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CASODEX
Prostate and other male cancers
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Drug Name:

CASODEX Rx

Generic Name and Formulations:
Bicalutamide 50mg; tabs.

Company:
AstraZeneca Pharmaceuticals

Therapeutic Use:

Indications for CASODEX:

In combination with luteinizing hormone-releasing hormone (LHRH) analogue in stage D2 metastatic prostate carcinoma.

Adult:

Take at the same time each day. 50mg daily. Start treatment at same time as starting LHRH analogue.

Children:

Not applicable.

Contraindications:

Women. Pregnancy.

Warnings/Precautions:

Moderate to severe hepatic impairment. Monitor prostate specific antigen and hepatic function (discontinue if ALT >2xULN or if jaundice occurs). Males with female partners of reproductive potential should use effective contraception during therapy and for 130 days after final dose. Nursing mothers.

Interactions:

Monitor oral anticoagulants.

Pharmacological Class:

Antiandrogen.

Adverse Reactions:

Hot flashes, gynecomastia, breast pain, diarrhea, pain, asthenia, infection, dyspnea, impotence, loss of libido, others (see full labeling); rare: hepatitis.

How Supplied:

Tabs—30, 100

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