Cardiovascular and Metabolic Disorders Archive

Plasma Volume Changes Mediate Risk of CV Mortality With Empagliflozin

Plasma Volume Changes Mediate Risk of CV Mortality With Empagliflozin

The reduction in risk of cardiovascular death with empagliflozin is most mediated by changes in hematocrit and hemoglobin.

Higher Risk for Stroke, MI in Patients With Gout, Diabetes

Higher Risk for Stroke, MI in Patients With Gout, Diabetes

Patients with both gout and diabetes are at a much higher risk for stroke and myocardial infarction than with diabetes alone.

Intensive Blood Pressure Lowering Reduces CV Events Similarly in Patients With/Without T2D

Intensive Blood Pressure Lowering Reduces CV Events Similarly in Patients With/Without T2D

Researchers assessed the effect of both type 2 diabetes and baseline cardiovascular disease risk on the treatment effect of intensive blood pressure lowering based on data and pooled analysis from 14,094 patients.

Subclinical Primary Aldosteronism Increases Hypertension Risk in Normotensive Patients

Subclinical Primary Aldosteronism Increases Hypertension Risk in Normotensive Patients

Future studies using a renin phenotype-driven approach may efficiently identify new-onset or mild hypertension.

CV Event Prediction, Risk Assessment in Type 2 Diabetes

CV Event Prediction, Risk Assessment in Type 2 Diabetes

Risk of cardiovascular events in people with type 2 diabetes and subgroups of coronary artery disease was examined.

Vascular Endothelial Dysfunction Involved in Hypertension Development in T1D

Vascular Endothelial Dysfunction Involved in Hypertension Development in T1D

A life-course study evaluated the contribution of vascular endothelial dysfunction and inflammation to the development of hypertension in type 1 diabetes.

Urinary Albumin-to-Creatinine Ratio Aids CV Risk Assessment in T2D

Urinary Albumin-to-Creatinine Ratio Aids CV Risk Assessment in T2D

Urinary albumin-to-creatinine ratio can be independently associated with various adverse CV outcomes.

Coronary Artery Bypass Grafting: Preferred Method of Revascularization in Diabetes

Coronary Artery Bypass Grafting: Preferred Method of Revascularization in Diabetes

In patients with diabetes, coronary artery bypass grafting may be the preferred method of revascularization, with lower rates of major adverse cardiac or cerebrovascular events.

Physical Activity, Sedentary Time May Increase Cardiometabolic Risk Markers in Prediabetes

Physical Activity, Sedentary Time May Increase Cardiometabolic Risk Markers in Prediabetes

A study sought to clarify whether total physical activity during the day is equally as important as achieving high levels of intensity associated with moderate-to-vigorous physical activity.

More Evidence That Saxagliptin Does Not Increase Risk for AMI in Diabetes

More Evidence That Saxagliptin Does Not Increase Risk for AMI in Diabetes

Patients with diabetes taking saxagliptin, sitagliptin, second-generation sulfonylureas, pioglitazone, and long-acting insulin were assessed for the risk of acute myocardial infarction.

Elderly Patients With T2D, Heart Failure Have High Risk for Mortality

Elderly Patients With T2D, Heart Failure Have High Risk for Mortality

A strong association was found in study between poor survival in elderly patients with type 2 diabetes and cardiovascular complications, especially heart failure.

Hypertensive Disorders During Pregnancy Increase Risk for Future CVD

Hypertensive Disorders During Pregnancy Increase Risk for Future CVD

Women with hypertensive disorders during pregnancy have a significantly greater risk for future cardiovascular disease when compared with normotensive expecting mothers.

Case Study: Man With Obesity, Hypertension Presenting With Worsening Palpitations

Case Study: Man With Obesity, Hypertension Presenting With Worsening Palpitations

A man presents to the emergency department having had palpitations for the past week, and he has a medical history of hypertension, obesity, and hyperlipidemia. What's the diagnosis?

