General Endocrinology Archive
The algorithm was designed to account for sperm survival, variation in cycle length, ovulation day, temperature fluctuations and the length of the follicular and luteal phases of the menstrual cycle.
Although patients reach clinical and biochemical remission, patients exposed to hypercortisolism do not show functional remission.
The safety and efficacy of Annovera was evaluated in 3 open-label clinical trials involving healthy women (ages 18 to 40).
In patients with hypotonic polyuria, the direct measurement of hypertonic saline-stimulated plasma copeptin has better diagnostic accuracy than the water-deprivation test.
The treatment goals for Cushing syndrome are to normalize cortisol levels, reverse clinical symptoms, and if possible to remove the secreting neoplasm.
International evidence-based guidelines include 166 recommendations and practice points to improve health outcomes of women with PCOS.
Investigators examine the association between various skin conditions and metabolic syndrome.
Investigators assessed the association of hepatitis B infection and pancreatic cancer, along with predictors of pancreatic cancer and mortality.
Men with migraines were found to have increased levels of estradiol and to be more likely to have relative androgen deficiency compared with men without migraines.
Adolescent and young adult cancer survivors have a 73 percent higher risk of endocrine diseases.
The association between preconception Vitamin D levels and pregnancy outcomes in women with previous pregnancy losses was examined.
Investigators aimed to assess biochemical predictors of renal calcifications in patients with primary hyperparathyroidism.
The utility of IGF-I and IGFBP-3 for growth hormone testing in childhood cancer survivors was examined.
Investigators examine the onset of puberty and testicular function in prepubertal boys treated with oxandrolone.
The current study sought to compare the incidence of acute cardiovascular events among transgender persons.
Serum prolactin level 6 to 12 months after dopamine agonist withdrawal may be a useful predictor for clinical outcomes in patients with prolactinoma.
Investigators examined whether primary conservative monitoring is a safe strategy in patients with non-functioning pituitary adenomas.
These data suggest that aripiprazole can be safely used in premenopausal women to treat elevated prolactin levels and prolactin-related adverse effects.
Data from a prospective cohort study were used to determine the effect of estradiol levels on all-cause and cause-specific mortality in men aged ≥65 years.
For this study, the authors aimed to quantify this effect by conducting a systematic review of various databases to identify studies that included a placebo arm and used Female Sexual Function Index as a clinical outcome.
Investigators revised pooled cohort equations to improve clinical accuracy to predict risk for cardiovascular disease.
Half of meds ID'd in expanded access programs treat cancer; others for metabolic, endocrine diseases
Investigators examined the frequency of comorbidity screening and the frequency of comorbidities in patients with acromegaly.
Researchers examined unplanned pregnancies and contraceptive use among HIV-positive women in a cross-sectional study.
Serum intact parathyroid hormone levels may be an early marker to predict postthyroidectomy hypocalcemia.
Investigators examined the effect of progestin-only contraceptive on cardiometabolic outcomes, including stroke, MI, hypertension, diabetes, and VTE.
TransCon PTH is a long-acting prodrug of parathyroid hormone designed to restore PTH to physiologic levels, normalizing blood and urinary calcium levels, serum phosphate levels and bone turnover.
BRCA1/BRCA2 germline mutation carriers with pancreatic ductal adenocarcinoma have worse survival after resection.
Researchers identified factors associated with regret following elective oocyte cryopreservation among 201 women undergoing fertility preservation between 2012 and 2016.
For this study, researchers investigated the pharmacodynamics of evolocumab in two Phase 2 placebo-controlled studies (MENDEL and LAPLACE-TIMI 57) in order to determine which dosing regimens provided the most consistent LDL-C reduction.
The FDA approval was supported by findings from a Phase 3, randomized, double-blind, placebo-controlled study that evaluated Imvexxy (4mcg and 10mcg) vs placebo from baseline to week 12.
Investigators examined the safety and efficacy of metreleptin in patients with congenital or acquired generalized lipodystrophy.
Medical nutrition therapy may be a practical treatment option for patients with acne, based on the diet-induced endocrine effects on acne-promoting pathways described in this study.
Oral contraceptive use in women of reproductive age may increase the risk for lifetime asthma.
