Cardiovascular & Metabolic Disorders

USPSTF Updates Recommendations for Screening Obesity in Children and Adolescents

USPSTF Updates Recommendations for Screening Obesity in Children and Adolescents

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Updates to the US Preventive Services Task Force's recommendations on obesity screening in children and adolescents focus on intensive behavioral interventions.

AHA Advisory: Replace Saturated Fat to Reduce CVD By 30%

AHA Advisory: Replace Saturated Fat to Reduce CVD By 30%

Widely promoted as healthy, coconut oil can increase LDL cholesterol levels similar to other saturated fats.

Type 2 Diabetes Death and CV Events Predicted by Systolic Blood Pressure Variability

Type 2 Diabetes Death and CV Events Predicted by Systolic Blood Pressure Variability

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For patients with type 2 diabetes, visit-to-visit variability in systolic blood pressure may function as an independent predictor for cardiovascular events.

AHA: Promoting Self-Management in CVD Through Education

AHA: Promoting Self-Management in CVD Through Education

The most effective approaches to CVD self-management were tailored to individual patient needs and incorporated a multidisciplinary approach.

ADA: Clinical Benefit With Alirocumab in T2D Plus Statin Therapy

ADA: Clinical Benefit With Alirocumab in T2D Plus Statin Therapy

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Researchers presented data from the ODYSSEY DM Insulin and Dyslipidemia trials at ADA 2017.

Maternal Deaths in the United States: Sounding a Call to Action

Maternal Deaths in the United States: Sounding a Call to Action

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Despite multiple measures and goals to reduce US maternal mortality rates, the latest data suggest the United States is far behind the rest of the world in maternal health care.

Hypertension in Pregnancy: Are Antihypertensive Agents Safe?

Hypertension in Pregnancy: Are Antihypertensive Agents Safe?

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According to Journal of the American Heart Association, pregnant women with chronic hypertension using antihypertensive agents reduces the risk of hypertension without added risk to the fetus.

Metabolic Syndrome and Parkinson's Progression: Is There A Link?

Metabolic Syndrome and Parkinson's Progression: Is There A Link?

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Patients with metabolic syndrome experienced an increase in Unified Parkinson's Disease Rating Scale (UPDRS) scores.

Serum Cholesterol Levels Over Time and Risk of Parkinson's Disease

Serum Cholesterol Levels Over Time and Risk of Parkinson's Disease

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The role of cholesterol in Parkinson's disease is not well understood.

Extended-Release Naltrexone/Bupropion Efficacious for Weight Loss in Type 2 Diabetes

Extended-Release Naltrexone/Bupropion Efficacious for Weight Loss in Type 2 Diabetes

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Two studies examined the effects of naltrexone/bupropion on weight loss, glycemic parameters, and cardiovascular risks in patients with type 2 diabetes.

Glycemic Control and Mortality Risk With Statins in Type 2 Diabetes

Glycemic Control and Mortality Risk With Statins in Type 2 Diabetes

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Patients with type 2 diabetes taking statins after insulin initiation had better glycemic control, but their risk for mortality was higher compared with patients who did not take statins.

Orthostatic Hypotension In Type 2 Diabetes Increases CV, Cerebrovascular Events

Orthostatic Hypotension In Type 2 Diabetes Increases CV, Cerebrovascular Events

Riser patterns in patients' BP resulting from orthostatic hypotension has been linked to increased rates of mortality and major adverse cardiac and cerebrovascular events.

Low-Carbohydrate vs Low-fat Diet Success In Patients With Prediabetes Differs According to Fasting Insulin Levels

Low-Carbohydrate vs Low-fat Diet Success In Patients With Prediabetes Differs According to Fasting Insulin Levels

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Fasting plasma glucose, insulin, and insulin sensitivity levels were measured to determine their prognostic value as markers for long-term weight loss.

SPRINT Subanalysis: Intensive SBP Control in Prediabetes vs Normal Fasting Blood Glucose

SPRINT Subanalysis: Intensive SBP Control in Prediabetes vs Normal Fasting Blood Glucose

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Researchers conducted a subgroup analysis of the SPRINT clinical trial to determine whether intensive blood pressure treatment outcomes were similar in patients with prediabetes vs normal fasting blood glucose levels.