CVD Hospitalization Rates in Diabetes Decreased in 1998-2014

CVD Hospitalization Rates in Diabetes Decreased in 1998-2014

Cardiovascular disease hospitalization rates have declined in recent years among individuals with and those without diabetes.

Higher Childhood BMI Associated With Adult Ischemic Stroke

Higher Childhood BMI Associated With Adult Ischemic Stroke

Higher childhood body mass index and increases in BMI during childhood are linked to an increased risk of early adult ischemic stroke.

Insulin-Induced Weight Gain Not Associated With Adverse CV Outcomes in T2D

Insulin-Induced Weight Gain Not Associated With Adverse CV Outcomes in T2D

Despite the well‐recognized correlation between weight gain and cardiovascular (CV) disease, there is little direct evidence relating to the impact of insulin‐induced weight gain on CV outcomes.

Stopping Postmenopausal HT May Increase Risk for Cardiac, Stroke Death

Stopping Postmenopausal HT May Increase Risk for Cardiac, Stroke Death

Increased mortality risks were limited to the first post-HT year because increases in risks markedly decreased when the follow-up time was extended over more than 1 year.

No Difference in Cardiovascular Outcomes With Exenatide vs Placebo in T2D

No Difference in Cardiovascular Outcomes With Exenatide vs Placebo in T2D

Once-weekly administration of extended-release exenatide in patients with T2D at a wide range of cardiovascular risk appeared not to cause an increase in their overall cardiovascular risk.

Empagliflozin Reduces CVD Risk in Patients With T2D and PAD

Empagliflozin Reduces CVD Risk in Patients With T2D and PAD

Empagliflozin lowered the risk of cardiovascular death vs placebo when added to standard of care in adults with both type 2 diabetes and peripheral artery disease.

High-Sensitivity CRP and LDL-C Predictive of Subsequent MACE in T2D

High-Sensitivity CRP and LDL-C Predictive of Subsequent MACE in T2D

Levels of high sensitivity C-reactive protein may help risk stratify those patients with T2D and recent acute coronary syndrome at further risk of recurrent cardiovascular events.

High Grip Strength Associated With Lower Risk for Diabetes-Related AEs

High Grip Strength Associated With Lower Risk for Diabetes-Related AEs

Grip strength has clinical utility in identifying people with diabetes at risk for poor health outcomes.

Statin Use for CVD Prevention Increases Diabetes Risk in Overweight Patients

Statin Use for CVD Prevention Increases Diabetes Risk in Overweight Patients

The association between statin use and diabetes risk in a cohort of overweight and obese patients was examined.

FDA Approves Drug for Mucopolysaccharidosis Type VII

FDA Approves Drug for Mucopolysaccharidosis Type VII

Mepsevii replaces beta-glucuronidase, the deficiency of which causes an abnormal buildup of toxic materials in the body's cells.

Postpartum Hypertension in Preeclampsia: Do Puerperal NSAIDs Effect Risk?

Postpartum Hypertension in Preeclampsia: Do Puerperal NSAIDs Effect Risk?

Investigators encourage further research on the use of NSAIDs in women with preeclampsia who develop postpartum hypertension.

Improving Vascular Function in Pediatric T1D With Metformin

Improving Vascular Function in Pediatric T1D With Metformin

Study aimed to determine the effect of metformin on vascular health in children with T1D and above average weight.

Acarbose Reduces Diabetes Risk in Coronary Heart Disease

Acarbose Reduces Diabetes Risk in Coronary Heart Disease

Acarbose, an α-glucosidase inhibitor, decreased the incidence of diabetes in a population with impaired glucose tolerance who were at low risk of cardiovascular events.

Improving NSTEMI Outcomes in T2D With NOCS: Efficacy of Incretin

Improving NSTEMI Outcomes in T2D With NOCS: Efficacy of Incretin

People with type 2 diabetes and NOCS-NSTEMI who used incretin had a better prognosis than non-incretin users.

