USPSTF Draft Recommendations on Lipid Screening, Statin Use Open for Comment

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The USPSTF draft recommendations for lipid screening in children and statin use for adults are open for comment.
The USPSTF draft recommendations for lipid screening in children and statin use for adults are open for comment.

(HealthDay News) — The U.S. Preventive Services Task Force (USPSTF) has found that current evidence is insufficient for determining the balance of benefits and harms of lipid disorder screening in children, while for statin use in adults, recommendations vary with patient age. 

These findings form the basis of two draft recommendation statements published online December 21, 2015, by the USPSTF.

Researchers from the USPSTF reviewed the literature relating to screening for lipid disorders in children and adolescents younger than 20 without a known diagnosis of a lipid disorder. The researchers found that the current evidence was insufficient and the balance of benefits and harms of screening for lipid disorders could not be determined (I statement).

Researchers reviewed the literature relating to statin use for primary prevention of cardiovascular disease (CVD) in adults. The researchers recommended use of a low- to moderate-dose statin for CVD prevention for adults aged 40 to 75 years with at least 1 CVD risk factor and a 10-year cardiovascular event risk of at least 10% (B recommendation). 

For patients with a 7.5% to 10% risk for 10-year CVD event, the recommendation depends on the individual patient's situation (C recommendation). For adults aged at least 76 years without history of heart attack or stroke, the current evidence is insufficient to assess the balance of benefits and harms of statin use for CVD event prevention (I statement).

These findings form the basis of 2 draft recommendation statements, which are available for comment from December 22, 2015, to January 25, 2016.

References

  1. Draft Recommendation Statement: Lipid Disorders in Children and Adolescents: Screening. http://www.uspreventiveservicestaskforce.org/Page/Document/draft-recommendation-statement170/lipid-disorders-in-children-screening1. U.S. Preventive Services Task Force Web site. Published December 21, 2015. Accessed December 22, 2015.
  2. Chou R, Dana T, Blazina I, Daeges M, Bougatsos C, Jeanne T. Screening for Dyslipidemia in Younger Adults: Systematic Review to Update the 2008 U.S. Preventive Services Task Force Recommendation. http://www.uspreventiveservicestaskforce.org/Page/Document/draft-evidence-review138/statin-use-in-adults-preventive-medication1. U.S. Preventive Services Task Force Web site. Published December 21, 2015. Accessed December 22, 2015.
  3. Draft Recommendation Statement Statin Use for the Primary Prevention of Cardiovascular Disease in Adults: Preventive Medication. http://www.uspreventiveservicestaskforce.org/Page/Document/draft-recommendation-statement175/statin-use-in-adults-preventive-medication1. U.S. Preventive Services Task Force Web site. Published December 21, 2015. Accessed December 22, 2015.
  4. Chou R, Dana T, Blazina I, Daeges M, Bougatsos C, Jeanne T. Statins for Prevention of Cardiovascular Disease in Adults: Systematic Review for the U.S. Preventive Services Task Force. http://www.uspreventiveservicestaskforce.org/Page/Document/draft-evidence-review-statin-use-for-the-prevention-of-cardi/statin-use-in-adults-preventive-medication1. U.S. Preventive Services Task Force Web site. Published December 21, 2015. Accessed December 22, 2015.
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