptin More Accurate for Diabetes Insipidus Diagnosis

In patients with hypotonic polyuria, the direct measurement of hypertonic saline-stimulated plasma copeptin has better diagnostic accuracy than the water-deprivation test.

Metyrapone Reduced Urinary-Free Cortisol Levels in Cushing Syndrome

Metyrapone Reduced Urinary-Free Cortisol Levels in Cushing Syndrome

The treatment goals for Cushing syndrome are to normalize cortisol levels, reverse clinical symptoms, and if possible to remove the secreting neoplasm.

International PCOS Network Issues New Guidelines for Management and Diagnosis of PCOS

International PCOS Network Issues New Guidelines for Management and Diagnosis of PCOS

International evidence-based guidelines include 166 recommendations and practice points to improve health outcomes of women with PCOS.

The Association Between Skin Diseases and Metabolic Syndrome

The Association Between Skin Diseases and Metabolic Syndrome

Investigators examine the association between various skin conditions and metabolic syndrome.

Hepatitis B Infection May Increase the Risk for Pancreatic Cancer

Hepatitis B Infection May Increase the Risk for Pancreatic Cancer

Investigators assessed the association of hepatitis B infection and pancreatic cancer, along with predictors of pancreatic cancer and mortality.

Men With Migraines May Have Increased Serum Estradiol, Androgen Deficiency

Men With Migraines May Have Increased Serum Estradiol, Androgen Deficiency

Men with migraines were found to have increased levels of estradiol and to be more likely to have relative androgen deficiency compared with men without migraines.

Young Cancer Survivors Have High Risk of Endocrine Diseases

Young Cancer Survivors Have High Risk of Endocrine Diseases

Adolescent and young adult cancer survivors have a 73 percent higher risk of endocrine diseases.

Preconception Vitamin D Concentrations and Pregnancy Outcomes

Preconception Vitamin D Concentrations and Pregnancy Outcomes

The association between preconception Vitamin D levels and pregnancy outcomes in women with previous pregnancy losses was examined.

Prevalence and Predictors of Renal Calcification in Primary Hyperparathyroidism

Prevalence and Predictors of Renal Calcification in Primary Hyperparathyroidism

Investigators aimed to assess biochemical predictors of renal calcifications in patients with primary hyperparathyroidism.

Accuracy of Diagnostic Tests for GH Deficiency in Childhood Cancer Survivors

Accuracy of Diagnostic Tests for GH Deficiency in Childhood Cancer Survivors

The utility of IGF-I and IGFBP-3 for growth hormone testing in childhood cancer survivors was examined.

Increased Risk for Early Gonadarche Associated With Oxandrolone Treatment

Increased Risk for Early Gonadarche Associated With Oxandrolone Treatment

Investigators examine the onset of puberty and testicular function in prepubertal boys treated with oxandrolone.

Cross-Sex Hormone Therapy May Raise Vascular Event Risk in Transgender Persons

Cross-Sex Hormone Therapy May Raise Vascular Event Risk in Transgender Persons

The current study sought to compare the incidence of acute cardiovascular events among transgender persons.

Effects of Menopause on Prolactinoma Treatment Outcomes Post-Dopamine Agonist Withdrawal

Effects of Menopause on Prolactinoma Treatment Outcomes Post-Dopamine Agonist Withdrawal

Serum prolactin level 6 to 12 months after dopamine agonist withdrawal may be a useful predictor for clinical outcomes in patients with prolactinoma.

Conservative Monitoring Strategy for Non-Functioning Pituitary Adenomas Evaluated

Conservative Monitoring Strategy for Non-Functioning Pituitary Adenomas Evaluated

Investigators examined whether primary conservative monitoring is a safe strategy in patients with non-functioning pituitary adenomas.

Adjunctive Aripiprazole Lowers Prolactin Levels in Women With Psychosis

Adjunctive Aripiprazole Lowers Prolactin Levels in Women With Psychosis

These data suggest that aripiprazole can be safely used in premenopausal women to treat elevated prolactin levels and prolactin-related adverse effects.

