Acarbose, an α-glucosidase inhibitor, decreased the incidence of diabetes in a population with impaired glucose tolerance who were at low risk of cardiovascular events.
Metformin is linked to a lower dementia risk compared to sulfonylureas among veterans with type 2 diabetes.
Researchers evaluated a meta-analysis of randomized controlled trials and an analysis of the FDA AE Reporting System to determine whether combination DPP4i/SGLT2i medication lowers risk of GUTI.
All dosages of oral semaglutide reduced mean HbA1c level significantly more than placebo by week 26.
People with type 2 diabetes and NOCS-NSTEMI who used incretin had a better prognosis than non-incretin users.
Among patients with schizophrenia, documented drug abuse and low contact volume of the diabetes clinic were associated with low-quality diabetes care.
A study confirms whether severe hypoglycemia increases risk for all-cause mortality in patients with type 2 diabetes.
Study revealed heterogeneity in plasma glucose response to oral glucose intake beyond the established glucose criteria based on fasting plasma glucose and 2 h post-load plasma glucose levels.
Lower incidence of microalbuminuria was noted with the use of ACE inhibitors vs placebo.
Study finds for the first time that during pregnancy the associations between serum 25OHD concentration and 2 single nucleotide polymorphisms are stronger in mothers of children with T1D.
Researchers assessed the impact of maternal gestational diabetes on insulin resistance and adiposity in adolescent offspring.
Professional continuous glucose monitoring can significantly reduce the economic burden of type 2 diabetes.
Adapting open-loop settings that are used by the artificial pancreas algorithm is easily understandable and transparent to both patients and physicians.
With this statement, researchers hope to improve safety and efficacy outcomes, advance technology, and improve patient quality of life and health outcomes.
Undiagnosed diabetes is a relatively small fraction of the total diabetes population when a confirmatory definition is used.
Second-line treatments are often initiated without first using first-line therapies.
Studies have not previously examined long-term risks or mortality after aortic aneurysm or dissection in people with type 2 diabetes.
Higher magnesium intake was linked to a 15% lower risk for type 2 diabetes.
Retinal sensitivity, assessed by microperimetry, is related to brain neurodegeneration in T2D.
Diabetes following pancreatic disease often requires higher use of insulin and worse glycemic control.
Study highlights the need to examine the safety of new glucose-lowering treatments specifically in patients with diabetes and heart failure and reduced ejection fraction.
People with T2D experienced greater HbA1c reductions with the addition of a DPP4 inhibitor vs placebo.
A recent population-based study is the first to examine the risk of type 2 diabetes associated with the use of antidepressant medication in children and adolescents.
Based on glycemic control and treatment method, type 2 diabetes in the heart failure population can be indicative of various risk associations.
Heart failure prevention may be an opportunity to reduce the risk of death in specific cardiovascular subcategories.
The new formulation of Bydureon BCise allows for once-weekly administration with an autoinjector pen.
The efficacy of liraglutide therapy was examined in metformin-treated subjects with obesity.
Greater prognostic advantages were associated with high-dose beta blockers in chronic heart failure with diabetes.
Overall reduction in HbA1c was higher in people with T2D vs those with T1D.
HbA1c, fasting plasma glucose, and body weight were significantly reduced in all patients taking tofogliflozin.
Ten-year heart failure outcomes were worse in patients with diabetes than without.
Daily financial incentives improved glucose monitoring, but not glycemic control.
With a little communication, children with diabetes can still enjoy Halloween festivities.
Twenty-five percent of people with type 2 diabetes and 12% of people with type 1 diabetes had depression.
The update provides guidance within 7 areas of type 2 diabetes management, including patient centered care and individualized treatment plans.
The latest ADA hypertension position statement incorporates advances in care since 2003.
PCSK9 inhibition with evolocumab might be an attractive therapy in patients with diabetes, and no discernible effect on glycaemia.