Severe Hypoglycemia Associated With Increased Mortality Risk in T2D

Severe Hypoglycemia Associated With Increased Mortality Risk in T2D

A study confirms whether severe hypoglycemia increases risk for all-cause mortality in patients with type 2 diabetes.

Glucose Patterns and the Future Development of Diabetes

Glucose Patterns and the Future Development of Diabetes

Study revealed heterogeneity in plasma glucose response to oral glucose intake beyond the established glucose criteria based on fasting plasma glucose and 2 h post-load plasma glucose levels.

Gestational Diabetes Associated With Adiposity, Puberty Onset in Offspring

Gestational Diabetes Associated With Adiposity, Puberty Onset in Offspring

Researchers assessed the impact of maternal gestational diabetes on insulin resistance and adiposity in adolescent offspring.

Type 2 Diabetes Protective Against Aortic Aneurysm, Dissection

Type 2 Diabetes Protective Against Aortic Aneurysm, Dissection

Studies have not previously examined long-term risks or mortality after aortic aneurysm or dissection in people with type 2 diabetes.

Ventricular Function With Vildagliptin in T2D and CHF

Ventricular Function With Vildagliptin in T2D and CHF

Study highlights the need to examine the safety of new glucose-lowering treatments specifically in patients with diabetes and heart failure and reduced ejection fraction.

HbA1c Predictive of Poor Heart Failure Outcomes in T2D

HbA1c Predictive of Poor Heart Failure Outcomes in T2D

Based on glycemic control and treatment method, type 2 diabetes in the heart failure population can be indicative of various risk associations.

Sudden Death in T2D: Examining the Most Common Cause of CV Mortality

Sudden Death in T2D: Examining the Most Common Cause of CV Mortality

Heart failure prevention may be an opportunity to reduce the risk of death in specific cardiovascular subcategories.

High-Dose Beta-Blockers More Effective in Chronic Heart Failure, Diabetes

High-Dose Beta-Blockers More Effective in Chronic Heart Failure, Diabetes

Greater prognostic advantages were associated with high-dose beta blockers in chronic heart failure with diabetes.

ADA Position Statement Update: Hypertension Management in Diabetes

ADA Position Statement Update: Hypertension Management in Diabetes

The latest ADA hypertension position statement incorporates advances in care since 2003.

Evolocumab May Decrease Cardiovascular Risk in Patients With and Without Diabetes

Evolocumab May Decrease Cardiovascular Risk in Patients With and Without Diabetes

PCSK9 inhibition with evolocumab might be an attractive therapy in patients with diabetes, and no discernible effect on glycaemia.

SPRINT Update: Positive CVD Outcomes With Intensive Blood Pressure Management in Prediabetes

SPRINT Update: Positive CVD Outcomes With Intensive Blood Pressure Management in Prediabetes

Patients with prediabetes who experienced intensive blood pressure management had better outcomes with CVD events and all-cause mortality.

Examining Inclusion of T2D Medication Adherence Data in Studies

Examining Inclusion of T2D Medication Adherence Data in Studies

Results suggest that medication adherence is associated with reduced risk of all-cause mortality in T2D.

Predicting Adult MetS, T2D, CV Risks in Childhood

Predicting Adult MetS, T2D, CV Risks in Childhood

BMI measurement alone can also be used to determine associations between childhood and adulthood conditions.

ICU Resource Use After Cardiac Surgery Increased With Obesity

ICU Resource Use After Cardiac Surgery Increased With Obesity

Increasing obesity is associated with increased ICU resource utilization in patients undergoing cardiac surgery.

Statins Beneficial for High-Risk Patients Despite Adverse Reactions

Statins Beneficial for High-Risk Patients Despite Adverse Reactions

From 25% to 50% of patients discontinue statins within 6 months to 1 year of starting, and the rate increases as high as 75% after 2 years.

Stroke Risk Upped With High Childhood BMI

Stroke Risk Upped With High Childhood BMI

Increases in BMI z-score between 7 and 13 years of age increase a person's risk of ischemic stroke in early adulthood.

