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FOLLISTIM AQ VIAL
Infertility
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Drug Name:

FOLLISTIM AQ VIAL Rx

Generic Name and Formulations:
Follitropin beta (recombinant follicle-stimulating hormone) 75 IU, 150 IU; per vial; soln for SC or IM inj.

Company:
Merck & Co., Inc.

Therapeutic Use:

Indications for FOLLISTIM AQ VIAL:

Stimulation of multiple follicles in ovulatory patients undergoing Assisted Reproductive Technologies (ART). Induction of ovulation in patients with functional anovulatory infertility that is not due to ovarian failure.

Adult:

Individualize. ART: initially 150–225 IU daily in the early follicular phase (at least first 4 days), then adjust based on response; max 600 IU. Ovulation induction: initially 75 IU daily for up to 14 days; then adjust weekly by 37.5 IU based on response; max 300 IU. Both: induce final maturation of follicles or ovulation with 5000–10000 IU of hCG (see Precautions).

Children:

Not applicable.

Contraindications:

Ovarian failure. Uncontrolled thyroid or adrenal disease. Undiagnosed abnormal vaginal bleeding. Ovarian cysts or enlargement. Tumor of pituitary, breast, ovary, or uterus. Streptomycin or neomycin allergy. Pregnancy (Cat.X).

Warnings/Precautions:

Do complete gynecological and endocrinological exam first. Thromboembolic disorders. Do not give hCG if high estrogen levels or excessive numbers of ovarian follicles by ultrasound indicate a high risk of ovarian hyperstimulation syndrome (OHSS). Nursing mothers: not recommended.

See Also:

FOLLISTIM AQ CARTRIDGE

Adverse Reactions:

OHSS with pulmonary and vascular complications, ovarian enlargement or cysts, abdominal pain (discontinue if occurs), local reactions, risk of high order multiple births.

How Supplied:

Vials (0.5mL)—1
Cartridge (w. needles)—1
Follistim Pen (w. needles)—1

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