Cardiovascular and Metabolic Disorders Feature Archive

Cross-Sex Hormone Therapy: What Are the Long-Term Risk Factors?

Cross-Sex Hormone Therapy: What Are the Long-Term Risk Factors?

Primary prevention of cardiovascular disease through risk factor modification, including tobacco cessation, maintenance of a body mass index, and management of abnormal lipid levels, diabetes, and hypertension, is of great importance for the health of transgender individuals.

Thyroid Dysfunction Not a Risk Factor for Carotid Plaque Development

Thyroid Dysfunction Not a Risk Factor for Carotid Plaque Development

Subclinical thyroid dysfunction did not influence the cumulative incidence of new carotid plaques in healthy individuals aged 20 or older.

Maternal Deaths in the United States: Sounding a Call to Action

Maternal Deaths in the United States: Sounding a Call to Action

Despite multiple measures and goals to reduce US maternal mortality rates, the latest data suggest the United States is far behind the rest of the world in maternal health care.

AACE, ACE Dyslipidemia Clinical Practice Guidelines Update

AACE, ACE Dyslipidemia Clinical Practice Guidelines Update

The new guidelines call for treating low-density lipoprotein cholesterol in specific patient groups to lower goals than previously recommended.

Polypharmacy and Lipid Profiles in Type 2 Diabetes

Polypharmacy and Lipid Profiles in Type 2 Diabetes

Even if the impact of a given medication on lipid profile is relatively minimal, and therefore unlikely to independently affect ASCVD risk, the cumulative effect is important and cannot be overlooked.

Role of Sodium Intake in Preventing Hypertension

Role of Sodium Intake in Preventing Hypertension

A recent investigation found that very low sodium intake may actually increase the risk for CVD and mortality.

Reviewing Treatment for Nonalcoholic Fatty Liver Disease

Reviewing Treatment for Nonalcoholic Fatty Liver Disease

A range of pharmacologic agents have a potential role in the management of NAFLD.

Activity Trackers With Financial Incentives Yielded No Improvements in Health

Activity Trackers With Financial Incentives Yielded No Improvements in Health

Even the addition of a cash incentive did not result in significant health benefits for patients using activity trackers.

SUSTAIN-6: Cardiovascular Safety of Semaglutide in Type 2 Diabetes

SUSTAIN-6: Cardiovascular Safety of Semaglutide in Type 2 Diabetes

Researchers found the cardiovascular safety of semaglutide was noninferior to placebo in high-risk patients with type 2 diabetes.

Did Industry Downplay Research Linking Sugar and CHD?

Did Industry Downplay Research Linking Sugar and CHD?

A historical analysis shows the Sugar Research Foundation may have influenced a review from Harvard researchers that downplayed the risks of sugar.

The Mediterranean Diet: What Are the Benefits?

The Mediterranean Diet: What Are the Benefits?

Adhering to the Mediterranean diet may stave off certain diseases, but the benefit on mortality remains questionable.

Assessing the Impact of Postmenopausal Hormone Therapy on Cardiovascular Health

Assessing the Impact of Postmenopausal Hormone Therapy on Cardiovascular Health

In light of ELITE trial results, estradiol hormone therapy may have a role in coronary heart disease treatment.

LEADER: Liraglutide Decreased Rate of CV Events in High-Risk Type 2 Diabetes

LEADER: Liraglutide Decreased Rate of CV Events in High-Risk Type 2 Diabetes

Compared with placebo, liraglutide decreased the rate of cardiovascular events in high-risk patients with diabetes.

SGLT2 Inhibitors: A Class Effect?

SGLT2 Inhibitors: A Class Effect?

Data on cardiovascular benefits as well as adverse effects have thrust this class of diabetes drugs into the spotlight.

Life Expectancy Gap Between Patients With Type 1 Diabetes and General Population Persists

Life Expectancy Gap Between Patients With Type 1 Diabetes and General Population Persists

Patients with diabetes not only had shorter life expectancy but also lived with disabilities longer than the general population.

