Diabetes Archive

Availability and Affordability of Diabetes Medication Worldwide

Availability and Affordability of Diabetes Medication Worldwide

The affordability and availability of diabetes medications across multiple regions of the word were examined, along with the effects on the use of medications.

Intensive Blood Pressure Therapy Lowers Cardiovascular Risk in Diabetes

Intensive Blood Pressure Therapy Lowers Cardiovascular Risk in Diabetes

Intensive blood pressure therapy is associated with a significantly lower risk for serious cardiovascular events in the adults with diabetes.

Executive Function Predicts T1D Management Into Emerging Adulthood

Executive Function Predicts T1D Management Into Emerging Adulthood

Individuals with higher executive function performance at baseline experienced slower increases in HbA1c.

Higher Aldosterone Levels Tied to Incident Type 2 Diabetes Risk

Higher Aldosterone Levels Tied to Incident Type 2 Diabetes Risk

Higher levels of aldosterone are associated with insulin resistance and incident type 2 diabetes among multiethnic individuals.

FDA to Review Eylea for the Treatment of Non-Proliferative Diabetic Retinopathy

FDA to Review Eylea for the Treatment of Non-Proliferative Diabetic Retinopathy

The sBLA includes results from the Phase 3 PANORAMA trial, which enrolled 402 patients with NPDR.

Diabetic Retinopathy Risk Not Increased With GLP-1 Receptor Agonist Use in T2D

Diabetic Retinopathy Risk Not Increased With GLP-1 Receptor Agonist Use in T2D

Investigators examined whether the use of glucagon-like peptide-1 receptor agonists is associated with an increased risk for incident diabetic retinopathy.

AHA, ADA, and Others Express Concern Around Proposed Legislation to Protect Those With Preexisting Conditions

AHA, ADA, and Others Express Concern Around Proposed Legislation to Protect Those With Preexisting Conditions

The American Heart Association has published a statement in opposition of the latest Senate healthcare bill aimed at dismantling the Affordable Care Act.

Early Treatment Intensification and Faster Glycemic Control in T2D

Early Treatment Intensification and Faster Glycemic Control in T2D

Individuals with type 2 diabetes intensifying within 12 months of the index date had a significantly shorter median time from intensification to glycemic control.

Electronic Medical Record Reminders Improve HBV Vaccination in Diabetics

Electronic Medical Record Reminders Improve HBV Vaccination in Diabetics

Investigators assessed vaccination rates for hepatitis B vaccine series with electronic provider reminders in adults with diabetes.

Comparing Second-Generation Basal Insulin Analogs for Type 2 Diabetes

Comparing Second-Generation Basal Insulin Analogs for Type 2 Diabetes

Researchers concluded noninferiority between two basal insulin analogs after comparing safety and efficacy end points.

Concurrent Risk Factors and Microvascular Complications in Type 1 Diabetes

Concurrent Risk Factors and Microvascular Complications in Type 1 Diabetes

Investigators assessed the effect of complication burden and concurrent risk factors level on the risk of developing further microvascular complication.

Comparing Antidiabetic Drug Classes for Risk of Heart Failure

Comparing Antidiabetic Drug Classes for Risk of Heart Failure

The authors searched for randomized placebo-controlled trials (December 1, 2008 to November 24, 2017) involving 3 pharmacologic classes of antidiabetic medications to compare the effects of these agents on the risk of hospitalization for HF in T2DM patients.

Widespread Statin Use Not Recommended in Old, Very Old

Widespread Statin Use Not Recommended in Old, Very Old

Statin use is not associated with reduced risk of atherosclerotic cardiovascular disease or all-cause mortality among older adults without type 2 diabetes.

Diabetes Complications, Attempted Suicide Risk in Comorbid T1D and Schizophrenia

Diabetes Complications, Attempted Suicide Risk in Comorbid T1D and Schizophrenia

Although the association between type 2 diabetes and schizophrenia is well established, the link between type 1 diabetes and schizophrenia is less clear.