Following Ischemic Stroke, Glycemic Control Indicative of Short-Term Outcomes

Following Ischemic Stroke, Glycemic Control Indicative of Short-Term Outcomes

Hyperglycemia treatment was left to physician's discretion.

AAP: Updated Guidelines for Managing High Blood Pressure in Children

AAP: Updated Guidelines for Managing High Blood Pressure in Children

The American Academy of Pediatrics released an update to previous hypertension management updates published in 2004.

Predicting Coronary Artery Events in T2D With Imaging Plus Risk Factor Assessment

Predicting Coronary Artery Events in T2D With Imaging Plus Risk Factor Assessment

Patients with MACE showed a greater extent of more severe coronary artery disease.

Strategies for Multivessel Revascularization in T1D: CABG vs PCI

Strategies for Multivessel Revascularization in T1D: CABG vs PCI

PCI has been linked to increased risk of CHD, mortality, MI, and repeat revascularization in type 1 diabetes.

Cardiovascular, Renal Outcomes in Type 1 Diabetes

Cardiovascular, Renal Outcomes in Type 1 Diabetes

More awareness for afib risk factors including age, severity of complications, and glycemic status are needed.

Lowering Heart Failure Hospitalizations in T2D: SGLT2 vs DPP4 Inhibitors

Lowering Heart Failure Hospitalizations in T2D: SGLT2 vs DPP4 Inhibitors

A retrospective analysis examined outcomes in patients with type 2 diabetes treated with SGLT2 vs DPP4 inhibitors.

Population at Risk: CVD Events Increased in Metabolically Healthy Obese

Population at Risk: CVD Events Increased in Metabolically Healthy Obese

Researchers created body size phenotypes, defined by BMI category, to assess CVD incidence in a metabolically healthy obese population.

Atrial Fibrillation With Diabetes: Risk for Cardiovascular Events in Women vs Men

Atrial Fibrillation With Diabetes: Risk for Cardiovascular Events in Women vs Men

Women with atrial fibrillation and diabetes had a higher risk for mortality and cardiovascular complications compared with men.

Examined: Correlation Between Weight Increase and Heart Failure Risk

Examined: Correlation Between Weight Increase and Heart Failure Risk

Losing weight may result in a decrease of heart muscle thickness.

Cardiovascular Event Risks With Zoledronic Acid vs Oral Bisphosphonates

Cardiovascular Event Risks With Zoledronic Acid vs Oral Bisphosphonates

Patients treated with zoledronic acid vs oral bisphosphonates had higher risk for heart failure and arrhythmias.

Comparing Early, Delayed Invasive Strategy in Non-ST-Elevation Acute Coronary Syndromes

Comparing Early, Delayed Invasive Strategy in Non-ST-Elevation Acute Coronary Syndromes

An early invasive strategy in patients with non-ST-elevation acute coronary syndromes does not necessarily reduce mortality compared with a delayed strategy.

FDA Approves Pitavastatin for Hyperlipidemia, Mixed Dyslipidemia

FDA Approves Pitavastatin for Hyperlipidemia, Mixed Dyslipidemia

Multiple clinical studies have examined the efficacy of pitavastatin.

A Polygenic Risk for Severe Hypertriglyceridemia: Case Study

A Polygenic Risk for Severe Hypertriglyceridemia: Case Study

Researchers urge physicians to consider polygenic causes for patients with severe hypertriglyceridemia.

"Less Healthy" Plant Food Diet Associated With CHD Risk

"Less Healthy" Plant Food Diet Associated With CHD Risk

Researchers created 3 plant-based diet indices based on the healthiness of specific foods.

USPSTF: Lifestyle Counseling Can Protect CV Health in Low-Risk Adults

USPSTF: Lifestyle Counseling Can Protect CV Health in Low-Risk Adults

A newly released recommendation statement suggests that physicians should provide lifestyle counseling to both low- and high-risk adults to prevent CVD.

