Diabetes

Dapagliflozin Lowers Heart Failure Hospitalization Rates in High-Risk Patients With Diabetes

Dapagliflozin Lowers Heart Failure Hospitalization Rates in High-Risk Patients With Diabetes

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Dapagliflozin was not associated with either a higher or lower rate of MACE compared with placebo in patients with type 2 diabetes who had or were at risk for atherosclerotic cardiovascular disease.

High Circulating Prolactin Concentrations May Lower Risk for Type 2 Diabetes

High Circulating Prolactin Concentrations May Lower Risk for Type 2 Diabetes

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High circulating total prolactin concentrations may be linked with a lower risk for type 2 diabetes in women.

ADA Issues Position Statement on Comprehensive Care for Pediatric T2D

ADA Issues Position Statement on Comprehensive Care for Pediatric T2D

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The American Diabetes Association issued a position statement outlining the recognition, management, and prevention of T2D in the pediatric population.

Peer Support Reduces Hospitalizations in People With Diabetes and Depression

Peer Support Reduces Hospitalizations in People With Diabetes and Depression

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Patients with diabetes and depressive symptoms who received community-based peer support for diabetes management reported less frequent acute care visits and hospitalizations than patients with diabetes without depressive symptoms.

Pathogenesis of Postprandial Hypoglycemia After Roux-en-Y Gastric Bypass in T2D

Pathogenesis of Postprandial Hypoglycemia After Roux-en-Y Gastric Bypass in T2D

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Postprandial hypoglycemia may occur after Roux-en-Y gastric bypass in patients with type 2 diabetes, independent from diabetes remission.

Multiple Daily Injections vs Insulin Pump Therapy in Pregnant Women With T1D

Multiple Daily Injections vs Insulin Pump Therapy in Pregnant Women With T1D

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Pregnant women with T1D who received MDI therapy had a larger decrease in HbA1c levels and were less likely to report gestational hypertension, neonatal hypoglycemia, and NICU admissions than women who used insulin pump therapy during pregnancy.

HbA1c Variability in General Population Increases Risk for Cardiovascular Events, All-Cause Mortality

HbA1c Variability in General Population Increases Risk for Cardiovascular Events, All-Cause Mortality

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People who do not have diabetes or cardiovascular disease but have high hemoglobin A1c variability tend to be at greater risk for major adverse cardiovascular events and all-cause mortality.

Prevalence of Arthritis in Adults With Prediabetes

Prevalence of Arthritis in Adults With Prediabetes

About 1 in 3 adults with prediabetes has arthritis, and half of those with both conditions are physically inactive and/or obese.

Measuring Time in Range During CGM May Be Useful Outcome Metric for Clinical Trials

Measuring Time in Range During CGM May Be Useful Outcome Metric for Clinical Trials

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TIR is strongly associated with the risk of microvascular complications and should be an acceptable end point for clinical trials.

Patients With T2D and Sickle-Cell Trait at Higher Risk for Complications

Patients With T2D and Sickle-Cell Trait at Higher Risk for Complications

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Diabetic complications were more prevalent in patients with both sickle-cell trait and T2D than in patients with T2D alone.

Long-Term Efficacy and Safety of Dapagliflozin for Type 1 Diabetes

Long-Term Efficacy and Safety of Dapagliflozin for Type 1 Diabetes

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After 52 weeks, dapagliflozin was well tolerated and led to a clinically relevant improvement in glycemic control and weight loss without additional risk for hypoglycemia.

Hypoglycemia Following Antifungal Treatment in Patient With Type 1 Diabetes

Hypoglycemia Following Antifungal Treatment in Patient With Type 1 Diabetes

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"This is the first report of decreased insulin requirements in a patient with [T1D] correlating with micafungin administration," noted the authors.

Plant-Based Diets Beneficial for Adults With Type 2 Diabetes

Plant-Based Diets Beneficial for Adults With Type 2 Diabetes

For adults with type 2 diabetes, plant-based diets can improve psychological health, quality of life, hemoglobin A1c levels, and weight.

Undiagnosed Prediabetes Prevalent in Men With Primary Infertility

Undiagnosed Prediabetes Prevalent in Men With Primary Infertility

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Approximately 15% of men experiencing infertility may have undiagnosed prediabetes.

Lipidome Profiles Stratify Risk for Type 2 Diabetes

Lipidome Profiles Stratify Risk for Type 2 Diabetes

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Early detection of lipidome characteristics could help identify the early onset of type 2 diabetes.

Prevalence of Gestational Diabetes Increased From 2012 to 2016

Prevalence of Gestational Diabetes Increased From 2012 to 2016

The prevalence of gestational diabetes was 6.0 percent in 2016, with a slight increase seen from 2012 to 2016.