Trends in Cardiovascular Deaths for US Adults With and Without Diabetes

Trends in Cardiovascular Deaths for US Adults With and Without Diabetes

Investigators used data from the National Health Interview Survey and follow-up mortality data to estimate trends and disparities in CVD.

Comparing Efficacies of Second-Line Treatments in Type 2 Diabetes

Comparing Efficacies of Second-Line Treatments in Type 2 Diabetes

Researchers conducted a retrospective analysis to determine whether second-line treatment options sulfonylureas, DPP-4 inhibitors, and thiazolidinediones were associated with reduced HbA1c levels.

Polypharmacy Therapy for Schizophrenia Increases Risk for Type 2 Diabetes

Polypharmacy Therapy for Schizophrenia Increases Risk for Type 2 Diabetes

Investigators aimed to assess the effect of psychotropic medications, BMI, duration of schizophrenia, number of hospitalizations, and physical activity on the risk for T2D.

Low Fasting Insulin Associated With Long-Term Dementia Risk

Low Fasting Insulin Associated With Long-Term Dementia Risk

Having high insulin at baseline was associated with a greater risk for incident diabetes mellitus compared with low insulin values.

Excess Cardiac Risk Varies With Age of Onset of Type 1 Diabetes

Excess Cardiac Risk Varies With Age of Onset of Type 1 Diabetes

Excess cardiovascular risk varies with age at diagnosis of type 1 diabetes.

Adding Pharmacist to Team Can Improve Patient Outcomes

Adding Pharmacist to Team Can Improve Patient Outcomes

Pharmacist roles include helping with insulin treatment, virtual consults, and diabetes management.

Effects of Early Glycemic Control on Future Type 2 Diabetes Complications

Effects of Early Glycemic Control on Future Type 2 Diabetes Complications

To determine the legacy effect of early glycemic control, researchers followed a cohort of 34,737 patients with newly diagnosed diabetes for an average of 13 years.

Advanced Glycation End Products and esRAGE Predict Hip Fractures in Older Men

Advanced Glycation End Products and esRAGE Predict Hip Fractures in Older Men

Investigators assess whether circulating advanced glycation end products and esRAGE were associated with bone turnover and risk for fracture.

Vascular Risk Factors for Brain Calcification in Seniors Identified

Vascular Risk Factors for Brain Calcification in Seniors Identified

Diabetes and smoking are vascular risk factors associated with hippocampal calcification in older patients with memory issues.

Urological Complications Prevalent in Men and Women With Type 1 Diabetes

Urological Complications Prevalent in Men and Women With Type 1 Diabetes

The most prevalent complication was sexual dysfunction reported by both women and men, followed by urinary incontinence in women and low sexual desire in men.

WHO Issues Guidelines for Managing Diabetes in Low-Resource Settings

WHO Issues Guidelines for Managing Diabetes in Low-Resource Settings

WHO has developed guidelines for selecting therapy for treatment intensification in type 2 diabetes and on the use of insulin in type 1 and 2 diabetes in resource-poor settings.

Short-Duration Type 2 Diabetes Associated With Adverse Vascular Effects

Short-Duration Type 2 Diabetes Associated With Adverse Vascular Effects

Investigators examined carotid plaque composition and remodeling using magnetic resonance imaging in patients who were diagnosed with type 2 diabetes for a short duration.

Follow-Up Before Diagnosis Improved Metabolic Control in Children With Type I Diabetes

Follow-Up Before Diagnosis Improved Metabolic Control in Children With Type I Diabetes

Investigators sought to determine whether participants who were followed-up before their diagnosis of diabetes had improved metabolic control afterward.

Care Coordination Strategies Aid in Multiple Chronic Diseases

Care Coordination Strategies Aid in Multiple Chronic Diseases

Significant improvement for older adults with depression, COPD; diabetes, cardiovascular disease.

Elevated Depression Accelerates Disability in Older Adults With Newly Diagnosed Diabetes

Elevated Depression Accelerates Disability in Older Adults With Newly Diagnosed Diabetes

Older adults who experience elevated depressive symptoms after being newly diagnosed with diabetes show a faster trajectory of disability.