HOPE-3: Blood Pressure, Cholesterol Lowering Evaluated in Intermediate-Risk Patients

HOPE-3: Blood Pressure, Cholesterol Lowering Evaluated in Intermediate-Risk Patients

Results from HOPE-3 suggest statins can be more widely used in intermediate-risk patients without cardiovascular disease.

Physical Activity Deficiency: A New Risk Factor for Type 2 Diabetes?

Physical Activity Deficiency: A New Risk Factor for Type 2 Diabetes?

Sedentary behaviors may boost risk for type 2 diabetes by 22% and risk for metabolic syndrome by 39%.

Cardiovascular Safety Results for Obesity Drug Inconclusive; Researchers Call for New Trial

Cardiovascular Safety Results for Obesity Drug Inconclusive; Researchers Call for New Trial

Findings did not establish the prespecified margin of noninferiority after unplanned early termination.

Evaluating the Link Between Cardiovascular Disease and Depression

Evaluating the Link Between Cardiovascular Disease and Depression

Patients with cardiovascular disease are 3 times more likely to develop depression, which makes psychosocial health monitoring essential.

Exercise for Prevention of Heart Disease

Exercise for Prevention of Heart Disease

Exercise's potential positive effects on cardiovascular disease and heart failure may be possible regardless of frequency and time of initiation.

New Dietary Guidelines Receive Support, but Also Spark Controversy

New Dietary Guidelines Receive Support, but Also Spark Controversy

Although many clinicians applaud the big-picture approach of the new guidelines, some have taken issue with certain recommendations.

SPRINT Challenges Current Standard of Care for Patients Without Diabetes

SPRINT Challenges Current Standard of Care for Patients Without Diabetes

Results from the SPRINT trial, reported at the American Heart Association, suggest that lower systolic blood pressure targets may be more effective in lowering cardiovascular risk.

AACE/ACE Updates Algorithm for Type 2 Diabetes Management

AACE/ACE Updates Algorithm for Type 2 Diabetes Management

The American Association of Clinical Endocrinologists' updated algorithm for type 2 diabetes management addresses lifestyle modifications and obesity treatments.

Central Obesity May Raise Mortality Risk in Normal-Weight Individuals

Central Obesity May Raise Mortality Risk in Normal-Weight Individuals

Central obesity in people with normal weight may increase the risk for premature mortality vs BMI-defined overweight or obesity.

EMPA-REG: Empagliflozin Cut Heart Failure Hospitalizations, CV Death in High-Risk Diabetes Patients

EMPA-REG: Empagliflozin Cut Heart Failure Hospitalizations, CV Death in High-Risk Diabetes Patients

Results showed a consistent benefit in both patients with and those without heart failure.

Teen-LABS: Bariatric Surgery Beneficial for Adolescents After 3 Years

Teen-LABS: Bariatric Surgery Beneficial for Adolescents After 3 Years

Weight, metabolic health, and overall quality of life improved 3 years after bariatric surgery.

Blood Pressure Management During Stroke Remains Controversial

Blood Pressure Management During Stroke Remains Controversial

With no established guidelines, much of the decisions for management of hypertension during stroke are based on clinician experience.

PCSK9 Inhibitors Safe, Effective in Hypercholesterolemia

PCSK9 Inhibitors Safe, Effective in Hypercholesterolemia

PCSK9 antibodies can safely and effectively treat high cholesterol in adults while reducing mortality rates.

Improving Detection of Nonalcoholic Fatty Liver Disease

Improving Detection of Nonalcoholic Fatty Liver Disease

New imaging techniques show promise for diagnosing NAFLD.

Delving Deeper Into Lipids for Cardiovascular Risk Assessment

Delving Deeper Into Lipids for Cardiovascular Risk Assessment

The first step in reducing the risk for cardiovascular disease is for health care professionals to get a full understanding of a patient's risk.

New ACC/AHA Guidelines: Current Lipid Management in Diabetes

New ACC/AHA Guidelines: Current Lipid Management in Diabetes

The American College of Cardiology and American Heart Association guidelines prompt significant changes in lipid management.

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