ADD THIS DRUG TO MY LIST

Select the drug indication to add to your list

DEPO-PROVERA CI
Contraception
Compare To Related Drugs
View/Edit/Compare Drugs In My List

Only 4 drugs may be compared at once

Drug Name:

DEPO-PROVERA CI Rx

Generic Name and Formulations:
Medroxyprogesterone acetate 150mg/mL; IM inj.

Company:
Pfizer Inc.

Therapeutic Use:

Indications for DEPO-PROVERA CI:

Injectable contraception.

Adult:

Give by deep IM inj in the gluteal or deltoid muscle; rotate inj sites. 150mg every 3 months. Give 1st dose within 5 days of onset of normal menses (see full labeling for postpartum). Do not use for >2 years unless other methods are inadequate.

Children:

Pre-menarche: not applicable.

Contraindications:

Active thrombophlebitis. Thromboembolic disorders. Cerebrovascular disease. Breast carcinoma. Significant liver disease. Undiagnosed vaginal bleeding. Pregnancy.

Warnings/Precautions:

Risk of bone mineral density (BMD) loss. Evaluate BMD with long-term use or in adolescents. Risk of osteoporosis (eg, metabolic bone disease, anorexia, family history). Family history of breast cancer or who have breast nodules (monitor closely). History of depression; monitor and do not re-administer if recurs. Diabetes. Conditions aggravated by fluid retention (eg, migraine, epilepsy, asthma). Cardiac or renal dysfunction. Pretreatment physical exam should include Pap smear and lab tests. Discontinue if jaundice or liver dysfunction, visual disturbances, migraine, or thrombotic disorders occur. Nursing mothers.

Interactions:

May be antagonized by aminoglutethimide, CYP3A4 inducers (eg, barbiturates, bosentan, carbamazepine, felbamate, griseofulvin, oxcarbazepine, phenytoin, rifampin, St. John's wort, topiramate). May reduce bone mass with anticonvulsants, corticosteroids; avoid alcohol, tobacco. May be affected by protease inhibitors, NNRTIs. May affect results of lab tests (eg, coagulation factors, lipids, glucose tolerance, and binding proteins); see full labeling.

See Also:

DEPO-SUBQ PROVERA

Pharmacological Class:

Progestin.

Adverse Reactions:

Menstrual irregularities (eg, bleeding, amenorrhea, spotting), abdominal pain/discomfort, weight gain, dizziness, headache, nervousness, decreased libido; decreased BMD, ectopic pregnancy, acne, inj site reactions (eg, pain/tenderness, persistent atrophy/indentation/dimpling, nodule/lump).

How Supplied:

Vials—1, 25; Prefilled syringes (1mL)—1 (w. needles); SubQ (prefilled syringe)—1 (w. needles)

Sign Up for Free e-Newsletters

CME Focus