Increased First-Trimester HbA1c Predicts Gestational Diabetes

Increased First-Trimester HbA1c Predicts Gestational Diabetes

First-trimester HbA1c significantly improves GDM prediction compared with conventional risk factors.

Medicaid Expansion Linked to Increase in Diabetes Prescription Fills

Medicaid Expansion Linked to Increase in Diabetes Prescription Fills

Researchers from the University of Southern California in Los Angeles examined the impacts of Medicaid expansion on access to diabetes medications.

FDA: Cases of Rare Gangrene of Genital Area Tied to Diabetes Drug Class

FDA: Cases of Rare Gangrene of Genital Area Tied to Diabetes Drug Class

The infection developed within several months of the patients starting SGLT2 therapy and the drug was discontinued in most cases. All patients required surgery and there was 1 reported death.

Evaluating Excess Risk for Heart Failure Hospitalization in Type 2 Diabetes

Evaluating Excess Risk for Heart Failure Hospitalization in Type 2 Diabetes

Investigators examined the excess risk for heart failure in patients with type 2 diabetes and compared the risk with that in the general population without diabetes.

The Relationship Between Hip/Knee Osteoarthritis and Risk for Incident Diabetes

The Relationship Between Hip/Knee Osteoarthritis and Risk for Incident Diabetes

Bilateral hip or knee osteoarthritis was significantly associated with a 16% to 25% increased risk for incident diabetes.

Assessing the Evidence of Aspirin for Primary Prevention in Diabetes

Assessing the Evidence of Aspirin for Primary Prevention in Diabetes

The substantial burden of cardiovascular disease in patients with diabetes has led to the exploration of various cardiovascular disease prevention strategies, including the use of aspirin.

High Prevalence of Diabetes in Patients With Severe Mental Illness

High Prevalence of Diabetes in Patients With Severe Mental Illness

Antipsychotic-treated patients with severe mental illnesses have a high prevalence of diabetes and prediabetes.

PedsQL 3.2 Diabetes Modules Display Excellent Measurement Ability

PedsQL 3.2 Diabetes Modules Display Excellent Measurement Ability

The PedsQL 3.2 can assist in identify new and existing therapeutic interventions for individuals with different diabetes-specific health-related quality of life profiles.

Examining Excess Risk Factors for Mortality, Cardiovascular Events in T2D

Examining Excess Risk Factors for Mortality, Cardiovascular Events in T2D

Investigators sought to determine whether excess risk factors for death and cardiovascular events in patients with type 2 diabetes could be reduced or eliminated.

Antipsychotics Adversely Affect Adiposity and Insulin Sensitivity in Youths

Antipsychotics Adversely Affect Adiposity and Insulin Sensitivity in Youths

While antipsychotic treatments can improve behavioral symptoms, risk of hyperglycemia and weight gain should inform careful consideration of antipsychotic use in young patients.

Gender Differences Found When Rapid Weight Loss Occurs on Low-Energy Diet

Gender Differences Found When Rapid Weight Loss Occurs on Low-Energy Diet

A low-energy diet for weight loss had different effects between men and women after weight reduction.

Dual Diagnosis of Diabetes and Eating Disorders

Dual Diagnosis of Diabetes and Eating Disorders

Among the many conditions that may co-occur with diabetes, eating disorders are common.

Age at Onset of Type 1 Diabetes Effects Mortality and Cardiovascular Complications

Age at Onset of Type 1 Diabetes Effects Mortality and Cardiovascular Complications

Investigators examine whether age of onset of type 1 diabetes affects mortality and cardiovascular risk.

Effect of Posttraumatic Stress Disorder and Obesity on Type 2 Diabetes

Effect of Posttraumatic Stress Disorder and Obesity on Type 2 Diabetes

In the absence of obesity, patients with PTSD are not at an increased risk for type 2 diabetes.

Changes in Glucose Regulation in Parkinson Disease

Changes in Glucose Regulation in Parkinson Disease

Investigators sought to determine whether patients with moderate to advanced Parkinson disease have impaired glucose levels during an Oral Glucose Tolerance Test.