Canagliflozin Reduces Cardiovascular Stress In Older Patients With Type 2 Diabetes

Canagliflozin Reduces Cardiovascular Stress In Older Patients With Type 2 Diabetes

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Canagliflozin reduced levels of cardiovascular stress biomarkers N-terminal pro-B type natriuretic peptide and high sensitivity troponin I.

Dapagliflozin Improves Endothelial Function in Type 2 Diabetes

Dapagliflozin Improves Endothelial Function in Type 2 Diabetes

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Flow mediated dilation changes improved in patients who received dapagliflozin.

Glucose Tolerance, Triglyceride Levels in Prediabetes Improve With Sitagliptin

Glucose Tolerance, Triglyceride Levels in Prediabetes Improve With Sitagliptin

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Sitagliptin improved glucose excursion and lowered triglyceride levels in men with prediabetes who were also overweight.

GLP-1 Analog Counteracts Antipsychotic-Induced Glucose Intolerance, Weight Gain

GLP-1 Analog Counteracts Antipsychotic-Induced Glucose Intolerance, Weight Gain

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Interventions seeking to counteract antipsychotic-induced weight gain and cardiometabolic disturbances have had limited success.

Diet and Exercise Reduce Gestational Weight Gain, Not Neonatal Adiposity

Diet and Exercise Reduce Gestational Weight Gain, Not Neonatal Adiposity

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Neonates did not differ in terms of birthweight, fat mass, body fat percentage, and sum of skinfolds, regardless of treatment.

Chronic Kidney Disease vs Type 2 Diabetes Mortality Risk in CVD

Chronic Kidney Disease vs Type 2 Diabetes Mortality Risk in CVD

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Patients with cardiovascular disease and both type 2 diabetes and chronic kidney disease had the highest risk for mortality.

Reducing Arteriosclerosis in T2D With Antioxidant Resveratrol

Reducing Arteriosclerosis in T2D With Antioxidant Resveratrol

Resveratrol supplements were fount to activate the SIRT1 gene, which delays aging and the development of various diseases.

Reduced Cardiovascular Events in Type 2 Diabetes Treated With Dapagliflozin

Reduced Cardiovascular Events in Type 2 Diabetes Treated With Dapagliflozin

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Patients with type 2 diabetes had lower rates of heart failure hospitalization, MACE, and all-cause mortality when treated with dapagliflozin.

Risks Associated With Anticoagulant Use in Pregnancy

Risks Associated With Anticoagulant Use in Pregnancy

Vitamin K antagonists and low-molecular weight heparin were associated with the lowest risks of adverse maternal and fetal outcomes.

Low Body Mass Index and Alzheimer Disease: Is There a Link?

Low Body Mass Index and Alzheimer Disease: Is There a Link?

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Individuals with low BMI are not at an increased risk for Alzheimer disease.

Long-Term Anabolic-Androgenic Steroid Use Linked to Myocardial Dysfunction and Atherosclerosis

Long-Term Anabolic-Androgenic Steroid Use Linked to Myocardial Dysfunction and Atherosclerosis

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Long-term use of anabolic-androgenic steroids increases risks for decreased left ventricular diastolic function and increased coronary plaque volume.

USPSTF: Updated Preeclampsia Screening Recommendations

USPSTF: Updated Preeclampsia Screening Recommendations

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Women at high risk for preeclampsia should take low-dose aspirin as a preventive therapy.

Frequent Hot Flashes Worsened Endothelial Function in Younger Midlife Women

Frequent Hot Flashes Worsened Endothelial Function in Younger Midlife Women

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Age significantly affected the association between hot flash status and flow-mediated dilation, particularly in younger women.

Fewer Menstrual Cycles May Lead to Increased Risk for Heart Failure

Fewer Menstrual Cycles May Lead to Increased Risk for Heart Failure

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The fewer menstrual cycles women had over a lifetime placed them at greater risk for incident heart failure.

Case Report: Insulin Autoimmune Syndrome Following Rituximab Therapy

Case Report: Insulin Autoimmune Syndrome Following Rituximab Therapy

A 37-year-old woman presented to the emergency department with recurrent dizziness following her recent pregnancy.

Cardiometabolic Comorbidities, Hospitalizations, and Costs Associated With Schizophrenia and Bipolar Disorder

Cardiometabolic Comorbidities, Hospitalizations, and Costs Associated With Schizophrenia and Bipolar Disorder

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People with schizophrenia or bipolar disorder experience twice the rate of diabetes and metabolic syndrome compared to the general population.

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