However, sulfonylurea plus insulin was linked to more hypglycemic events than insulin alone.
Referral to a commercial weight management program, such as Weight Watchers, can be effective in preventing diabetes.
Caffeine consumed from coffee or tea impacted both cardiovascular and cancer-related mortality in women with diabetes.
Although the incidence of severe hypoglycemia has decreased while insulin pump use has increased, a causal relationship has not been established between insulin administration methods and risk of complications from diabetes.
Painful diabetic neuropathy affects approximately one-quarter of people with diabetes.
Researchers have identified lasting benefits for patients with severe obesity who undergo Roux-en-Y gastric bypass surgery.
Although continuous glucose monitoring accuracy and safety in preterm infants has been validated in several studies, this approach has never been studied in neonates.
For medicare recipients it is more common to be overtreated than undertreated for diabetes.
One clinic shares results after replacing magazines with tablets allowing patients to examine their risk of developing diabetes.
Patients with prediabetes who experienced intensive blood pressure management had better outcomes with CVD events and all-cause mortality.
Liraglutide plus usual care resulted in lower rates of diabetic kidney disease-specific outcomes in type 2 diabetes.
Secure messaging presents an opportunity for patients and healthcare providers to collaborate on self-management issues like glycemic control, diet, and exercise.
Results indicate that blood glucose monitoring should be conducted in hospitalized patients with diabetes.
Researchers identified several novel plasma biomarkers that can be used to predict rapid decline in renal function in T2D, independent of traditional risk factors.
Clinicians should identify barriers to patient participation in diabetes self-management classes.
Results suggest that medication adherence is associated with reduced risk of all-cause mortality in T2D.
BMI measurement alone can also be used to determine associations between childhood and adulthood conditions.
The efficacy and safety profile of hyperbaric oxygen therapy remains controversial because of conflicting data and small sample sizes in clinical trials.
Subcutaneous exendin is safe and effective in treating post-bariatric hypoglycemia.
Validation-tool identified "high risk" patients were more likely to report hypoglycemia episodes and subsequent emergence department use.
Diabetes in infancy has different characteristics depending on mutation subtype, and is associated with high frequency of diabetic ketoacidosis.
There is reduced mortality for patients with diabetes undergoing RYGB.
The efficacy of diagnosing diabetes or prediabetes using fasting plasma glucose vs traditional HbA1c test was examined.
There is improved neonatal outcomes for pregnant women with T1D who use CGM.
Learn about strategies to reduce a patient's reluctance to initiate insulin therapy, a phenomenon called psychological insulin resistance.
The study included over 45,000 children using second-generation antipsychotic medications between 2009 and 2013.
The prescribing information for Afrezza has been updated to include new clinical data relating to treatment effect and dosing.
Patients with type 2 diabetes and those with diabetes secondary to chronic pancreatitis have similarly impaired α-cell responses to oral glucose ingestion and hypoglycemia.
Only about 60% of women with newly diagnosed gestational diabetes mellitus perform ≥80% of required self-monitoring of blood glucose tests.
Amyloid polypeptide deposits in the pancreas may lead scientists to a better understanding of type 2 diabetes.
Peptide immunotherapy may offer a personalized approach to modulating the immune response in persons with type 1 diabetes.
New monitoring system involves the placement of a small sensor wire beneath the skin surface to continuously monitor glucose levels.
Type 2 diabetes is significantly underdiagnosed and undertreated in patients with rheumatoid arthritis.
Hyperglycemia treatment was left to physician's discretion.
Approved in June 2017, the Humalog Junior KwikPen will soon be available to treat patients with diabetes.
Patients with MACE showed a greater extent of more severe coronary artery disease.
Researchers examined how adipocyte size reduction and fatty acid metabolism contribute to remission in type 2 diabetes following bariatric surgery.
Diacerein was well-tolerated among trial participants, and may be an acceptable adjunct treatment in type 2 diabetes.
