Pediatric Diabetes, Diabetic Nephropathy Increased Over 11-Year Period

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Researchers noted an increase in prevalence of diabetes and diabetic nephropathy in children.
Researchers noted an increase in prevalence of diabetes and diabetic nephropathy in children.

Among pediatric patients who were commercially insured, the incidence of both diabetes and diabetic nephropathy increased over a period of 11 years, according to data published in Diabetes Care.

“Using the U.S. MarketScan commercial claims database, we found that the prevalence of diabetes (type 1 and type 2) among young people (ages 0-17 years) increased from 2002 to 2013, from 1.86 cases per 1000 children to 2.82 cases per 1000 children,” Lin Li, MD, PhD, research assistant professor of epidemiology in the Boston Collaborative Drug Surveillance Program at Boston University School of Public Health in Lexington, Massachusetts, told Endocrinology Advisor.

Dr Li and colleagues evaluated data from 96 171 pediatric patients with diabetes and 3161 pediatric patients with diabetic nephropathy during the study period, analyzing the incidence of each condition according to age, sex, and diabetes type.

Of those in the diabetic nephropathy group, 1509 patients were confirmed cases, while 2253 were deemed probable cases.

“Type 1 diabetes rose from 1.48 per 1000 to 2.32 per 1000 during this time, whereas type 2 rose from 0.38 per 1000 to 0.67 per 1000 from 2002-2006, then dropped from 0.56 per 1000 to 0.49 per 1000 thereafter,” Dr Li said. “During the same time period, the prevalence of pediatric patients with diabetic nephropathy rose as well, from 1.16% of all pediatric diabetes cases to 3.44%.”

When analyzed by sex, Dr Li and colleagues found that type 1 diabetes was more prevalent among boys, while type 2 diabetes and diabetic nephropathy was more prevalent among girls.

There was no significant association between diabetes type and incidence of diabetic nephropathy.

Regarding age, “Prevalence of diabetes and diabetic nephropathy was highest in children aged 12 to <18 years,” Dr Li said.

Reference

  1. Li L, Jick S, Breitenstein S, Michel A. Prevalence of Diabetes and Diabetic Nephropathy in a Large U.S. Commercially Insured Pediatric Population, 2002–2013. Diabetes Care. 2015;doi:10.2337/dc15-1710.
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