Researchers studied women aged 40 to 65 years participating in the UK Women's Cohort Study, who had experienced natural menopause and responded to a food frequency questionnaire.
Recognizing the increased need for antibiotic stewardship, the researchers consider HAAT to be a useful alternative to systemic antibiotic therapy that is effective and well tolerated among women with inflammatory acne.
One-hour plasma glucose is a useful predictor of retinopathy risk, has a predictive value similar to that of 2-hour plasma glucose, and may be considered as an alternative glucose time point during an oral glucose tolerance test.
This finding suggests an adverse effect of hormonal contraception on psychological health in adolescent girls.
Health care providers should offer family planning counseling to all women after spontaneous abortion, remaining responsive to individual patient needs.
Study provides evidence that DPP-4 inhibitors are not associated with an increased risk of acute pancreatitis in older adults overall. The positive association observed in patients with CVD could be due to chance or bias but merits further investigation.
The new Essure labeling restricts the sale and distribution of the device to only health care providers and facilities that provide information to patients about the risks and benefits of this device.
Results so far (at week 24) show more than half of patients who received Eylea experienced a 2-step or greater improvement from baseline on the DRSS vs. patients who received a sham injection (58% vs 6%; P<0.0001).
Researchers used a food frequency questionnaire and a detailed meat questionnaire to measure meat type and cooking method.
Abnormal ratios of omega-6 to omega-3 fatty acids were associated with the presence of bipolar disorder and the severity and duration of major depressive disorder.
Patients with metabolic syndrome have a lower rate of recovery from sudden sensorineural hearing loss than those without.
Higher concentrations of perfluoroalkyl substances are associated with greater weight regain in a diet-induced weight-loss setting.
A combination of selective serotonin reuptake inhibitors and antipsychotics does not lead to further deterioration of metabolic variables; however, metabolic monitoring should be performed.
Researchers used the Family Planning Estimation Tool to evaluate the performance of 68 of the 69 countries involved in the Family Planning 2020 initiative.
As many as one-quarter of individuals with diabetes will experience painful neuropathic symptoms for which treatment is limited.
One patient taking high levels of biotin has died following falsely low troponin test results when a troponin test known to have biotin interference was used.
Vitamin D supplement use is linked to reduced depressive symptoms and cardiac events for patients with moderate to severe depressive symptoms.
The female athlete triad includes low energy availability, menstrual dysfunction, and low bone density.
Modest changes were recorded in patients' weight, fasting glucose, and glycated hemoglobin levels with long-term schizophrenia therapy.
Serum 25(OH) D levels were associated with chronic tension-type headaches, musculoskeletal pain, and muscle weakness.
Researchers examined the link between insulin resistance, fasting insulin and glucose, glycated hemoglobin, and high-sensitivity C-reactive protein and decreased cognitive performance.
Researchers identified a 15-fold increase in diagnoses of vitamin D deficiency in children between 2008 and 2014.
The Endocrine Society has pledged to support legal efforts aimed at overturning the president's executive order.
Middle-aged men with low serum 25-hydroxyvitamin D (25(OH)D) concentrations had a markedly higher risk of frequent headache.
For older women, low vitamin D is associated with incident frailty.
Pokémon Go provided a slight, short-term boost to adults' physical activity levels, but it didn't last, according to a study published in the Christmas issue of The BMJ.
Low levels of neonatal vitamin D may be linked with risk of developing multiple sclerosis.
The present findings, in combination with those from prior observational research, provide a solid rationale for further randomized trials.
For long-term care facility residents, high-dose vitamin D3 supplementation is associated with reduced incidence of acute respiratory infection but increased incidence of falls.
Low maternal B12 is associated with higher leptin in cord blood, maternal adipose tissue, and placental tissue.
Community pharmacists are well suited to provide clinical preventive services, including education, screenings, and making referrals.
Several factors influence the impact of cholecalciferol supplementation in pregnant women.
Considerable costs are associated with absenteeism related to chronic diseases and health risk factors.
Molecular autopsy is able to uncover a likely or plausible cause of death in 40% of cases of unexpected death in young people.
The United States lags behind other advanced nations when it comes to infant mortality and the life expectancy of its citizens.