Relationship Between Estradiol Level and Mortality in Elderly Men

Relationship Between Estradiol Level and Mortality in Elderly Men

Data from a prospective cohort study were used to determine the effect of estradiol levels on all-cause and cause-specific mortality in men aged ≥65 years.

Placebo Effect of Various Female Sexual Dysfunction Drug Txs Assessed

Placebo Effect of Various Female Sexual Dysfunction Drug Txs Assessed

For this study, the authors aimed to quantify this effect by conducting a systematic review of various databases to identify studies that included a placebo arm and used Female Sexual Function Index as a clinical outcome.

Revised Pooled Cohort Equations for CVD Risk Improve Accuracy of Estimates

Revised Pooled Cohort Equations for CVD Risk Improve Accuracy of Estimates

Investigators revised pooled cohort equations to improve clinical accuracy to predict risk for cardiovascular disease.

Many Drugs Made Available Via FDA Expanded Access Programs

Many Drugs Made Available Via FDA Expanded Access Programs

Half of meds ID'd in expanded access programs treat cancer; others for metabolic, endocrine diseases

Screening for Comorbid Conditions Not Adequate in Acromegaly

Screening for Comorbid Conditions Not Adequate in Acromegaly

Investigators examined the frequency of comorbidity screening and the frequency of comorbidities in patients with acromegaly.

Unplanned Pregnancies Prevalent Among HIV-Positive Women

Unplanned Pregnancies Prevalent Among HIV-Positive Women

Researchers examined unplanned pregnancies and contraceptive use among HIV-positive women in a cross-sectional study.

Timing of Serum Parathyroid Hormone Levels May Predict Postoperative Hypocalcemia

Timing of Serum Parathyroid Hormone Levels May Predict Postoperative Hypocalcemia

Serum intact parathyroid hormone levels may be an early marker to predict postthyroidectomy hypocalcemia.

Injectable Progestin-Only Contraceptives May Increase Risk for VTE

Injectable Progestin-Only Contraceptives May Increase Risk for VTE

Investigators examined the effect of progestin-only contraceptive on cardiometabolic outcomes, including stroke, MI, hypertension, diabetes, and VTE.

Hypoparathyroidism Treatment Granted Orphan Drug Designation

Hypoparathyroidism Treatment Granted Orphan Drug Designation

TransCon PTH is a long-acting prodrug of parathyroid hormone designed to restore PTH to physiologic levels, normalizing blood and urinary calcium levels, serum phosphate levels and bone turnover.

Worse Survival for BRCA Germline Mutation Carriers in Pancreatic CA

Worse Survival for BRCA Germline Mutation Carriers in Pancreatic CA

BRCA1/BRCA2 germline mutation carriers with pancreatic ductal adenocarcinoma have worse survival after resection.

Factors Associated With Decision Regret After Elective Oocyte Cryopreservation

Factors Associated With Decision Regret After Elective Oocyte Cryopreservation

Researchers identified factors associated with regret following elective oocyte cryopreservation among 201 women undergoing fertility preservation between 2012 and 2016.

LDL-C Reduction Examined With Different Evolocumab Dosing Regimens

LDL-C Reduction Examined With Different Evolocumab Dosing Regimens

For this study, researchers investigated the pharmacodynamics of evolocumab in two Phase 2 placebo-controlled studies (MENDEL and LAPLACE-TIMI 57) in order to determine which dosing regimens provided the most consistent LDL-C reduction.

Imvexxy Approved for Moderate to Severe Dyspareunia Due to Menopause

Imvexxy Approved for Moderate to Severe Dyspareunia Due to Menopause

The FDA approval was supported by findings from a Phase 3, randomized, double-blind, placebo-controlled study that evaluated Imvexxy (4mcg and 10mcg) vs placebo from baseline to week 12.

Long-Term Efficacy, Safety of Metreleptin for Generalized Lipodystrophy

Long-Term Efficacy, Safety of Metreleptin for Generalized Lipodystrophy

Investigators examined the safety and efficacy of metreleptin in patients with congenital or acquired generalized lipodystrophy.

Low Glycemic Index/Glycemic Load Decreases IGF-1 Levels in Adults With Acne

Low Glycemic Index/Glycemic Load Decreases IGF-1 Levels in Adults With Acne

Medical nutrition therapy may be a practical treatment option for patients with acne, based on the diet-induced endocrine effects on acne-promoting pathways described in this study.

