Cardiovascular and Metabolic Disorders Archive
Researchers assessed the impact of maternal gestational diabetes on insulin resistance and adiposity in adolescent offspring.
Studies have not previously examined long-term risks or mortality after aortic aneurysm or dissection in people with type 2 diabetes.
Study highlights the need to examine the safety of new glucose-lowering treatments specifically in patients with diabetes and heart failure and reduced ejection fraction.
Based on glycemic control and treatment method, type 2 diabetes in the heart failure population can be indicative of various risk associations.
Heart failure prevention may be an opportunity to reduce the risk of death in specific cardiovascular subcategories.
Greater prognostic advantages were associated with high-dose beta blockers in chronic heart failure with diabetes.
The latest ADA hypertension position statement incorporates advances in care since 2003.
PCSK9 inhibition with evolocumab might be an attractive therapy in patients with diabetes, and no discernible effect on glycaemia.
Patients with prediabetes who experienced intensive blood pressure management had better outcomes with CVD events and all-cause mortality.
Results suggest that medication adherence is associated with reduced risk of all-cause mortality in T2D.
BMI measurement alone can also be used to determine associations between childhood and adulthood conditions.
Increasing obesity is associated with increased ICU resource utilization in patients undergoing cardiac surgery.
From 25% to 50% of patients discontinue statins within 6 months to 1 year of starting, and the rate increases as high as 75% after 2 years.
Increases in BMI z-score between 7 and 13 years of age increase a person's risk of ischemic stroke in early adulthood.
Hyperglycemia treatment was left to physician's discretion.
The American Academy of Pediatrics released an update to previous hypertension management updates published in 2004.
Patients with MACE showed a greater extent of more severe coronary artery disease.
PCI has been linked to increased risk of CHD, mortality, MI, and repeat revascularization in type 1 diabetes.
More awareness for afib risk factors including age, severity of complications, and glycemic status are needed.
A retrospective analysis examined outcomes in patients with type 2 diabetes treated with SGLT2 vs DPP4 inhibitors.
Researchers created body size phenotypes, defined by BMI category, to assess CVD incidence in a metabolically healthy obese population.
Women with atrial fibrillation and diabetes had a higher risk for mortality and cardiovascular complications compared with men.
Losing weight may result in a decrease of heart muscle thickness.
Patients treated with zoledronic acid vs oral bisphosphonates had higher risk for heart failure and arrhythmias.
An early invasive strategy in patients with non-ST-elevation acute coronary syndromes does not necessarily reduce mortality compared with a delayed strategy.
Multiple clinical studies have examined the efficacy of pitavastatin.
Researchers urge physicians to consider polygenic causes for patients with severe hypertriglyceridemia.
Researchers created 3 plant-based diet indices based on the healthiness of specific foods.
A newly released recommendation statement suggests that physicians should provide lifestyle counseling to both low- and high-risk adults to prevent CVD.
Further investigation is needed to examine the mechanism behind aspirin responsiveness following bariatric surgery.
Compared with insulin glargine, insulin degludec significantly reduced rates of hypoglycemia in patients with either type 1 or type 2 diabetes.
High-dose atorvastatin therapy can reduce inflammation and improve quality of life in patients with severe bronchiectasis and P aeruginosa infection.
Patients with type 2 diabetes who were initiated on insulin therapy increased their sitting time and decreased their low-intensity physical activity.
Dutasteride therapy for benign prostatic hyperlasia has been linked to elevated HbA1c and LDL cholesterol.
Researchers linked all major causes of mortality to childhood intelligence.
N-terminal pro-B-type natriuretic peptide showed the strongest association with heart failure in patients with type 2 diabetes.
Eighty-three veterans with PTSD participated in a study examining biological pathways between PTSD and metabolic diseases.
The least common condition, systemic lupus erythematosus, was associated with the highest association of experiencing multiple cardiometabolic events.
Over 37,000 men were tracked from ages 8 to 20 to examine the link between adolescent BMI and stroke risk.
Left ventricular function can be improved, but not normalized, in adolescents with type 1 diabetes.