Three hundred physically inactive or sedentary patients received either theoretical and practical counseling once-yearly for 3 years, or standard care.
PCI has been linked to increased risk of CHD, mortality, MI, and repeat revascularization in type 1 diabetes.
The 2009 H1N1 swine flu pandemic has been linked to an increased risk of new-onset type 1 diabetes in children.
Glycemic Control in Physically Active Adolescents With T1D: Closed-Loop Control vs Remote Pump in Winter Sports
During a 5-day ski camp, researchers examined closed-loop insulin management vs a remote monitored pump system for glycemic control with the additional challenge of cold and altitude.
More awareness for afib risk factors including age, severity of complications, and glycemic status are needed.
Researchers identified strong inverse graded relationships between children's sleep duration, adiposity, and the presence of diabetes risk markers.
The ADA 2017 Standards of Medical Care in Diabetes focuses on monitoring and pharmacologic approaches for type 1 diabetes management.
A retrospective analysis examined outcomes in patients with type 2 diabetes treated with SGLT2 vs DPP4 inhibitors.
Weight loss in people with type 2 diabetes is associated with extended life expectancy.
Researchers created body size phenotypes, defined by BMI category, to assess CVD incidence in a metabolically healthy obese population.
Women with atrial fibrillation and diabetes had a higher risk for mortality and cardiovascular complications compared with men.
Researchers examined the efficacy of cognitive behavioral group therapy on preventing weight regain or modifying cardiovascular risk factors and psychological well-being.
Worsening glycemic status is linked to increased reports of individual cardiorespiratory symptoms, including dyspnea, cough, chest pain, and arrythmia.
High-risk genotypes represent 6.4% of the included study population, but accounted for 61% of all cases of T1D.
Among women with polycystic ovary syndrome, type two diabetes was more common and diagnosed at a younger age than in control groups.
Study results support an additional management method for glycemic control in patients with T2D.
Researchers examined the efficacy of lifestyle intervention on glycemic control in type 2 diabetes.
Over 150 variables were identified as possible hypoglycemia risk factors.
An early invasive strategy in patients with non-ST-elevation acute coronary syndromes does not necessarily reduce mortality compared with a delayed strategy.
Updated meta-analysis confirms the association between antidepressant drug (AD) use and incident diabetes. Future studies should be aimed at evaluating the effect of single AD on the risk of developing T2D.
Serum NT-proBNP and serum hsTnl levels were examined at baseline, 26, 52, and 104 weeks.
Ipragliflozin showed "equally beneficial effects" on glycemic control in patients with nonalcoholic fatty liver disease and type 2 diabetes.
GlaxoSmithKline expects Tanzeum supplies to be depleted by July 2018.
Approval for the new indication follows a review of the results of the LEADER trial.
Ten randomized controlled trials were examined to determine the efficacy and safety of glyburide vs insulin treatment for gestational diabetes.
Endocrinology Advisor Articles
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- Insulin Glargine Associated With Breast Cancer Risk in T2D
- High Grip Strength Associated With Lower Risk for Diabetes-Related AEs
- Update on Vitamin D and Calcium Supplements for Reducing Fracture Risk
- Lower Risk for SGLT2i-Associated Genitourinary Infection With DPP-4i
- Bariatric Surgery: An Effective Treatment for Type 2 Diabetes
- Severe Hypoglycemia Associated With Increased Mortality Risk in T2D
- Efficacy of CGM in Preterm Infants of Mothers With Diabetes
- Increased Risk of Diabetes, Post-Diabetes Pneumonia for Patients With COPD
- Pancreatic Exocrine Dysfunction Occurs After Islet Autoimmunity in T1D
- T2D in African American Women Ups ER-negative Breast Cancer Risk
- High-Sensitivity CRP and LDL-C Predictive of Subsequent MACE in T2D
- Risks Associated With Denosumab Discontinuation