Asthma Risk Increased for Premenopausal Women Using Oral Contraceptives

Asthma Risk Increased for Premenopausal Women Using Oral Contraceptives

Oral contraceptive use in women of reproductive age may increase the risk for lifetime asthma.

Certain Foods May Impact Timing of Menopause

Certain Foods May Impact Timing of Menopause

Researchers studied women aged 40 to 65 years participating in the UK Women's Cohort Study, who had experienced natural menopause and responded to a food frequency questionnaire.

Hormonal Antiandrogen Therapy for Acne May Help Reduce Antibiotic Use

Hormonal Antiandrogen Therapy for Acne May Help Reduce Antibiotic Use

Recognizing the increased need for antibiotic stewardship, the researchers consider HAAT to be a useful alternative to systemic antibiotic therapy that is effective and well tolerated among women with inflammatory acne.

One-Hour Plasma Glucose Useful Predictor of Diabetic Retinopathy

One-Hour Plasma Glucose Useful Predictor of Diabetic Retinopathy

One-hour plasma glucose is a useful predictor of retinopathy risk, has a predictive value similar to that of 2-hour plasma glucose, and may be considered as an alternative glucose time point during an oral glucose tolerance test.

Hormonal Contraceptives May Adversely Affect Psychological Health in Adolescent Girls

Hormonal Contraceptives May Adversely Affect Psychological Health in Adolescent Girls

This finding suggests an adverse effect of hormonal contraception on psychological health in adolescent girls.

Reproductive Goals Vary After Spontaneous Abortion

Reproductive Goals Vary After Spontaneous Abortion

Health care providers should offer family planning counseling to all women after spontaneous abortion, remaining responsive to individual patient needs.

DPP-4 Inhibitors Not Tied to Increased Risk for Acute Pancreatitis in Seniors

DPP-4 Inhibitors Not Tied to Increased Risk for Acute Pancreatitis in Seniors

Study provides evidence that DPP-4 inhibitors are not associated with an increased risk of acute pancreatitis in older adults overall. The positive association observed in patients with CVD could be due to chance or bias but merits further investigation.

FDA Puts New Restrictions on Permanent Birth Control Implant Essure

FDA Puts New Restrictions on Permanent Birth Control Implant Essure

The new Essure labeling restricts the sale and distribution of the device to only health care providers and facilities that provide information to patients about the risks and benefits of this device.

Eylea Meets Endpoint in Non-Proliferative Diabetic Retinopathy Trial

Eylea Meets Endpoint in Non-Proliferative Diabetic Retinopathy Trial

Results so far (at week 24) show more than half of patients who received Eylea experienced a 2-step or greater improvement from baseline on the DRSS vs. patients who received a sham injection (58% vs 6%; P<0.0001).

Red Meat Consumption Linked to Insulin Resistance and Steatohepatitis

Red Meat Consumption Linked to Insulin Resistance and Steatohepatitis

Researchers used a food frequency questionnaire and a detailed meat questionnaire to measure meat type and cooking method.

Lipid Metabolism Imbalance and Pathophysiology of Bipolar Disease

Lipid Metabolism Imbalance and Pathophysiology of Bipolar Disease

Abnormal ratios of omega-6 to omega-3 fatty acids were associated with the presence of bipolar disorder and the severity and duration of major depressive disorder.

Sudden Sensorineural Hearing Loss Recovery Lower With Metabolic Syndrome

Sudden Sensorineural Hearing Loss Recovery Lower With Metabolic Syndrome

Patients with metabolic syndrome have a lower rate of recovery from sudden sensorineural hearing loss than those without.

Weight Regain More Likely With Perfluoroalkyl Substances

Weight Regain More Likely With Perfluoroalkyl Substances

Higher concentrations of perfluoroalkyl substances are associated with greater weight regain in a diet-induced weight-loss setting.

Little Effect on Metabolic Risk Factors With Addition of SSRIs to Antipsychotics

Little Effect on Metabolic Risk Factors With Addition of SSRIs to Antipsychotics

A combination of selective serotonin reuptake inhibitors and antipsychotics does not lead to further deterioration of metabolic variables; however, metabolic monitoring should be performed.

