Reduced Chemical Exposure May Decrease Diabetes Burden

Share this content:
Decreasing chemical exposure could prevent diabetes.
Decreasing chemical exposure could prevent diabetes.

HealthDay News -- For elderly adults, reduction of chemical exposures is associated with reduced burden and costs of diabetes, according to a study published in the Journal of Epidemiology & Community Health.

Leonardo Trasande, MD, MPP, from New York University in New York City, and colleagues used the Prospective Investigation of the Vasculature in Uppsala Seniors study (with about 1000 participants) to examine the independent contribution of dichlorodiphenyltrichloroethylene, polychlorinated biphenyls, and perfluoroalkyl substances to diabetes. Risk reductions were estimated assuming identical 25% reduction across levels of four compounds.

The researchers found that in cross-sectional analyses there was a 13% reduction in prevalent diabetes with reduction of chemical exposures, compared with a 40% decrease resulting from an identical 25% reduction in body mass index (BMI). Extrapolating to Europe, a total of 152,481 cases of diabetes and associated costs of €4.51 billion/year could be prevented, compared with 469,172 cases averted with BMI reduction.

"These findings support regulatory and individual efforts to reduce chemical exposures to reduce the burden and costs of diabetes," the researchers wrote.


  1. Trasande L, Lampa E, Lind L, Lind MP. Population attributable risks and costs of diabetogenic chemical exposures in the elderly. J Epidemiol Community Health. 2016 Oct 27. doi:10.1136/jech-2016-208006.
You must be a registered member of Endocrinology Advisor to post a comment.

Sign Up for Free e-Newsletters

CME Focus