Cardiovascular & Metabolic Disorders

High Albumin-to-Creatinine Ratio Associated With Increased Risk for Microalbuminuria and Future CVD in Adolescents

High Albumin-to-Creatinine Ratio Associated With Increased Risk for Microalbuminuria and Future CVD in Adolescents

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The association between albumin-to-creatinine ratio and risk for diabetic nephropathy and CVD was examined over 2 to 4 years.

CDC: More People With High Cholesterol Taking Medications

CDC: More People With High Cholesterol Taking Medications

There has been a substantial increase in the percentage of patients with high cholesterol over age 60 years taking lipid-lowering medications from 2005 to 2016, but such increases have not been seen among younger patients with high cholesterol.

Second-Line Sulfonylurea Therapy Linked to Cardiovascular Events in Type 2 Diabetes

Second-Line Sulfonylurea Therapy Linked to Cardiovascular Events in Type 2 Diabetes

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Researchers assessed whether adding or switching to sulfonylureas is linked to increased risk for myocardial infarction, ischemic stroke, hypoglycemia, and all-cause mortality.

CVD Risk Independently Predicted by Poor Lifestyle Factors

CVD Risk Independently Predicted by Poor Lifestyle Factors

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High BMI, low physical activity levels, and frequent smoking and high genetic risk increased the risk for atrial fibrillation, coronary artery disease, hypertension, stroke, and diabetes.

Statin Use and Cardiovascular Risk Perception Varies Among Races

Statin Use and Cardiovascular Risk Perception Varies Among Races

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African American patients were less likely than white patients to be treated with any statin and at the guideline-recommended intensity.

Cardiovascular Disease Risk Lower in Women With Type 2 Diabetes

Cardiovascular Disease Risk Lower in Women With Type 2 Diabetes

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Investigators examined gender differences in baseline characteristics and outcomes in patients with t2d and ASCVD.

Improving Sleep Quality May Reduce Cardiovascular Risk in Bipolar Disorder

Improving Sleep Quality May Reduce Cardiovascular Risk in Bipolar Disorder

The relationship between circadian rhythm and sleep measures and components of metabolic syndrome in patients with bipolar disorder.

Depression May Be Associated With Metabolic Syndrome in Older Adults

Depression May Be Associated With Metabolic Syndrome in Older Adults

Older adults with metabolic syndrome experienced higher rates of depressive symptoms compared with older adults without metabolic syndrome.

Revised Pooled Cohort Equations for CVD Risk Improve Accuracy of Estimates

Revised Pooled Cohort Equations for CVD Risk Improve Accuracy of Estimates

Investigators revised pooled cohort equations to improve clinical accuracy to predict risk for cardiovascular disease.

Cardiovascular Outcomes in Patients With ACS, Diabetes Using Alirocumab

Cardiovascular Outcomes in Patients With ACS, Diabetes Using Alirocumab

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Investigators examine the effects of the PCSK9 inhibitor alirocumab in patients with recent acute coronary syndrome and diabetes.

Elevated Triglycerides, Diabetes May Be Predictors of Major Cardiovascular Events

Elevated Triglycerides, Diabetes May Be Predictors of Major Cardiovascular Events

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Investigators examined cardiovascular outcomes in patients with elevated triglyceridemia and diabetes treated with statins.

Good Sleep Tied to Better Cardiometabolic Health in Youths

Good Sleep Tied to Better Cardiometabolic Health in Youths

These results support the need to assess the role of sleep quantity and quality interventions as strategies for improving cardiovascular risk profiles of adolescents.

Sex Hormone Levels May Affect Postmenopausal Heart Disease Risk

Sex Hormone Levels May Affect Postmenopausal Heart Disease Risk

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Researchers assessed the effect of testosterone, estradiol, dehydroepiandrosterone, and sex hormone-binding globulin levels on coronary heart disease, heart failure, and cardiovascular disease in postmenopausal women.

Fenofibrate Improves Cholesterol Levels in Type 2 Diabetes

Fenofibrate Improves Cholesterol Levels in Type 2 Diabetes

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To understand the mechanism underlying the benefit of fenofibrate on vascular complications in patients with type 2 diabetes, investigators assessed carotid intima thickness as a marker of subclinical atherosclerosis.

Metabolic Health Maintenance Key to Preventing Cardiovascular Disease

Metabolic Health Maintenance Key to Preventing Cardiovascular Disease

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Regardless of long-term metabolic health maintenance, obesity remains a risk factor for cardiovascular disease.