Modern Contraceptive Use Increasing in Developing Nations

Modern Contraceptive Use Increasing in Developing Nations

Researchers used the Family Planning Estimation Tool to evaluate the performance of 68 of the 69 countries involved in the Family Planning 2020 initiative.

Spinal Cord Stimulation Reduces Pain in Diabetic Polyneuropathy

Spinal Cord Stimulation Reduces Pain in Diabetic Polyneuropathy

As many as one-quarter of individuals with diabetes will experience painful neuropathic symptoms for which treatment is limited.

FDA: Vitamin B7 May Interfere With Lab Tests for Hormone Levels

FDA: Vitamin B7 May Interfere With Lab Tests for Hormone Levels

One patient taking high levels of biotin has died following falsely low troponin test results when a troponin test known to have biotin interference was used.

Vitamin D Supplements May Reduce Depressive Symptoms, Cardiac Events

Vitamin D Supplements May Reduce Depressive Symptoms, Cardiac Events

Vitamin D supplement use is linked to reduced depressive symptoms and cardiac events for patients with moderate to severe depressive symptoms.

ACOG Guidelines Urge Screening for Female Athlete Triad

ACOG Guidelines Urge Screening for Female Athlete Triad

The female athlete triad includes low energy availability, menstrual dysfunction, and low bone density.

How Does Long-Term Schizophrenia Therapy Affect Metabolic Profiles?

How Does Long-Term Schizophrenia Therapy Affect Metabolic Profiles?

Modest changes were recorded in patients' weight, fasting glucose, and glycated hemoglobin levels with long-term schizophrenia therapy.

Can Vitamin D Deficiency Lead To Chronic Tension-Type Headaches?

Can Vitamin D Deficiency Lead To Chronic Tension-Type Headaches?

Serum 25(OH) D levels were associated with chronic tension-type headaches, musculoskeletal pain, and muscle weakness.

Timing of Cognitive Decline Linked to Insulin Resistance

Timing of Cognitive Decline Linked to Insulin Resistance

Researchers examined the link between insulin resistance, fasting insulin and glucose, glycated hemoglobin, and high-sensitivity C-reactive protein and decreased cognitive performance.

Rates of Vitamin D Deficiency In Children Increase

Rates of Vitamin D Deficiency In Children Increase

Researchers identified a 15-fold increase in diagnoses of vitamin D deficiency in children between 2008 and 2014.

Endocrine Society Responds to Presidential Immigration Order

Endocrine Society Responds to Presidential Immigration Order

The Endocrine Society has pledged to support legal efforts aimed at overturning the president's executive order.

Low Vitamin D May Raise Headache Risk in Men

Low Vitamin D May Raise Headache Risk in Men

Middle-aged men with low serum 25-hydroxyvitamin D (25(OH)D) concentrations had a markedly higher risk of frequent headache.

Low Vitamin D Associated With Incident Frailty in Older Women

Low Vitamin D Associated With Incident Frailty in Older Women

For older women, low vitamin D is associated with incident frailty.

Pokemon Go Led to Only Short-Term Increase in Physical Activity

Pokemon Go Led to Only Short-Term Increase in Physical Activity

Pokémon Go provided a slight, short-term boost to adults' physical activity levels, but it didn't last, according to a study published in the Christmas issue of The BMJ.

Neonatal Vitamin D Related to Multiple Sclerosis Risk

Neonatal Vitamin D Related to Multiple Sclerosis Risk

Low levels of neonatal vitamin D may be linked with risk of developing multiple sclerosis.

Further Examination of Link Between Vitamin D, Alzheimer's Disease Risk

Further Examination of Link Between Vitamin D, Alzheimer's Disease Risk

The present findings, in combination with those from prior observational research, provide a solid rationale for further randomized trials.

Acute Respiratory Infections Decreased With High-Dose Vitamin D

Acute Respiratory Infections Decreased With High-Dose Vitamin D

For long-term care facility residents, high-dose vitamin D3 supplementation is associated with reduced incidence of acute respiratory infection but increased incidence of falls.

