Dapagliflozin was not associated with either a higher or lower rate of MACE compared with placebo in patients with type 2 diabetes who had or were at risk for atherosclerotic cardiovascular disease.
High circulating total prolactin concentrations may be linked with a lower risk for type 2 diabetes in women.
The American Diabetes Association issued a position statement outlining the recognition, management, and prevention of T2D in the pediatric population.
Patients with diabetes and depressive symptoms who received community-based peer support for diabetes management reported less frequent acute care visits and hospitalizations than patients with diabetes without depressive symptoms.
Postprandial hypoglycemia may occur after Roux-en-Y gastric bypass in patients with type 2 diabetes, independent from diabetes remission.
Pregnant women with T1D who received MDI therapy had a larger decrease in HbA1c levels and were less likely to report gestational hypertension, neonatal hypoglycemia, and NICU admissions than women who used insulin pump therapy during pregnancy.
HbA1c Variability in General Population Increases Risk for Cardiovascular Events, All-Cause MortalityNovember 13, 2018
People who do not have diabetes or cardiovascular disease but have high hemoglobin A1c variability tend to be at greater risk for major adverse cardiovascular events and all-cause mortality.
About 1 in 3 adults with prediabetes has arthritis, and half of those with both conditions are physically inactive and/or obese.
TIR is strongly associated with the risk of microvascular complications and should be an acceptable end point for clinical trials.
Diabetic complications were more prevalent in patients with both sickle-cell trait and T2D than in patients with T2D alone.
After 52 weeks, dapagliflozin was well tolerated and led to a clinically relevant improvement in glycemic control and weight loss without additional risk for hypoglycemia.
"This is the first report of decreased insulin requirements in a patient with [T1D] correlating with micafungin administration," noted the authors.
For adults with type 2 diabetes, plant-based diets can improve psychological health, quality of life, hemoglobin A1c levels, and weight.
Approximately 15% of men experiencing infertility may have undiagnosed prediabetes.
Early detection of lipidome characteristics could help identify the early onset of type 2 diabetes.
The prevalence of gestational diabetes was 6.0 percent in 2016, with a slight increase seen from 2012 to 2016.
In recognition of National Diabetes Education Week, Endocrinology Advisor compiled a list of resources to assist clinicians when educating patients with diabetes about their condition.
There is increased reporting of rapidly progressive diabetes associated with immune checkpoint inhibitor therapy.
Treatment with bardoxolone methyl resulted in significant weight loss and showed no evidence of muscle wasting in patients with type 2 diabetes and stage IV chronic kidney disease.
Triponderal mass index alone and in combination with body mass index (BMI) or subscapular skinfold thickness was not superior to BMI alone for estimating obesity-related outcomes in adulthood.
Hyperglycemia, obesity, and hypertriglyceridemia in type 2 diabetes are negatively related to indices of cardiovascular autonomic neuropathy.
The effect of Invokana on CV risk was evaluated in the CANVAS (CANagliflozin cardioVascular Assessment Study) Program in >10,000 adults with T2D who had established CV disease or were at risk for CV disease with ≥2 risk factors.
Measures that quantified weight regain as a percentage of maximum weight lost had the strongest association and best fit with clinical outcomes.
Type 2 diabetes is an independent risk factor for sudden cardiac arrest and death in patients with coronary artery disease with preserved ejection fraction.
LY3298176, a dual GIP and GLP-1 receptor agonist, showed significantly better efficacy than dulaglutide with regard to glucose control and weight loss in type 2 diabetes.
Gastric banding and metformin resulted in similar improvements in insulin sensitivity in moderately obese adults with impaired glucose tolerance or mild T2D over a 2-year period.
More than 25 professional medical and patient advocacy organizations are in opposition to the Trump Administration's latest effort to undermine the Affordable Care Act.
The costs of delivering a new Medicare Diabetes Prevention Program (MDPP) may be higher than the expected reimbursement.
The NDA included findings from multiple Phase 3 trials evaluating the safety, efficacy, and utility of the Xeris glucagon rescue pen auto-injector to treat severe hypoglycemia vs currently available glucagon emergency kits in children, adolescents, and adults with type 1 diabetes.
There is a dose-dependent association between smoking and coronary heart disease in patients with type 1 diabetes.
Endocrinology Advisor Articles
- Long-Term Efficacy and Safety of Dapagliflozin for Type 1 Diabetes
- Measuring Time in Range During CGM May Be Useful Outcome Metric for Clinical Trials
- HbA1c Variability in General Population Increases Risk for Cardiovascular Events, All-Cause Mortality
- Safety and Effectiveness of the Most Common Bariatric Procedures Examined
- AHA, ADA Announce Joint Education Initiative to Reduce CVD Deaths in T2D
- High Circulating Prolactin Concentrations May Lower Risk for Type 2 Diabetes
- Online Tool Helps Patients With Advance Care Planning
- Dapagliflozin Lowers Heart Failure Hospitalization Rates in High-Risk Patients With Diabetes
- Direct-Acting Antiviral Therapy Reduced Risk for Incident T2D in Patients With Hepatitis C Infection
- Technological Breakthroughs in Medicine Move Physician-Patient Interactions From The Computer Screen Back to the Exam Room