Two-hour postload glucose better predicted cardiovascular events compared with fasting plasma glucose and HbA1c.
Metabolic Profile, Weight Increases Assessed in Ziprasidone Augmentation for Major Depressive Disorder
Escitalopram plus ziprasidone was found safe in certain patients, although the therapy required regular cardiovascular and metabolic monitoring.
Data from a UK cohort were used to examine the relationship between maternal sugar intake levels and pediatric respiratory and atopic outcomes.
Pregnancy-associated stroke risk is even higher in women with chronic hypertension, coagulopathies, and prothrombotic conditions.
Researchers examined the efficacy of aspirin in preventing preterm preeclampsia in women at risk.
Financial data for both mothers and children were examined through the first year of life.
Comorbidities included hyperlipidemia, hypertension, and type 2 diabetes, among others.
Extent and severity of coronary artery disease was examined in over 900 patients with type 2 diabetes.
Over 200 patients participated in the study of a novel immunoassay used to distinguish hypertension from hyperaldosteronism.
Sodium-glucose cotransporter 2 inhibitors reduced both systolic and diastolic blood pressure in patients with type 2 diabetes.
Statin and aspirin therapies in diabetes did not increased patients' risks of cardiovascular events.
Data from the 9300 patient LEADER trial is now eligible for inclusion on liraglutide injection packaging.
Patients with lower vitamin D levels had higher cIMT and were at elevated risk for cardiovascular conditions.
Although metformin did not improve glycemic control in patients with type 1 diabetes, the treatment did improve cardiovascular disease risk management.
Updates to the US Preventive Services Task Force's recommendations on obesity screening in children and adolescents focus on intensive behavioral interventions.
Widely promoted as healthy, coconut oil can increase LDL cholesterol levels similar to other saturated fats.
For patients with type 2 diabetes, visit-to-visit variability in systolic blood pressure may function as an independent predictor for cardiovascular events.
The most effective approaches to CVD self-management were tailored to individual patient needs and incorporated a multidisciplinary approach.
Researchers presented data from the ODYSSEY DM Insulin and Dyslipidemia trials at ADA 2017.
Cardiometabolic Disease Staging scores can be used to quantify diabetes risk and assess efficacy of weight loss pharmacotherapy in obesity.
According to Journal of the American Heart Association, pregnant women with chronic hypertension using antihypertensive agents reduces the risk of hypertension without added risk to the fetus.
The FDA is poised to review data from the DEVOTE trial, examining the rates of major adverse cardiovascular events in insulin degludec vs insulin glargine.
Patients with metabolic syndrome experienced an increase in Unified Parkinson's Disease Rating Scale (UPDRS) scores.
Researchers suggest that women with overweight or obesity aim to lose weight before becoming pregnant.
The role of cholesterol in Parkinson's disease is not well understood.
Two studies examined the effects of naltrexone/bupropion on weight loss, glycemic parameters, and cardiovascular risks in patients with type 2 diabetes.
Patients with type 2 diabetes taking statins after insulin initiation had better glycemic control, but their risk for mortality was higher compared with patients who did not take statins.
Riser patterns in patients' BP resulting from orthostatic hypotension has been linked to increased rates of mortality and major adverse cardiac and cerebrovascular events.
Low-Carbohydrate vs Low-fat Diet Success In Patients With Prediabetes Differs According to Fasting Insulin Levels
Fasting plasma glucose, insulin, and insulin sensitivity levels were measured to determine their prognostic value as markers for long-term weight loss.
Researchers conducted a subgroup analysis of the SPRINT clinical trial to determine whether intensive blood pressure treatment outcomes were similar in patients with prediabetes vs normal fasting blood glucose levels.
Canagliflozin reduced levels of cardiovascular stress biomarkers N-terminal pro-B type natriuretic peptide and high sensitivity troponin I.
Flow mediated dilation changes improved in patients who received dapagliflozin.
Sitagliptin improved glucose excursion and lowered triglyceride levels in men with prediabetes who were also overweight.
Interventions seeking to counteract antipsychotic-induced weight gain and cardiometabolic disturbances have had limited success.