Researchers Identify Association Between Low Maternal B12 and Higher Leptin

Researchers Identify Association Between Low Maternal B12 and Higher Leptin

Low maternal B12 is associated with higher leptin in cord blood, maternal adipose tissue, and placental tissue.

Community Pharmacists May Help Provide Preventive Care

Community Pharmacists May Help Provide Preventive Care

Community pharmacists are well suited to provide clinical preventive services, including education, screenings, and making referrals.

Vitamin D Supplementation May Have Varying Effects in Pregnancy

Vitamin D Supplementation May Have Varying Effects in Pregnancy

Several factors influence the impact of cholecalciferol supplementation in pregnant women.

Absenteeism Costs Related to Chronic Disease, Risk Factors

Absenteeism Costs Related to Chronic Disease, Risk Factors

Considerable costs are associated with absenteeism related to chronic diseases and health risk factors.

Use of Molecular Autopsy to Identify Cause of Unexpected Deaths

Use of Molecular Autopsy to Identify Cause of Unexpected Deaths

Molecular autopsy is able to uncover a likely or plausible cause of death in 40% of cases of unexpected death in young people.

Report Addresses Global Burden of Disease

Report Addresses Global Burden of Disease

The United States lags behind other advanced nations when it comes to infant mortality and the life expectancy of its citizens.

Changing Trends in Dietary Supplement Use Among Adults

Changing Trends in Dietary Supplement Use Among Adults

Data indicate a shift away from taking a multivitamin.

Endocrine-Disrupting Chemicals Associated With Reduced Vitamin D Levels

Endocrine-Disrupting Chemicals Associated With Reduced Vitamin D Levels

Phthalates and bisphenol A metabolites were inversely associated with circulating 25-hydroxyvitamin D levels in adults exposed to these chemicals.

Stress May Cancel Out Health Benefits of Eating Monounsaturated Fats

Stress May Cancel Out Health Benefits of Eating Monounsaturated Fats

However, stress does not seem to make the body's response to 'bad' fats even worse.

Glycemic Index Unreliable Indicator of Blood Glucose Response

Glycemic Index Unreliable Indicator of Blood Glucose Response

Glycemic index values of the same foods can vary widely and may be an unreliable indicator of blood glucose response.

More People Following Gluten-Free Diet

More People Following Gluten-Free Diet

The number of Americans following a gluten-free diet tripled between 2009 and 2014, but diagnoses of celiac disease remained stable during that same period.

Vitamin D May Be Beneficial in Asthma

Vitamin D May Be Beneficial in Asthma

For patients with asthma, vitamin D appears to reduce the risk of severe asthma exacerbations and health care use, according to a recently published review.

Smartphone Apps Help Patients Adopt Healthy Lifestyle

Smartphone Apps Help Patients Adopt Healthy Lifestyle

Various smartphone apps can help patients adopt a healthy lifestyle that might reduce risk of cardiovascular events.

Active Life Expectancy Varies According to Age, Race/Ethnicity

Active Life Expectancy Varies According to Age, Race/Ethnicity

Black people, especially black women, have lower percentage of remaining life spent active.

What Is the Link Between PTSD and Food Addiction?

What Is the Link Between PTSD and Food Addiction?

In veterans, expression suppression was significantly associated with eating disorder symptoms and mediated the connection between posttraumatic stress disorder (PTSD) and food addiction.

Biological Changes Evident in Non-Celiac Wheat Sensitivity

Biological Changes Evident in Non-Celiac Wheat Sensitivity

There are clear biological changes in patients presenting with non-celiac wheat sensitivity, according to research published in Gut.

Exercising 1 Hour Per Day May Combat Health Risks of Prolonged Sitting

Exercising 1 Hour Per Day May Combat Health Risks of Prolonged Sitting

Just 1 hour of physical activity a day may undo the increased mortality risk that comes with sitting 8 hours or more on a daily basis.

'Walking Meetings' May Improve Employee Activity Levels

'Walking Meetings' May Improve Employee Activity Levels

Walking meetings can increase on-the-job activity levels for white-collar workers.

Genetic Risk Score Correlates With BMI in Various Birth Cohorts

Genetic Risk Score Correlates With BMI in Various Birth Cohorts

The association between a multilocus genetic risk score for BMI and BMI is larger for individuals born in later birth cohorts.

