Cardiovascular & Metabolic Disorders

Case: A 67-Year-Old Man With Shortness of Breath After Wildfires

Case: A 67-Year-Old Man With Shortness of Breath After Wildfires

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A patient living near an area experiencing frequent wildfires is concerned about the potential negative effect that the wildfires may have on his health.

T2D May Play a Protective Role Against Developing Aortic Diseases

T2D May Play a Protective Role Against Developing Aortic Diseases

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The novel findings in this study suggest that patients with type 2 diabetes have a significantly reduced risk for short-term mortality after hospitalization for aortic aneurysm compared with population-based control subjects.

Reducing CV Risk in Patients With Rheumatoid Arthritis and Diabetes

Reducing CV Risk in Patients With Rheumatoid Arthritis and Diabetes

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Abatacept conferred a greater reduction in cardiovascular risk compared with tumor necrosis factor inhibitors in patients with rheumatoid arthritis and diabetes.

Little Effect on Metabolic Risk Factors With Addition of SSRIs to Antipsychotics

Little Effect on Metabolic Risk Factors With Addition of SSRIs to Antipsychotics

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A combination of selective serotonin reuptake inhibitors and antipsychotics does not lead to further deterioration of metabolic variables; however, metabolic monitoring should be performed.

Updated <I>Standards of Medical Care in Diabetes</I> Focuses on Cardiovascular Disease

Updated Standards of Medical Care in Diabetes Focuses on Cardiovascular Disease

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ADA's recommendations reflect the latest advances in evidence-based research to improve care for millions of people with diabetes.

Duration of Prediabetes, Diabetes Independently Associated With Subclinical Atherosclerosis, Cardiac Dysfunction

Duration of Prediabetes, Diabetes Independently Associated With Subclinical Atherosclerosis, Cardiac Dysfunction

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Data emphasize the importance of early identification and management of those at risk for diabetes and prediabetes in order to limit exposure to the adverse cardiovascular effects of a longer duration of these conditions.

Lower Bone Mineral Density May Increase Intracranial Aneurysm Risk

Lower Bone Mineral Density May Increase Intracranial Aneurysm Risk

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A lower bone mineral density in the lumbar spine, femoral neck, and hip is associated with an increased risk for intracranial aneurysm.

Gestational Diabetes May Increase Risk for Hypertension, Ischemic Heart Disease, T2D

Gestational Diabetes May Increase Risk for Hypertension, Ischemic Heart Disease, T2D

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Clinical guidelines should include postpartum screening and management for all cardiovascular risk factors in women diagnosed with gestational diabetes and not restrict it to diabetes.

Does Bariatric Surgery Reduce CVD Risk Factors in Adolescents?

Does Bariatric Surgery Reduce CVD Risk Factors in Adolescents?

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Weight loss after bariatric surgery in adolescents predicts the degree of longitudinal improvement in elevated high-sensitivity C-reactive protein, hyperinsulinemia, dyslipidemia, and diabetes.

New Recommendations for High Blood Pressure Management, Prevention

New Recommendations for High Blood Pressure Management, Prevention

New recommendations have been developed for the prevention, detection, evaluation, and management of high blood pressure.

Adding Ezetimibe to Statin Therapy: Cardiovascular Outcomes in Diabetes

Adding Ezetimibe to Statin Therapy: Cardiovascular Outcomes in Diabetes

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In patients with an acute coronary syndrome and LDL-C >50 mg/dL, healthcare providers should consider adding ezetimibe to statin therapy to reduce the risk of cardiovascular events.

Plasma Volume Changes Mediate Risk of CV Mortality With Empagliflozin

Plasma Volume Changes Mediate Risk of CV Mortality With Empagliflozin

The reduction in risk of cardiovascular death with empagliflozin is most mediated by changes in hematocrit and hemoglobin.

Higher Risk for Stroke, MI in Patients With Gout, Diabetes

Higher Risk for Stroke, MI in Patients With Gout, Diabetes

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Patients with both gout and diabetes are at a much higher risk for stroke and myocardial infarction than with diabetes alone.

Intensive Blood Pressure Lowering Reduces CV Events Similarly in Patients With/Without T2D

Intensive Blood Pressure Lowering Reduces CV Events Similarly in Patients With/Without T2D

Researchers assessed the effect of both type 2 diabetes and baseline cardiovascular disease risk on the treatment effect of intensive blood pressure lowering based on data and pooled analysis from 14,094 patients.

CV Event Prediction, Risk Assessment in Type 2 Diabetes

CV Event Prediction, Risk Assessment in Type 2 Diabetes

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Risk of cardiovascular events in people with type 2 diabetes and subgroups of coronary artery disease was examined.