Two Strategies for Preventing Diabetes in Minority Patients

Two Strategies for Preventing Diabetes in Minority Patients

Recognizing the barriers to care for minority patients with type 2 diabetes could reduce the incidence of type 2 diabetes nationwide.

Link Between Gestational Diabetes and Risk for CVD and Diabetes in Hispanic/Latina Population

Link Between Gestational Diabetes and Risk for CVD and Diabetes in Hispanic/Latina Population

Investigators sought to compare cardiovascular risk and disease prevalence in the Hispanic and Latina population in the United States with and without a history of gestational diabetes.

Clinical Characteristics Altering Risks and Benefits of Sulfonylureas and Thiazolidinedione Therapy in T2D

Clinical Characteristics Altering Risks and Benefits of Sulfonylureas and Thiazolidinedione Therapy in T2D

Investigators examined patterns of benefits and risks associated between the sex and BMI of different patient subgroups and sulfonylurea and thiazolidinedione therapies.

Weight Gain After Quitting Smoking May Increase Risk for T2D

Weight Gain After Quitting Smoking May Increase Risk for T2D

But temporary increase in type 2 diabetes risk does not attenuate benefits on total, CVD mortality.

Bi-Directional Association Observed Between Obstructive Sleep Apnea and Diabetes

Bi-Directional Association Observed Between Obstructive Sleep Apnea and Diabetes

Clinical awareness of the bi-directional association may improve prevention and treatment of both diseases.

Bariatric Surgery Reduces Incidence of Microvascular Disease in Type 2 Diabetes

Bariatric Surgery Reduces Incidence of Microvascular Disease in Type 2 Diabetes

Investigators examined the effect of bariatric surgery and the incidence of microvascular complications in type 2 diabetes.

Risk of autism in offspring linked to maternal pregestational diabetes and severe obesity

Maternal prepregnancy obesity without pregestational diabetes mellitus (PGDM) or gestational diabetes mellitus (GDM) was associated with a slightly increased risk of having a child with a neurodevelopmental or psychiatric disorder.

FDA to Review Gimoti for Diabetic Gastroparesis in Adult Women

FDA to Review Gimoti for Diabetic Gastroparesis in Adult Women

The FDA has set a Prescription Drug User Fee Act target date of April 1, 2019.

Treating Painful Diabetic Peripheral Neuropathy With Electroacupuncture

Treating Painful Diabetic Peripheral Neuropathy With Electroacupuncture

Investigators sought to determine the safety and efficacy of electroacupuncture for painful diabetic peripheral neuropathy.

Predictors of Weight Loss in Postpartum Women With Gestational Diabetes

Predictors of Weight Loss in Postpartum Women With Gestational Diabetes

Modifiable pregnancy and postpartum factors associated with at least 75% of weight loss in postpartum women with gestational diabetes have been examined.

DPP-4 Inhibitors and Incidence of Rheumatoid Arthritis in Type 2 Diabetes

DPP-4 Inhibitors and Incidence of Rheumatoid Arthritis in Type 2 Diabetes

Investigators sought to determine whether the use of dipeptidyl peptidase-4 inhibitors is associated with the incidence of rheumatoid arthritis.

Healthy Lifestyle With Diabetes Cuts Cardiovascular Risk

Healthy Lifestyle With Diabetes Cuts Cardiovascular Risk

Greater adherence to an overall healthy lifestyle is associated with a substantially lower risk for cardiovascular disease.

Diabetes Screening Rates Suboptimal Among Patients With Rheumatoid Arthritis

Diabetes Screening Rates Suboptimal Among Patients With Rheumatoid Arthritis

Compliance with general population guidelines for diabetes screening was suboptimal among patients with rheumatoid arthritis.

Diabetes Treatments

Antidiabetic agents for the treatment of diabetes including maintenance and max doses.

Bone Mineral Density Loss Eventually Stabilizes in Men With Type 1 Diabetes

Bone Mineral Density Loss Eventually Stabilizes in Men With Type 1 Diabetes

Investigators determined that reductions in bone mineral density in men with type 1 diabetes occur early in the course of the disease.

