Diabetes

Painful Diabetic Neuropathy: Challenges in Symptom Relief

Painful Diabetic Neuropathy: Challenges in Symptom Relief

A phase 2 clinical trial examined the efficacy of treating painful diabetic neuropathy (PDN) with filorexant, an orexin receptor antagonist.

Primary Plus Specialist Care in Diabetes with Compensated Cirrhosis: Is There A Benefit?

Primary Plus Specialist Care in Diabetes with Compensated Cirrhosis: Is There A Benefit?

Researchers examined care in patients with and without both primary care and gasteroenterologist/endocrinologist specialty care.

Efficacy of Online, Team-Based Game to Reduce HbA1C Explored

Efficacy of Online, Team-Based Game to Reduce HbA1C Explored

Sustained reduction in HbA1c has been linked to participation in an online diabetes self-management education game.

Do Intensive Lifestyle Changes Up Frailty Fracture Risk in Diabetes?

Do Intensive Lifestyle Changes Up Frailty Fracture Risk in Diabetes?

Frailty fracture risk, not overall fracture risk, was increased with intensive lifestyle intervention in diabetes.

Comparative Risk of Bladder Cancer With Pioglitazone vs DPP-4s, Sulfonylureas

Comparative Risk of Bladder Cancer With Pioglitazone vs DPP-4s, Sulfonylureas

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Pioglitazone in comparison to dipeptidyl-peptidase-4 inhibitors and sulfonylureas, is associated with an increased risk for bladder cancer.

High Risk of Insulin Resistance, PTSD Biomarkers in Military Veterans

High Risk of Insulin Resistance, PTSD Biomarkers in Military Veterans

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Eighty-three veterans with PTSD participated in a study examining biological pathways between PTSD and metabolic diseases.

Management of Hypoglycemia: Insulin Degludec vs Insulin Glargine

Management of Hypoglycemia: Insulin Degludec vs Insulin Glargine

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Expert Q&A compares the effects of insulin degludec and insulin glargine U100 in patients with type 1 and type 2 diabetes.

Lusduna Nexvue Follow-On Biologic Tentatively Approved by FDA

Lusduna Nexvue Follow-On Biologic Tentatively Approved by FDA

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Tentative FDA approval has been granted to Merck's follow-on biologic basal insulin injection.

Racial Differences in HbA1c Readings Examined

Racial Differences in HbA1c Readings Examined

Long-term differences in HbA1c readings were larger than expected in black vs white patients.

Increased Dysglycemia Screening With EHR-Supported Intervention

Increased Dysglycemia Screening With EHR-Supported Intervention

Intervention-based dysglycemia screening improved outcomes in study participants at 5 urban clinics.

Is Antiretroviral Therapy Linked to Diabetes Incidence in HIV?

Is Antiretroviral Therapy Linked to Diabetes Incidence in HIV?

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Patients with HIV had higher odds of developing diabetes when undergoing antiretroviral therapy, according to a meta-analysis of 41 observational studies.

Diabetic Ketoacidosis in Pregnancy May Lead to Fetal Death

Diabetic Ketoacidosis in Pregnancy May Lead to Fetal Death

Diabetic ketoacidosis led to fatal demise, preterm birth, and neonatal intensive care unit admissions.

Hypoglycemia Effectivey Managed With New Nasal Glucagon Device

Hypoglycemia Effectivey Managed With New Nasal Glucagon Device

Hypoglycemic episodes, moderate or severe, can effectively and efficiently be managed by nasal glucagon in adult patients with type 1 diabetes.

Increased Burden of Care With Diabetic Foot Ulcers, Infections

Increased Burden of Care With Diabetic Foot Ulcers, Infections

Diabetic foot ulcers correlated with a 3.4-fold increase in the odds of a patient needing an emergency department referral.

Obesity, Type 2 Diabetes Have Negative Effects on Brain Function

Obesity, Type 2 Diabetes Have Negative Effects on Brain Function

Obesity negatively affects brain function, particularly in patients with type 2 diabetes.