Prediagnostic Vitamin D Levels Tied to Survival in Pancreatic Cancer

Prediagnostic Vitamin D Levels Tied to Survival in Pancreatic Cancer

Prediagnostic 25-hydroxyvitamin D (25[OH]D) levels are associated with survival in pancreatic cancer, according to a study published in the Journal of Clinical Oncology.

Diets That Include Healthy Fats May Not Cause Weight Gain

Diets That Include Healthy Fats May Not Cause Weight Gain

Diets with olive oil and nuts led to lower increase in waist circumference than patients on a low-fat diet.

Reducing Glycemic Index May Decrease Uric Acid Levels

Reducing Glycemic Index May Decrease Uric Acid Levels

A low glycemic index was associated with decreased uric acid levels, regardless of the percentage of carbohydrates in diet.

Nutrition Facts Label to Undergo Redesign by FDA

Nutrition Facts Label to Undergo Redesign by FDA

Added sugars and relevant portion sizes are among the highlights of revision.

Teens' Dietary Fat Intake May Affect Breast Density

Teens' Dietary Fat Intake May Affect Breast Density

Higher amounts of unhealthy fats during adolescence are tied to greater breast density later in life.

Vitamin D Receptor Levels Lower in Alopecia

Vitamin D Receptor Levels Lower in Alopecia

Significantly lower serum and tissue vitamin D receptor levels were seen in alopecia areata and androgenetic alopecia.

Fast Food Consumption May Increase Phthalate Exposure

Fast Food Consumption May Increase Phthalate Exposure

High consumption is linked to higher urinary levels of di(2-ethylhexyl) phthalate, diisononyl phthalate.

Processed Carbs, Sugary Drinks May Affect Cancer Risk

Processed Carbs, Sugary Drinks May Affect Cancer Risk

Preliminary study finds more reasons to improve diet.

Stimulant Banned From Competitive Sports Found in Diet Supplements

Stimulant Banned From Competitive Sports Found in Diet Supplements

FDA has warned makers of 8 products containing oxilofrine, also known as methylsynephrine.

Increasing Number of Seniors Mix Supplements With Medications

Increasing Number of Seniors Mix Supplements With Medications

Seniors taking supplements alongside medication are at risk for dangerous drug interactions.

Knee Osteoarthritis Not Improved With Vitamin D

Knee Osteoarthritis Not Improved With Vitamin D

Supplements do not slow disease progression or ease pain, even in patients with low levels of the vitamin D.

Ironman Triathletes May Be Susceptible to Hyponatremia

Ironman Triathletes May Be Susceptible to Hyponatremia

Triathletes may drink too much water during competition and end up with hyponatremia.

Chemical Exposure Decreased Among Teens After Change in Cosmetics

Chemical Exposure Decreased Among Teens After Change in Cosmetics

Hormone-disrupting chemicals decrease in teens after trying products without phthalates, parabens, triclosan, or oxybenzone.

Feasible Opportunities for Healthy Diet and Exercise Beneficial

Feasible Opportunities for Healthy Diet and Exercise Beneficial

Feasible opportunities for healthy diet and activity were linked to intentions, behaviors, and BMI.

Maternal Vitamin D Deficiency May Increase Multiple Sclerosis Risk in Children

Maternal Vitamin D Deficiency May Increase Multiple Sclerosis Risk in Children

Maternal vitamin D deficiency in early pregnancy linked to nearly 2-fold increased risk for multiple sclerosis.

Consistent Self-Weighing May Boost Eating Self-Efficacy

Consistent Self-Weighing May Boost Eating Self-Efficacy

High/consistent self-weighing is associated with increased eating self-efficacy over time.

Lower 25-Hydroxyvitamin D Levels Associated With Adverse Pathology in Radical Prostatectomy

Lower 25-Hydroxyvitamin D Levels Associated With Adverse Pathology in Radical Prostatectomy

For men with localized prostate cancer undergoing radical prostatectomy, serum 25-hydroxyvitamin D (25[OH]D) insufficiency/deficiency is associated with increased odds of adverse pathology.

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