Adjunct Dapagliflozin Improves Glycemic Control But Increases Ketoacidosis in T1D

Adjunct Dapagliflozin Improves Glycemic Control But Increases Ketoacidosis in T1D

Investigators examined safety and efficacy of adjunct therapy to insulin for patients with type 1 diabetes who are not adequately controlled.

ADA Releases Updated Guidelines for Managing Pediatric Type 1 Diabetes

ADA Releases Updated Guidelines for Managing Pediatric Type 1 Diabetes

It is critical for us to remember that children are not little adults. Pediatric-onset diabetes is different from adult-onset diabetes due to its distinct epidemiology, pathophysiology, developmental considerations, and response to therapy.

High Albumin-to-Creatinine Ratio Associated With Increased Risk for Microalbuminuria and Future CVD in Adolescents

High Albumin-to-Creatinine Ratio Associated With Increased Risk for Microalbuminuria and Future CVD in Adolescents

The association between albumin-to-creatinine ratio and risk for diabetic nephropathy and CVD was examined over 2 to 4 years.

Sitagliptin May Improve Glycemic Control Better Than Dapagliflozin in T2D With Mild Renal Insufficiency

Sitagliptin May Improve Glycemic Control Better Than Dapagliflozin in T2D With Mild Renal Insufficiency

The safety and efficacy of sitagliptin vs dapagliflozin in patients with type 2 diabetes and renal insufficiency was examined.

Intermittent vs Continuous Energy-Restricted Diet: Effects on Glycemic Control and Weight Loss T2D

Intermittent vs Continuous Energy-Restricted Diet: Effects on Glycemic Control and Weight Loss T2D

Intermittent energy restriction diet may be an effective alternative diet strategy for reducing HbA1c in patients with type 2 diabetes.

Smoothing the Care Team Transition for Youth With Type 1 Diabetes

Smoothing the Care Team Transition for Youth With Type 1 Diabetes

The transition from pediatric to adult care for type 1 diabetes should be a gradual process, with a plan to make the change when the patient is ready, not at a pre-determined time.

Second-Line Therapies Show Benefit Over Metformin Monotherapy in T2D

Second-Line Therapies Show Benefit Over Metformin Monotherapy in T2D

Investigators assessed the effect of second-line therapies on weight, HbA1c, and treatment persistence over 18 months in patients who had received metformin monotherapy.

Single Diagnostic Threshold May Not Be Feasible for Gestational Diabetes

Single Diagnostic Threshold May Not Be Feasible for Gestational Diabetes

Uniform application of gestational diabetes diagnostic thresholds may not be appropriate in populations across the world.

Dapagliflozin Plus Omega-3 Carboxylic Acids for Non-Alcoholic Fatty Liver Disease in T2D

Dapagliflozin Plus Omega-3 Carboxylic Acids for Non-Alcoholic Fatty Liver Disease in T2D

Combination treatment with dapagliflozin plus omega-3 carboxylic acids may reduce fat content in nonalcoholic fatty liver disease.

One in Four Older Adults With Diabetes Uses Alternative Meds

One in Four Older Adults With Diabetes Uses Alternative Meds

More than 25 percent of older U.S. adults with diabetes use some type of complementary and alternative medicine.

HbA1c-Corrected FRAX Score May Better Predict Fracture Risk in Type 2 Diabetes

HbA1c-Corrected FRAX Score May Better Predict Fracture Risk in Type 2 Diabetes

A corrected HbA1C factor may improve the ability to predict the risk for fracture by the FRAX algorithm in T2D.

Reducing Diabetes Distress in Adults With T1D: A Comparison of 2 Interventions

Reducing Diabetes Distress in Adults With T1D: A Comparison of 2 Interventions

Investigators compared 2 interventions to reduce diabetes distress and improve glycemic control in patients with T1D.

Estimating Risk Factors and Trajectories for Diabetic Polyneuropathy

Estimating Risk Factors and Trajectories for Diabetic Polyneuropathy

Investigators examined cardiometabolic risk factor trajectories in patients diagnosed with type 2 diabetes over the course of 13 years preceding diabetic polyneuropathy.