New Point-of-Care C Peptide Test Shows Promise

New Point-of-Care C Peptide Test Shows Promise

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A new point-of-care C peptide test may increase ease and access to testing for patients with type 1 and type 2 diabetes.

GLP-1 Analog Counteracts Antipsychotic-Induced Glucose Intolerance, Weight Gain

GLP-1 Analog Counteracts Antipsychotic-Induced Glucose Intolerance, Weight Gain

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Interventions seeking to counteract antipsychotic-induced weight gain and cardiometabolic disturbances have had limited success.

What Factors Increase Quality of Life in Teens With T1D?

What Factors Increase Quality of Life in Teens With T1D?

In all groups of participants, a lower HbA1c was associated with a better health-related quality of life in type 1 diabetes.

Algorithm Produces Personalized Glucose Forecast for Patients with T2D

Algorithm Produces Personalized Glucose Forecast for Patients with T2D

Machines were used to examine the glycemic impact of various meals to determine a glucose forecast.

American Diabetes Association 2017: Preview

American Diabetes Association 2017: Preview

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First look at research to be presented at ADA 2017.

Fast-Acting Insulin Aspart for Glycemic Control in Type 1 Diabetes

Fast-Acting Insulin Aspart for Glycemic Control in Type 1 Diabetes

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Both mealtime and postmeal faster insulin aspart are noninferior to mealtime conventional insulin aspart, regarding HbA1c change from baseline.

Efficacy of Anti-VEGF Treatments For Diabetic Retinopathy Explored

Efficacy of Anti-VEGF Treatments For Diabetic Retinopathy Explored

Three anti-vascular endothelial growth factor (anti-VEGF) therapies were linked to lowered rates of diabetic retinopathy.

CDC: Successful Start to National Diabetes Prevention Program

CDC: Successful Start to National Diabetes Prevention Program

Researchers at the CDC assessed participant-level data to determine the success of the National Diabetes Prevention Program.

FDA Adds Boxed Warning to Canagliflozin Due To Increased Leg and Foot Amputation Risk

FDA Adds Boxed Warning to Canagliflozin Due To Increased Leg and Foot Amputation Risk

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Results of 2 large clinical trials confirmed previous safety concerns surrounding canagliflozin therapy for type 2 diabetes.

pGDC59 Biomarker Identifies Pregnancy-Induced Glucose Intolerance

pGDC59 Biomarker Identifies Pregnancy-Induced Glucose Intolerance

One biomarker measurement during pregnancy can identify glucose intolerance with high sensitivity and specificity.

Diabetes Medication May Be Protective against Atrial Fibrillation

Diabetes Medication May Be Protective against Atrial Fibrillation

Use of thiazolidinediones reduced patient's risk of atrial fibrillation by 30%.

Lowering Systolic BP in Patients With T1D

Lowering Systolic BP in Patients With T1D

Febuxostat was found to have a modest impact in lowering systolic blood pressure among patients with type 1 diabetes.

Post-PCI HbA1c Levels Predict Cardiac, Cerebrovascular Events in Diabetes

Post-PCI HbA1c Levels Predict Cardiac, Cerebrovascular Events in Diabetes

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Intensive glycemic control has been found to reduce potential microvascular complications in patients with diabetes who undergo PCI.

Higher In-Hospital Mortality Rates in Type 1 vs Type 2 Diabetes With Acute MI

Higher In-Hospital Mortality Rates in Type 1 vs Type 2 Diabetes With Acute MI

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Patients with type 1 diabetes had higher mortality rates when admitted for acute myocardial infarction compared with patients with type 2 diabetes.

Are <i>RUNX1</i> Genes Linked to Proliferative Diabetic Retinopathy?

Are RUNX1 Genes Linked to Proliferative Diabetic Retinopathy?

Investigators found a link between the RUNX1 gene and proliferative diabetic retinopathy.

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