Neonates did not differ in terms of birthweight, fat mass, body fat percentage, and sum of skinfolds, regardless of treatment.
Patients with cardiovascular disease and both type 2 diabetes and chronic kidney disease had the highest risk for mortality.
Resveratrol supplements were fount to activate the SIRT1 gene, which delays aging and the development of various diseases.
Patients with type 2 diabetes had lower rates of heart failure hospitalization, MACE, and all-cause mortality when treated with dapagliflozin.
Vitamin K antagonists and low-molecular weight heparin were associated with the lowest risks of adverse maternal and fetal outcomes.
Modest changes were recorded in patients' weight, fasting glucose, and glycated hemoglobin levels with long-term schizophrenia therapy.
Individuals with low BMI are not at an increased risk for Alzheimer disease.
Women with preeclampsia should heed any neurological symptoms, which may be signs of a stroke.
Long-term use of anabolic-androgenic steroids increases risks for decreased left ventricular diastolic function and increased coronary plaque volume.
Women at high risk for preeclampsia should take low-dose aspirin as a preventive therapy.
Age significantly affected the association between hot flash status and flow-mediated dilation, particularly in younger women.
The fewer menstrual cycles women had over a lifetime placed them at greater risk for incident heart failure.
A 37-year-old woman presented to the emergency department with recurrent dizziness following her recent pregnancy.
Cardiometabolic Comorbidities, Hospitalizations, and Costs Associated With Schizophrenia and Bipolar Disorder
People with schizophrenia or bipolar disorder experience twice the rate of diabetes and metabolic syndrome compared to the general population.
Researchers conducted a meta-analysis of 70 studies to analyze the prevalence of metabolic syndrome in patients with rheumatoid arthritis.
Use of thiazolidinediones reduced patient's risk of atrial fibrillation by 30%.
A common variant in the sulfonylurea receptor has been associated with a reduced risk of both type 2 diabetes and coronary heart disease.
Postbiotic reduced hepatic insulin resistance in obesity and low-level endotoxemia.
The relative risk for developing preeclampsia, determined using waist-to-hip ratio, was 3.317 vs 2.418 using BMI.
There has been growing concern that testosterone replacement therapy is associated with adverse cardiovascular outcomes.
More than 40% of adolescents had either prehypertension or hypertension.
Patients with comorbid congestive heart failure who received parenteral nutrition had higher mortality rates.
Patients with type 1 diabetes had higher mortality rates when admitted for acute myocardial infarction compared with patients with type 2 diabetes.
Findings suggest an inverse association between sodium intake and diastolic and systolic blood pressure levels.
As achieved glycated hemoglobin A1c levels increased, the risk for a combined cardiovascular event increased.
The highest prevalence of metabolic syndrome in women with polycystic ovary syndrome in the United States occurred in black women.
Endocrinology Advisor Articles
- Imaging Studies in Hypothyroidism Evaluation Linked to Unnecessary Risks
- Transoral Endoscopic Thyroidectomy Vestibular Approach: Safety and Outcomes
- Once-Weekly Omarigliptin Improves Glycemic Control in Type 2 Diabetes
- Insulin Glargine Associated With Breast Cancer Risk in T2D
- High Grip Strength Associated With Lower Risk for Diabetes-Related AEs
- Update on Vitamin D and Calcium Supplements for Reducing Fracture Risk
- Lower Risk for SGLT2i-Associated Genitourinary Infection With DPP-4i
- Bariatric Surgery: An Effective Treatment for Type 2 Diabetes
- Severe Hypoglycemia Associated With Increased Mortality Risk in T2D
- Efficacy of CGM in Preterm Infants of Mothers With Diabetes
- Increased Risk of Diabetes, Post-Diabetes Pneumonia for Patients With COPD
- Pancreatic Exocrine Dysfunction Occurs After Islet Autoimmunity in T1D
- T2D in African American Women Ups ER-negative Breast Cancer Risk
- High-Sensitivity CRP and LDL-C Predictive of Subsequent MACE in T2D
- Risks Associated With Denosumab Discontinuation