Young Cancer Survivors Have High Risk of Endocrine Diseases

Young Cancer Survivors Have High Risk of Endocrine Diseases

Adolescent and young adult cancer survivors have a 73 percent higher risk of endocrine diseases.

Health Coverage Interruptions Common in Adults With T1DM

Health Coverage Interruptions Common in Adults With T1DM

Interruptions in private health insurance coverage are common among U.S. adults with type 1 diabetes and are associated with an increase in glycated hemoglobin and in use of acute care services.

G6 CGM System Offers Improved Accuracy in Youth and Adults With Diabetes

G6 CGM System Offers Improved Accuracy in Youth and Adults With Diabetes

Investigators evaluate the performance of the G6 factory-calibrated continuous glucose monitoring system over 10 days.

Risk for Heart Failure Up in ALVSD Patients With Diabetes

Risk for Heart Failure Up in ALVSD Patients With Diabetes

For patients with asymptomatic left ventricular systolic dysfunction (ALVSD), those with diabetes have increased risk of heart failure development and hospitalization.

Diabetes Diagnosis May Impact Health Behaviors of Family

Diabetes Diagnosis May Impact Health Behaviors of Family

Partners of people with newly diagnosed diabetes have small but significant differences in health-related behavioral changes compared with partners of people without diabetes.

Ectopic Lipid Deposition and Insulin Resistance Higher in Postmenopausal Women

Ectopic Lipid Deposition and Insulin Resistance Higher in Postmenopausal Women

The insulin sensitivity in post- and premenopausal women along with lipid deposition in the liver and skeletal muscle was examined.

Detecting and Treating Depression in Diabetes

Detecting and Treating Depression in Diabetes

Comorbid depression, when not well controlled, can affect one's ability to self-manage diabetes. There can be loss of interest in making proper lifestyle choices, monitoring glucose levels, and taking one's medicines.

FDA Approves FreeStyle Libre 14 Day Flash Glucose Monitoring System

FDA Approves FreeStyle Libre 14 Day Flash Glucose Monitoring System

The new Flash Glucose Monitoring System enables patients to wear the sensor for up to 14 days compared with the existing FreeStyle Libre System that was approved for 10-day wear.

Hippocampal Calcification Associated With Aging, Diabetes, and Smoking

Hippocampal Calcification Associated With Aging, Diabetes, and Smoking

Investigators aim to identify risk factors for hippocampal calcifications and to investigate the relationship between hippocampal calcifications and cognitive function.

Masked High Blood Pressure and Arterial Stiffness in Type 1 Diabetes

Masked High Blood Pressure and Arterial Stiffness in Type 1 Diabetes

Ambulatory blood pressure monitoring in addition to office readings may effectively be able to identify individuals who are at high risk for CVD in T1D.

Anti-Thymocyte Globulin Reduced HbA1C in Newly Diagnosed Type 1 Diabetes

Anti-Thymocyte Globulin Reduced HbA1C in Newly Diagnosed Type 1 Diabetes

Investigators examined the effects of antithymocyte globulin with or without pegylated granulocyte colony-stimulating factor on β-cell function and HbA1C.

Risk for Diabetic Retinopathy With Incretin-Based Therapies

Risk for Diabetic Retinopathy With Incretin-Based Therapies

Investigators examined whether incretin-based therapies increase the risk for diabetic retinopathy compared with other antihyperglycemic agents.

Second-Line Sulfonylurea Therapy Linked to Cardiovascular Events in Type 2 Diabetes

Second-Line Sulfonylurea Therapy Linked to Cardiovascular Events in Type 2 Diabetes

Researchers assessed whether adding or switching to sulfonylureas is linked to increased risk for myocardial infarction, ischemic stroke, hypoglycemia, and all-cause mortality.

Diabetic Retinopathy May Be Independent Risk Factor for Parkinson Disease

Diabetic Retinopathy May Be Independent Risk Factor for Parkinson Disease

Results support that there is a relationship between diabetic retinopathy and Parkinson disease.

