Cardiovascular & Metabolic Disorders

Hypertensive Disorders During Pregnancy Increase Risk for Future CVD

Hypertensive Disorders During Pregnancy Increase Risk for Future CVD

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Women with hypertensive disorders during pregnancy have a significantly greater risk for future cardiovascular disease when compared with normotensive expecting mothers.

Case Study: Man With Obesity, Hypertension Presenting With Worsening Palpitations

Case Study: Man With Obesity, Hypertension Presenting With Worsening Palpitations

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A man presents to the emergency department having had palpitations for the past week, and he has a medical history of hypertension, obesity, and hyperlipidemia. What's the diagnosis?

CVD Hospitalization Rates in Diabetes Decreased in 1998-2014

CVD Hospitalization Rates in Diabetes Decreased in 1998-2014

Cardiovascular disease hospitalization rates have declined in recent years among individuals with and those without diabetes.

Higher Childhood BMI Associated With Adult Ischemic Stroke

Higher Childhood BMI Associated With Adult Ischemic Stroke

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Higher childhood body mass index and increases in BMI during childhood are linked to an increased risk of early adult ischemic stroke.

Insulin-Induced Weight Gain Not Associated With Adverse CV Outcomes in T2D

Insulin-Induced Weight Gain Not Associated With Adverse CV Outcomes in T2D

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Despite the well‐recognized correlation between weight gain and cardiovascular (CV) disease, there is little direct evidence relating to the impact of insulin‐induced weight gain on CV outcomes.

No Difference in Cardiovascular Outcomes With Exenatide vs Placebo in T2D

No Difference in Cardiovascular Outcomes With Exenatide vs Placebo in T2D

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Once-weekly administration of extended-release exenatide in patients with T2D at a wide range of cardiovascular risk appeared not to cause an increase in their overall cardiovascular risk.

Empagliflozin Reduces CVD Risk in Patients With T2D and PAD

Empagliflozin Reduces CVD Risk in Patients With T2D and PAD

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Empagliflozin lowered the risk of cardiovascular death vs placebo when added to standard of care in adults with both type 2 diabetes and peripheral artery disease.

High-Sensitivity CRP and LDL-C Predictive of Subsequent MACE in T2D

High-Sensitivity CRP and LDL-C Predictive of Subsequent MACE in T2D

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Levels of high sensitivity C-reactive protein may help risk stratify those patients with T2D and recent acute coronary syndrome at further risk of recurrent cardiovascular events.

Statin Use for CVD Prevention Increases Diabetes Risk in Overweight Patients

Statin Use for CVD Prevention Increases Diabetes Risk in Overweight Patients

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The association between statin use and diabetes risk in a cohort of overweight and obese patients was examined.

High Grip Strength Associated With Lower Risk for Diabetes-Related AEs

High Grip Strength Associated With Lower Risk for Diabetes-Related AEs

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Grip strength has clinical utility in identifying people with diabetes at risk for poor health outcomes.

FDA Approves Drug for Mucopolysaccharidosis Type VII

FDA Approves Drug for Mucopolysaccharidosis Type VII

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Mepsevii replaces beta-glucuronidase, the deficiency of which causes an abnormal buildup of toxic materials in the body's cells.

Improving Vascular Function in Pediatric T1D With Metformin

Improving Vascular Function in Pediatric T1D With Metformin

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Study aimed to determine the effect of metformin on vascular health in children with T1D and above average weight.

Postpartum Hypertension in Preeclampsia: Do Puerperal NSAIDs Effect Risk?

Postpartum Hypertension in Preeclampsia: Do Puerperal NSAIDs Effect Risk?

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Investigators encourage further research on the use of NSAIDs in women with preeclampsia who develop postpartum hypertension.

Acarbose Reduces Diabetes Risk in Coronary Heart Disease

Acarbose Reduces Diabetes Risk in Coronary Heart Disease

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Acarbose, an α-glucosidase inhibitor, decreased the incidence of diabetes in a population with impaired glucose tolerance who were at low risk of cardiovascular events.