Data indicate a shift away from taking a multivitamin.
Phthalates and bisphenol A metabolites were inversely associated with circulating 25-hydroxyvitamin D levels in adults exposed to these chemicals.
However, stress does not seem to make the body's response to 'bad' fats even worse.
Glycemic index values of the same foods can vary widely and may be an unreliable indicator of blood glucose response.
The number of Americans following a gluten-free diet tripled between 2009 and 2014, but diagnoses of celiac disease remained stable during that same period.
For patients with asthma, vitamin D appears to reduce the risk of severe asthma exacerbations and health care use, according to a recently published review.
Various smartphone apps can help patients adopt a healthy lifestyle that might reduce risk of cardiovascular events.
Black people, especially black women, have lower percentage of remaining life spent active.
In veterans, expression suppression was significantly associated with eating disorder symptoms and mediated the connection between posttraumatic stress disorder (PTSD) and food addiction.
There are clear biological changes in patients presenting with non-celiac wheat sensitivity, according to research published in Gut.
Just 1 hour of physical activity a day may undo the increased mortality risk that comes with sitting 8 hours or more on a daily basis.
Walking meetings can increase on-the-job activity levels for white-collar workers.
The association between a multilocus genetic risk score for BMI and BMI is larger for individuals born in later birth cohorts.
Prediagnostic 25-hydroxyvitamin D (25[OH]D) levels are associated with survival in pancreatic cancer, according to a study published in the Journal of Clinical Oncology.
Diets with olive oil and nuts led to lower increase in waist circumference than patients on a low-fat diet.
A low glycemic index was associated with decreased uric acid levels, regardless of the percentage of carbohydrates in diet.
Added sugars and relevant portion sizes are among the highlights of revision.
Higher amounts of unhealthy fats during adolescence are tied to greater breast density later in life.
Significantly lower serum and tissue vitamin D receptor levels were seen in alopecia areata and androgenetic alopecia.
Findings were from 2 studies.
High consumption is linked to higher urinary levels of di(2-ethylhexyl) phthalate, diisononyl phthalate.
Preliminary study finds more reasons to improve diet.
FDA has warned makers of 8 products containing oxilofrine, also known as methylsynephrine.
Seniors taking supplements alongside medication are at risk for dangerous drug interactions.
Supplements do not slow disease progression or ease pain, even in patients with low levels of the vitamin D.
Triathletes may drink too much water during competition and end up with hyponatremia.
Hormone-disrupting chemicals decrease in teens after trying products without phthalates, parabens, triclosan, or oxybenzone.
Feasible opportunities for healthy diet and activity were linked to intentions, behaviors, and BMI.
Maternal vitamin D deficiency in early pregnancy linked to nearly 2-fold increased risk for multiple sclerosis.
High/consistent self-weighing is associated with increased eating self-efficacy over time.
For men with localized prostate cancer undergoing radical prostatectomy, serum 25-hydroxyvitamin D (25[OH]D) insufficiency/deficiency is associated with increased odds of adverse pathology.
Endocrinology Advisor Articles
- Behavioral Weight Loss Interventions May Prevent Obesity
- Executive Function Predicts T1D Management Into Emerging Adulthood
- Intensive Blood Pressure Therapy Lowers Cardiovascular Risk in Diabetes
- Association Between Urine Complement Proteins and Kidney Disease, Mortality in T2D
- Rates of Incident Type 2 Diabetes in Chronic Kidney Disease
- Hypertension Treatments: ARBs
- Semaglutide vs Liraglutide for Weight Loss in Patients With Obesity
- Liraglutide May Lower Risk for Foot Amputation in Type 2 Diabetes
- Thyroid Hormone Levels, Body Composition, Insulin Resistance in Euthyroid Patients
- Executive Function Predicts T1D Management Into Emerging Adulthood
- How Personalized Hospital Ratings May Drive Patient-Specific Care in the Digital Age
- LVAD in Heart Failure Linked to Improved Glycemic Control
- Fundamental Institutional Change Is Needed to Eliminate Sexual Harassment
- Gestational Diabetes Tied to Subsequent Glucose Disorders
- Association Health Plans Can Help Small Businesses Offer Coverage