Subclinical Primary Aldosteronism Increases Hypertension Risk in Normotensive Patients

Subclinical Primary Aldosteronism Increases Hypertension Risk in Normotensive Patients

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Future studies using a renin phenotype-driven approach may efficiently identify new-onset or mild hypertension.

Urinary Albumin-to-Creatinine Ratio Aids CV Risk Assessment in T2D

Urinary Albumin-to-Creatinine Ratio Aids CV Risk Assessment in T2D

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Urinary albumin-to-creatinine ratio can be independently associated with various adverse CV outcomes.

Coronary Artery Bypass Grafting: Preferred Method of Revascularization in Diabetes

Coronary Artery Bypass Grafting: Preferred Method of Revascularization in Diabetes

In patients with diabetes, coronary artery bypass grafting may be the preferred method of revascularization, with lower rates of major adverse cardiac or cerebrovascular events.

Physical Activity, Sedentary Time May Increase Cardiometabolic Risk Markers in Prediabetes

Physical Activity, Sedentary Time May Increase Cardiometabolic Risk Markers in Prediabetes

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A study sought to clarify whether total physical activity during the day is equally as important as achieving high levels of intensity associated with moderate-to-vigorous physical activity.

More Evidence That Saxagliptin Does Not Increase Risk for AMI in Diabetes

More Evidence That Saxagliptin Does Not Increase Risk for AMI in Diabetes

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Patients with diabetes taking saxagliptin, sitagliptin, second-generation sulfonylureas, pioglitazone, and long-acting insulin were assessed for the risk of acute myocardial infarction.

Elderly Patients With T2D, Heart Failure Have High Risk for Mortality

Elderly Patients With T2D, Heart Failure Have High Risk for Mortality

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A strong association was found in study between poor survival in elderly patients with type 2 diabetes and cardiovascular complications, especially heart failure.

Fertility Hormone Therapy and Cardiovascular Outcomes: What We Know

Fertility Hormone Therapy and Cardiovascular Outcomes: What We Know

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Although the use of fertility therapy has steadily increased in the past few decades, research findings pertaining to related long-term cardiovascular outcomes are scarce and conflicting.

Hypertensive Disorders During Pregnancy Increase Risk for Future CVD

Hypertensive Disorders During Pregnancy Increase Risk for Future CVD

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Women with hypertensive disorders during pregnancy have a significantly greater risk for future cardiovascular disease when compared with normotensive expecting mothers.

Case Study: Man With Obesity, Hypertension Presenting With Worsening Palpitations

Case Study: Man With Obesity, Hypertension Presenting With Worsening Palpitations

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A man presents to the emergency department having had palpitations for the past week, and he has a medical history of hypertension, obesity, and hyperlipidemia. What's the diagnosis?

CVD Hospitalization Rates in Diabetes Decreased in 1998-2014

CVD Hospitalization Rates in Diabetes Decreased in 1998-2014

Cardiovascular disease hospitalization rates have declined in recent years among individuals with and those without diabetes.

Higher Childhood BMI Associated With Adult Ischemic Stroke

Higher Childhood BMI Associated With Adult Ischemic Stroke

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Higher childhood body mass index and increases in BMI during childhood are linked to an increased risk of early adult ischemic stroke.

Insulin-Induced Weight Gain Not Associated With Adverse CV Outcomes in T2D

Insulin-Induced Weight Gain Not Associated With Adverse CV Outcomes in T2D

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Despite the well‐recognized correlation between weight gain and cardiovascular (CV) disease, there is little direct evidence relating to the impact of insulin‐induced weight gain on CV outcomes.

No Difference in Cardiovascular Outcomes With Exenatide vs Placebo in T2D

No Difference in Cardiovascular Outcomes With Exenatide vs Placebo in T2D

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Once-weekly administration of extended-release exenatide in patients with T2D at a wide range of cardiovascular risk appeared not to cause an increase in their overall cardiovascular risk.

Empagliflozin Reduces CVD Risk in Patients With T2D and PAD

Empagliflozin Reduces CVD Risk in Patients With T2D and PAD

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Empagliflozin lowered the risk of cardiovascular death vs placebo when added to standard of care in adults with both type 2 diabetes and peripheral artery disease.

High-Sensitivity CRP and LDL-C Predictive of Subsequent MACE in T2D

High-Sensitivity CRP and LDL-C Predictive of Subsequent MACE in T2D

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Levels of high sensitivity C-reactive protein may help risk stratify those patients with T2D and recent acute coronary syndrome at further risk of recurrent cardiovascular events.

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