Characteristics of Severe Hypoglycemia Identified in T2DM

Characteristics of Severe Hypoglycemia Identified in T2DM

For patients with type 2 diabetes, characteristics of those with severe hypoglycemia include having a prior diagnosis of non-severe hypoglycemia and hemoglobin A1c (HbA1c) <6 percent.

PM2.5 Contributes to Burden of Diabetes Mellitus Globally

PM2.5 Contributes to Burden of Diabetes Mellitus Globally

Particulate matter (PM) with a diameter of less than 2.5 micrograms per cubic meter of air (PM2.5) makes a substantial contribution to the burden of diabetes.

Basal Insulin Analogs for Type 2 Diabetes Are Similar in Efficacy

Basal Insulin Analogs for Type 2 Diabetes Are Similar in Efficacy

A meta-analysis was conducted to examine the safety and efficacy of basal insulin analogs for type 2 diabetes.

Trulicity Labeling Updated to Include Data on T2D Patients With CKD

Trulicity Labeling Updated to Include Data on T2D Patients With CKD

In the AWARD-7 trial, patients who received Trulicity 0.75mg or 1.5mg in combination with mealtime insulin lispro achieved similar glycemic control with weight loss vs patients who received traditional basal-bolus insulin.

New Data Support Long-Term Cardiovascular Safety of Linagliptin in T2D

New Data Support Long-Term Cardiovascular Safety of Linagliptin in T2D

Results showed the overall safety profile of linagliptin in study patients, including adults with kidney disease, was consistent with previous data.

Severe Hypoglycemia in Type 2 Diabetes Linked to Poor Cognitive Outcomes

Severe Hypoglycemia in Type 2 Diabetes Linked to Poor Cognitive Outcomes

Adjustment of glucose-lowering medications in patients who are at high-risk for severe hypoglycemia may be beneficial to prevent mild cognitive impairment.

Canagliflozin Trial for T2D With CKD Stopped Early Due to Positive Results

Canagliflozin Trial for T2D With CKD Stopped Early Due to Positive Results

A clinical trial assessing canagliflozin (Invokana; Janssen) as an addition to standard-of-care in patients with chronic kidney disease (CKD) and type 2 diabetes (T2D) has been stopped early after meeting its pre-specified efficacy criteria.

Impact of a Longer Work Week on Diabetes Incidence

Impact of a Longer Work Week on Diabetes Incidence

A team of Canadian researchers sought to determine if working at least 45 hours per week had an effect on the incidence of diabetes.

Circadian System, Misalignment Have Distinct Impact on Insulin

Circadian System, Misalignment Have Distinct Impact on Insulin

The endogenous circadian system, behavioral cycle, and circadian misalignment have distinct effects on insulin sensitivity and β-cell function.

Impact of Maternal Diabetes on Outcomes in Very Preterm, Very Low-Birth-Weight Infants

Impact of Maternal Diabetes on Outcomes in Very Preterm, Very Low-Birth-Weight Infants

A retrospective cohort study was conducted to assess the relationship between maternal diabetes and morbidity/mortality in preterm infants.

Popliteal Sciatic Nerve Block May Increase Time to First Opioid Request in Diabetic Peripheral Neuropathy

Popliteal Sciatic Nerve Block May Increase Time to First Opioid Request in Diabetic Peripheral Neuropathy

Patients with type 2 diabetes and diabetic peripheral neuropathy may have an increased time to first opioid request and reduced time to onset of sensory blockade after an ultrasound-guided popliteal sciatic nerve block compared with patients without neuropathy.

Favorable Outcomes With Second-Generation Insulin Analogs in Type 2 Diabetes

Favorable Outcomes With Second-Generation Insulin Analogs in Type 2 Diabetes

A retrospective, observational study was conducted to assess outcomes in patients with type 2 diabetes treated with second-generation basal insulin analogs.

Travel Costs Are Considerable Part of T2DM Follow-Up Costs

Travel Costs Are Considerable Part of T2DM Follow-Up Costs

For patients with type 2 diabetes mellitus (T2DM), travel costs relating to hemoglobin A1c (HbA1c) screening constitute a substantial cost item, and self-monitoring can reduce costs.

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