Thyroid Cancer Survivors at Higher Risk for Cardiovascular Disease

Thyroid Cancer Survivors at Higher Risk for Cardiovascular Disease

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Investigators sought to assess the link between treatment for thyroid cancer and subsequent cardiac and vascular complications.

Depression, C-Reactive Protein, and Osteoprotegerin May Affect Dyslipidemia

Depression, C-Reactive Protein, and Osteoprotegerin May Affect Dyslipidemia

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Investigators sought to determine whether serum lipid levels were associated with depression in patients with psychotic disorders.

Injectable Progestin-Only Contraceptives May Increase Risk for VTE

Injectable Progestin-Only Contraceptives May Increase Risk for VTE

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Investigators examined the effect of progestin-only contraceptive on cardiometabolic outcomes, including stroke, MI, hypertension, diabetes, and VTE.

Improved calculations suggest major changes to statin, aspirin, and blood pressure medication prescribing

Updated risk calculations suggest that fewer people should be classified within the high-risk category for CVD.

Fewer Major Adverse Cardiovascular Events With New Antihyperglycemic Drugs With Lower Hypoglycemic Risk

Fewer Major Adverse Cardiovascular Events With New Antihyperglycemic Drugs With Lower Hypoglycemic Risk

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Investigators proposed that reduction in MACE may be proportional to the magnitude of HbA1c reduction seen with newer antihyperglycemic agents.

Intensive LDL-C lowering reduces mortality in patients with higher baseline LDL-C

In this systematic review and meta-analysis, more intensive compared with less itensive LDL-C lowering was associated with a greater reduction in risk of total and cardiovascular mortality in trials of patients with higher baseline LDL-C levels.

Increased Risk for Mortality in People With Diabetes, CHD Taking Beta-Blockers

Increased Risk for Mortality in People With Diabetes, CHD Taking Beta-Blockers

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Further studies are needed to assess whether beta-blockers are effective in reducing mortality and coronary events in patients with diabetes receiving optimal medical treatment.

Risk Factors for Cardiovascular Disease in Youth With Type 1 Diabetes

Risk Factors for Cardiovascular Disease in Youth With Type 1 Diabetes

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Early treatment of cardiovascular disease risk factors such as dyslipidemia and hypertension will have long-term benefits with low risk and cost and should be more widely used in pediatric type 1 diabetes care.

Influence of Gender on Cardiovascular Risk and Glycemic Control in T1D

Influence of Gender on Cardiovascular Risk and Glycemic Control in T1D

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Researchers assessed differences in glycemic control, major cardiovascular risk factors, diabetes-related complications, sexual dysfunction prevalence, and endothelial function in young men and women with type 1 diabetes.

Obesity May Increase Cardiovascular Morbidity, Mortality

Obesity May Increase Cardiovascular Morbidity, Mortality

Results provide critical perspective on cardiovascular disease associated with overweight and obesity and challenge both the obesity paradox as well as the view that overweight is associated with greater longevity.

Proliferative Diabetic Retinopathy Independently Associated With CVD in T1D

Proliferative Diabetic Retinopathy Independently Associated With CVD in T1D

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Study found that the absence of proliferative diabetic retinopathy in those with stage 3b chronic kidney disease is associated with a lower prevalence of cardiovascular disease in patients with long duration of type 1 diabetes.

Prevalence, Effect of Undetected Diabetes in Percutaneous Coronary Intervention

Prevalence, Effect of Undetected Diabetes in Percutaneous Coronary Intervention

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Abnormal glucose metabolism was detected in 1 out of 3 patients with nondiabetic percutaneous coronary intervention and was independently associated with a significantly higher event risk.

Sulfonylureas and Risk of Sudden Cardiac Arrest, Ventricular Arrhythmia Examined

Sulfonylureas and Risk of Sudden Cardiac Arrest, Ventricular Arrhythmia Examined

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Study examined the association between individual antidiabetic sulfonylureas and outpatient-originating sudden cardiac arrest and ventricular arrhythmia.

Increased Adiposity Raises Myocardial Infarction Risk More in Women

Increased Adiposity Raises Myocardial Infarction Risk More in Women

Increases in waist circumference and waist-to-hip ratio are associated with a greater excess risk of myocardial infarction in women than men.

Effect of Fenofibrate Varies Widely in Type 2 Diabetes

Effect of Fenofibrate Varies Widely in Type 2 Diabetes

The method of individualized treatment effect prediction of fenofibrate on major cardiovascular events risk reduction in T2D can be used to guide clinical decision-making.

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