Improved Aspirin Responsiveness in Obesity With Bariatric Surgery

Improved Aspirin Responsiveness in Obesity With Bariatric Surgery

Further investigation is needed to examine the mechanism behind aspirin responsiveness following bariatric surgery.

Reducing Hypoglycemia in T1D and T2D: Insulin Degludec vs Insulin Glargine

Reducing Hypoglycemia in T1D and T2D: Insulin Degludec vs Insulin Glargine

Compared with insulin glargine, insulin degludec significantly reduced rates of hypoglycemia in patients with either type 1 or type 2 diabetes.

Improving Patient QoL With Atorvastatin in Bronchiectasis

Improving Patient QoL With Atorvastatin in Bronchiectasis

High-dose atorvastatin therapy can reduce inflammation and improve quality of life in patients with severe bronchiectasis and P aeruginosa infection.

Insulin Therapy Initiation in T2D Associated With Sedentary Behavior, Weight Increases

Insulin Therapy Initiation in T2D Associated With Sedentary Behavior, Weight Increases

Patients with type 2 diabetes who were initiated on insulin therapy increased their sitting time and decreased their low-intensity physical activity.

Metabolic Concerns With Dutasteride Therapy for BPH

Metabolic Concerns With Dutasteride Therapy for BPH

Dutasteride therapy for benign prostatic hyperlasia has been linked to elevated HbA1c and LDL cholesterol.

Childhood Intelligence Tied to Lower Cardiovascular Mortality

Childhood Intelligence Tied to Lower Cardiovascular Mortality

Researchers linked all major causes of mortality to childhood intelligence.

Heart Failure in Type 2 Diabetes: Improving the Risk Model

Heart Failure in Type 2 Diabetes: Improving the Risk Model

N-terminal pro-B-type natriuretic peptide showed the strongest association with heart failure in patients with type 2 diabetes.

High Risk of Insulin Resistance, PTSD Biomarkers in Military Veterans

High Risk of Insulin Resistance, PTSD Biomarkers in Military Veterans

Eighty-three veterans with PTSD participated in a study examining biological pathways between PTSD and metabolic diseases.

Cardiometabolic Event Risk Is Adversely Affected by Chronic Inflammation

Cardiometabolic Event Risk Is Adversely Affected by Chronic Inflammation

The least common condition, systemic lupus erythematosus, was associated with the highest association of experiencing multiple cardiometabolic events.

Elevated Adolescent BMI Increases Stroke Risk in Adulthood

Elevated Adolescent BMI Increases Stroke Risk in Adulthood

Over 37,000 men were tracked from ages 8 to 20 to examine the link between adolescent BMI and stroke risk.

Exercise Training Intervention Improves Ventricular Function in Adolescent T1D

Exercise Training Intervention Improves Ventricular Function in Adolescent T1D

Left ventricular function can be improved, but not normalized, in adolescents with type 1 diabetes.

Two-Hour Postload Glucose Test as Predictor of Cardiovascular Events

Two-Hour Postload Glucose Test as Predictor of Cardiovascular Events

Two-hour postload glucose better predicted cardiovascular events compared with fasting plasma glucose and HbA1c.

Metabolic Profile, Weight Increases Assessed in Ziprasidone Augmentation for Major Depressive Disorder

Metabolic Profile, Weight Increases Assessed in Ziprasidone Augmentation for Major Depressive Disorder

Escitalopram plus ziprasidone was found safe in certain patients, although the therapy required regular cardiovascular and metabolic monitoring.

Pediatric Respiratory and Atopic Outcomes With Free Sugar Consumption In Pregnancy

Pediatric Respiratory and Atopic Outcomes With Free Sugar Consumption In Pregnancy

Data from a UK cohort were used to examine the relationship between maternal sugar intake levels and pediatric respiratory and atopic outcomes.