Improving NSTEMI Outcomes in T2D With NOCS: Efficacy of Incretin

Improving NSTEMI Outcomes in T2D With NOCS: Efficacy of Incretin

People with type 2 diabetes and NOCS-NSTEMI who used incretin had a better prognosis than non-incretin users.

Severe Hypoglycemia Associated With Increased Mortality Risk in T2D

Severe Hypoglycemia Associated With Increased Mortality Risk in T2D

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A study confirms whether severe hypoglycemia increases risk for all-cause mortality in patients with type 2 diabetes.

Glucose Patterns and the Future Development of Diabetes

Glucose Patterns and the Future Development of Diabetes

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Study revealed heterogeneity in plasma glucose response to oral glucose intake beyond the established glucose criteria based on fasting plasma glucose and 2 h post-load plasma glucose levels.

Gestational Diabetes Associated With Adiposity, Puberty Onset in Offspring

Gestational Diabetes Associated With Adiposity, Puberty Onset in Offspring

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Researchers assessed the impact of maternal gestational diabetes on insulin resistance and adiposity in adolescent offspring.

Type 2 Diabetes Protective Against Aortic Aneurysm, Dissection

Type 2 Diabetes Protective Against Aortic Aneurysm, Dissection

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Studies have not previously examined long-term risks or mortality after aortic aneurysm or dissection in people with type 2 diabetes.

Ventricular Function With Vildagliptin in T2D and CHF

Ventricular Function With Vildagliptin in T2D and CHF

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Study highlights the need to examine the safety of new glucose-lowering treatments specifically in patients with diabetes and heart failure and reduced ejection fraction.

Expert Roundtable: AHA Update on Dietary Fat Intake and CVD Risk

Expert Roundtable: AHA Update on Dietary Fat Intake and CVD Risk

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The AHA now recommends replacing both saturated and trans fats with unsaturated fats from vegetable oils, nuts, seeds, and oily fish.

HbA1c Predictive of Poor Heart Failure Outcomes in T2D

HbA1c Predictive of Poor Heart Failure Outcomes in T2D

Based on glycemic control and treatment method, type 2 diabetes in the heart failure population can be indicative of various risk associations.

Sudden Death in T2D: Examining the Most Common Cause of CV Mortality

Sudden Death in T2D: Examining the Most Common Cause of CV Mortality

Heart failure prevention may be an opportunity to reduce the risk of death in specific cardiovascular subcategories.

High-Dose Beta-Blockers More Effective in Chronic Heart Failure, Diabetes

High-Dose Beta-Blockers More Effective in Chronic Heart Failure, Diabetes

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Greater prognostic advantages were associated with high-dose beta blockers in chronic heart failure with diabetes.

ADA Position Statement Update: Hypertension Management in Diabetes

ADA Position Statement Update: Hypertension Management in Diabetes

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The latest ADA hypertension position statement incorporates advances in care since 2003.

Evolocumab May Decrease Cardiovascular Risk in Patients With and Without Diabetes

Evolocumab May Decrease Cardiovascular Risk in Patients With and Without Diabetes

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PCSK9 inhibition with evolocumab might be an attractive therapy in patients with diabetes, and no discernible effect on glycaemia.

SPRINT Update: Positive CVD Outcomes With Intensive Blood Pressure Management in Prediabetes

SPRINT Update: Positive CVD Outcomes With Intensive Blood Pressure Management in Prediabetes

Patients with prediabetes who experienced intensive blood pressure management had better outcomes with CVD events and all-cause mortality.

Examining Inclusion of T2D Medication Adherence Data in Studies

Examining Inclusion of T2D Medication Adherence Data in Studies

Results suggest that medication adherence is associated with reduced risk of all-cause mortality in T2D.

Predicting Adult MetS, T2D, CV Risks in Childhood

Predicting Adult MetS, T2D, CV Risks in Childhood

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BMI measurement alone can also be used to determine associations between childhood and adulthood conditions.

ICU Resource Use After Cardiac Surgery Increased With Obesity

ICU Resource Use After Cardiac Surgery Increased With Obesity

Increasing obesity is associated with increased ICU resource utilization in patients undergoing cardiac surgery.

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