Racial Differences in HbA1c Readings Examined

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One hundred four black and white patients were recruited for the study.
One hundred four black and white patients were recruited for the study.

HealthDay News — Both biological and socioeconomic factors appear to play a role in higher HbA1c readings seen in black patients with diabetes, according to research published online in the Annals of Internal Medicine.

The study included 104 black patients and 104 white patients with type 1 diabetes. The participants were all aged 8 or older and had diabetes for at least 2 years. Patients were recruited from 10 diabetes centers in the United States. The study volunteers wore a continuous glucose monitor for up to 12 weeks. This device measured blood glucose every 15 minutes. After 12 weeks, HbA1c levels were tested.

The mean HbA1c was 9.1% for black patients and 8.3% for whites — a difference of 0.8%. However, based on their daily blood glucose tests, the difference between the 2 groups should have only been 0.4%, the study authors said.

Lead author, Richard Bergenstal, MD, executive director of the International Diabetes Center in Minneapolis, and colleagues found that both biological and socioeconomic factors appear to play a role in the difference. "It turned out to be a little bit of each. There's a biological difference, and we don't yet know why, but it accounts for about a half to a third of the blood glucose difference. The other part — which was an equal part or more — is from barriers to care," Bergenstal told HealthDay. What's important is that doctors and other health-care providers, as well as patients, don't just assume these differences are normal and inconsequential, he noted.

References

  1. Bergenstal RM, Gal RL, Connor CG, et al. Racial differences in the relationship of glucose concentrations and hemoglobin A1c levels. Ann Intern Med. 2017;167(2):95-102. doi:10.7326/M16-2596
  2. Selvin E, Sacks DB. Variability in the relationship of hemoglobin A1c and average glucose concentrations: how much does race matter? Ann Intern Med. 2017;167(2):131-132. doi:10.7326/M17-1231
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