Risk Factors for Preeclampsia and Pregnancy-Associated Stroke in Women

Risk Factors for Preeclampsia and Pregnancy-Associated Stroke in Women

Pregnancy-associated stroke risk is even higher in women with chronic hypertension, coagulopathies, and prothrombotic conditions.

Preventing Preterm Preeclampsia in At-Risk Women

Preventing Preterm Preeclampsia in At-Risk Women

Researchers examined the efficacy of aspirin in preventing preterm preeclampsia in women at risk.

Examining Health And Economic Burdens of Preeclampsia on Mothers, Children

Examining Health And Economic Burdens of Preeclampsia on Mothers, Children

Financial data for both mothers and children were examined through the first year of life.

Relationship Between Psoriasis and Cardiometabolic Comorbidities Examined

Relationship Between Psoriasis and Cardiometabolic Comorbidities Examined

Comorbidities included hyperlipidemia, hypertension, and type 2 diabetes, among others.

Major Adverse CV Event Prediction Via Coronary CT Angiography in T2D

Major Adverse CV Event Prediction Via Coronary CT Angiography in T2D

Extent and severity of coronary artery disease was examined in over 900 patients with type 2 diabetes.

Distinguishing Hypertension and Primary Aldosteronism Using Novel Immunoassay

Distinguishing Hypertension and Primary Aldosteronism Using Novel Immunoassay

Over 200 patients participated in the study of a novel immunoassay used to distinguish hypertension from hyperaldosteronism.

SGLT2 Inhibitors May Reduce Blood Pressure in Type 2 Diabetes

SGLT2 Inhibitors May Reduce Blood Pressure in Type 2 Diabetes

Sodium-glucose cotransporter 2 inhibitors reduced both systolic and diastolic blood pressure in patients with type 2 diabetes.

CV Event Risk Similar Regardless of Diabetes Diagnosis

CV Event Risk Similar Regardless of Diabetes Diagnosis

Statin and aspirin therapies in diabetes did not increased patients' risks of cardiovascular events.

FDA Approves Inclusion of LEADER Trial Data On Liraglutide Labeling

FDA Approves Inclusion of LEADER Trial Data On Liraglutide Labeling

Data from the 9300 patient LEADER trial is now eligible for inclusion on liraglutide injection packaging.

CV Risks in Juvenile Idiopathic Arthritis Tied to Serum Vitamin D Levels

CV Risks in Juvenile Idiopathic Arthritis Tied to Serum Vitamin D Levels

Patients with lower vitamin D levels had higher cIMT and were at elevated risk for cardiovascular conditions.

CVD Risk Management in Type 1 Diabetes Improved With Metformin

CVD Risk Management in Type 1 Diabetes Improved With Metformin

Although metformin did not improve glycemic control in patients with type 1 diabetes, the treatment did improve cardiovascular disease risk management.

USPSTF Updates Recommendations for Screening Obesity in Children and Adolescents

USPSTF Updates Recommendations for Screening Obesity in Children and Adolescents

Updates to the US Preventive Services Task Force's recommendations on obesity screening in children and adolescents focus on intensive behavioral interventions.

AHA Advisory: Replace Saturated Fat to Reduce CVD By 30%

AHA Advisory: Replace Saturated Fat to Reduce CVD By 30%

Widely promoted as healthy, coconut oil can increase LDL cholesterol levels similar to other saturated fats.

Type 2 Diabetes Death and CV Events Predicted by Systolic Blood Pressure Variability

Type 2 Diabetes Death and CV Events Predicted by Systolic Blood Pressure Variability

For patients with type 2 diabetes, visit-to-visit variability in systolic blood pressure may function as an independent predictor for cardiovascular events.

AHA: Promoting Self-Management in CVD Through Education

AHA: Promoting Self-Management in CVD Through Education

The most effective approaches to CVD self-management were tailored to individual patient needs and incorporated a multidisciplinary approach.