Diabetes Education Week 2018: Patient Resources for Your Practice

Diabetes Education Week 2018: Patient Resources for Your Practice

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In recognition of National Diabetes Education Week, Endocrinology Advisor compiled a list of resources to assist clinicians when educating patients with diabetes about their condition.

Increasing Incidence of Diabetes After Immune Checkpoint Inhibitor Therapy

Increasing Incidence of Diabetes After Immune Checkpoint Inhibitor Therapy

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There is increased reporting of rapidly progressive diabetes associated with immune checkpoint inhibitor therapy.

Bardoxolone Methyl Leads to Weight Loss in T2D with Concurrent Chronic Kidney Disease

Bardoxolone Methyl Leads to Weight Loss in T2D with Concurrent Chronic Kidney Disease

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Treatment with bardoxolone methyl resulted in significant weight loss and showed no evidence of muscle wasting in patients with type 2 diabetes and stage IV chronic kidney disease.

Triponderal Mass Index Not Superior to BMI in Estimating Obesity Outcomes

Triponderal Mass Index Not Superior to BMI in Estimating Obesity Outcomes

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Triponderal mass index alone and in combination with body mass index (BMI) or subscapular skinfold thickness was not superior to BMI alone for estimating obesity-related outcomes in adulthood.

Hyperglycemia, Obesity, Hypertriglyceridemia Negatively Related to CAN in T2D

Hyperglycemia, Obesity, Hypertriglyceridemia Negatively Related to CAN in T2D

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Hyperglycemia, obesity, and hypertriglyceridemia in type 2 diabetes are negatively related to indices of cardiovascular autonomic neuropathy.

Canagliflozin Approved to Reduce Risk for Cardiovascular Events in T2D

Canagliflozin Approved to Reduce Risk for Cardiovascular Events in T2D

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The effect of Invokana on CV risk was evaluated in the CANVAS (CANagliflozin cardioVascular Assessment Study) Program in >10,000 adults with T2D who had established CV disease or were at risk for CV disease with ≥2 risk factors.

Weight Regain After Bariatric Surgery to Predict Clinical Outcomes

Weight Regain After Bariatric Surgery to Predict Clinical Outcomes

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Measures that quantified weight regain as a percentage of maximum weight lost had the strongest association and best fit with clinical outcomes.

Type 2 Diabetes an Independent Risk Factor for Coronary Artery Disease

Type 2 Diabetes an Independent Risk Factor for Coronary Artery Disease

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Type 2 diabetes is an independent risk factor for sudden cardiac arrest and death in patients with coronary artery disease with preserved ejection fraction.

Dual GIP, GLP-1 Receptor Agonist Effective for Weight Loss, Glucose Control in T2D

Dual GIP, GLP-1 Receptor Agonist Effective for Weight Loss, Glucose Control in T2D

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LY3298176, a dual GIP and GLP-1 receptor agonist, showed significantly better efficacy than dulaglutide with regard to glucose control and weight loss in type 2 diabetes.

Gastric Banding vs Metformin for Improved Insulin Sensitivity in Mild T2D

Gastric Banding vs Metformin for Improved Insulin Sensitivity in Mild T2D

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Gastric banding and metformin resulted in similar improvements in insulin sensitivity in moderately obese adults with impaired glucose tolerance or mild T2D over a 2-year period.

AHA, ADA, and Others Concerned Over Latest Trump Administration ACA Guidance

AHA, ADA, and Others Concerned Over Latest Trump Administration ACA Guidance

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More than 25 professional medical and patient advocacy organizations are in opposition to the Trump Administration's latest effort to undermine the Affordable Care Act.

Inadequate Reimbursement May Inhibit Diabetes Prevention Program

Inadequate Reimbursement May Inhibit Diabetes Prevention Program

The costs of delivering a new Medicare Diabetes Prevention Program (MDPP) may be higher than the expected reimbursement.

Ready-to-Use Glucagon Rescue Pen for Severe Hypoglycemia Under FDA Review

Ready-to-Use Glucagon Rescue Pen for Severe Hypoglycemia Under FDA Review

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The NDA included findings from multiple Phase 3 trials evaluating the safety, efficacy, and utility of the Xeris glucagon rescue pen auto-injector to treat severe hypoglycemia vs currently available glucagon emergency kits in children, adolescents, and adults with type 1 diabetes.

Dose-Dependent Relationship Between Smoking and Cardiovascular Complications in T1D

Dose-Dependent Relationship Between Smoking and Cardiovascular Complications in T1D

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There is a dose-dependent association between smoking and coronary heart disease in patients with type 1 diabetes.

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