ADA: Clinical Benefit With Alirocumab in T2D Plus Statin Therapy

ADA: Clinical Benefit With Alirocumab in T2D Plus Statin Therapy

Researchers presented data from the ODYSSEY DM Insulin and Dyslipidemia trials at ADA 2017.

Cardiometabolic Disease Staging Score Useful in Quantifying T2D Risk in Overweight, Obesity

Cardiometabolic Disease Staging Score Useful in Quantifying T2D Risk in Overweight, Obesity

Cardiometabolic Disease Staging scores can be used to quantify diabetes risk and assess efficacy of weight loss pharmacotherapy in obesity.

Hypertension in Pregnancy: Are Antihypertensive Agents Safe?

Hypertension in Pregnancy: Are Antihypertensive Agents Safe?

According to Journal of the American Heart Association, pregnant women with chronic hypertension using antihypertensive agents reduces the risk of hypertension without added risk to the fetus.

FDA: Application Submitted for CV Safety Data Review of Insulin Degludec

FDA: Application Submitted for CV Safety Data Review of Insulin Degludec

The FDA is poised to review data from the DEVOTE trial, examining the rates of major adverse cardiovascular events in insulin degludec vs insulin glargine.

Metabolic Syndrome and Parkinson's Progression: Is There A Link?

Metabolic Syndrome and Parkinson's Progression: Is There A Link?

Patients with metabolic syndrome experienced an increase in Unified Parkinson's Disease Rating Scale (UPDRS) scores.

Maternal Overweight, Obesity Linked to Increase in Fetal Birth Defects

Maternal Overweight, Obesity Linked to Increase in Fetal Birth Defects

Researchers suggest that women with overweight or obesity aim to lose weight before becoming pregnant.

Serum Cholesterol Levels Over Time and Risk of Parkinson's Disease

Serum Cholesterol Levels Over Time and Risk of Parkinson's Disease

The role of cholesterol in Parkinson's disease is not well understood.

Extended-Release Naltrexone/Bupropion Efficacious for Weight Loss in Type 2 Diabetes

Extended-Release Naltrexone/Bupropion Efficacious for Weight Loss in Type 2 Diabetes

Two studies examined the effects of naltrexone/bupropion on weight loss, glycemic parameters, and cardiovascular risks in patients with type 2 diabetes.

Glycemic Control and Mortality Risk With Statins in Type 2 Diabetes

Glycemic Control and Mortality Risk With Statins in Type 2 Diabetes

Patients with type 2 diabetes taking statins after insulin initiation had better glycemic control, but their risk for mortality was higher compared with patients who did not take statins.

Orthostatic Hypotension In Type 2 Diabetes Increases CV, Cerebrovascular Events

Orthostatic Hypotension In Type 2 Diabetes Increases CV, Cerebrovascular Events

Riser patterns in patients' BP resulting from orthostatic hypotension has been linked to increased rates of mortality and major adverse cardiac and cerebrovascular events.

Low-Carbohydrate vs Low-fat Diet Success In Patients With Prediabetes Differs According to Fasting Insulin Levels

Low-Carbohydrate vs Low-fat Diet Success In Patients With Prediabetes Differs According to Fasting Insulin Levels

Fasting plasma glucose, insulin, and insulin sensitivity levels were measured to determine their prognostic value as markers for long-term weight loss.

SPRINT Subanalysis: Intensive SBP Control in Prediabetes vs Normal Fasting Blood Glucose

SPRINT Subanalysis: Intensive SBP Control in Prediabetes vs Normal Fasting Blood Glucose

Researchers conducted a subgroup analysis of the SPRINT clinical trial to determine whether intensive blood pressure treatment outcomes were similar in patients with prediabetes vs normal fasting blood glucose levels.

Canagliflozin Reduces Cardiovascular Stress in Older Patients With T2D

Canagliflozin Reduces Cardiovascular Stress in Older Patients With T2D

Canagliflozin reduced levels of cardiovascular stress biomarkers N-terminal pro-B type natriuretic peptide and high sensitivity troponin I.

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