Cardiovascular & Metabolic Disorders

Increased Risk for Mortality in People With Diabetes, CHD Taking Beta-Blockers

Increased Risk for Mortality in People With Diabetes, CHD Taking Beta-Blockers

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Further studies are needed to assess whether beta-blockers are effective in reducing mortality and coronary events in patients with diabetes receiving optimal medical treatment.

Risk Factors for Cardiovascular Disease in Youth With Type 1 Diabetes

Risk Factors for Cardiovascular Disease in Youth With Type 1 Diabetes

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Early treatment of cardiovascular disease risk factors such as dyslipidemia and hypertension will have long-term benefits with low risk and cost and should be more widely used in pediatric type 1 diabetes care.

Influence of Gender on Cardiovascular Risk and Glycemic Control in T1D

Influence of Gender on Cardiovascular Risk and Glycemic Control in T1D

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Researchers assessed differences in glycemic control, major cardiovascular risk factors, diabetes-related complications, sexual dysfunction prevalence, and endothelial function in young men and women with type 1 diabetes.

Obesity May Increase Cardiovascular Morbidity, Mortality

Obesity May Increase Cardiovascular Morbidity, Mortality

Results provide critical perspective on cardiovascular disease associated with overweight and obesity and challenge both the obesity paradox as well as the view that overweight is associated with greater longevity.

Proliferative Diabetic Retinopathy Independently Associated With CVD in T1D

Proliferative Diabetic Retinopathy Independently Associated With CVD in T1D

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Study found that the absence of proliferative diabetic retinopathy in those with stage 3b chronic kidney disease is associated with a lower prevalence of cardiovascular disease in patients with long duration of type 1 diabetes.

Prevalence, Effect of Undetected Diabetes in Percutaneous Coronary Intervention

Prevalence, Effect of Undetected Diabetes in Percutaneous Coronary Intervention

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Abnormal glucose metabolism was detected in 1 out of 3 patients with nondiabetic percutaneous coronary intervention and was independently associated with a significantly higher event risk.

Sulfonylureas and Risk of Sudden Cardiac Arrest, Ventricular Arrhythmia Examined

Sulfonylureas and Risk of Sudden Cardiac Arrest, Ventricular Arrhythmia Examined

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Study examined the association between individual antidiabetic sulfonylureas and outpatient-originating sudden cardiac arrest and ventricular arrhythmia.

Increased Adiposity Raises Myocardial Infarction Risk More in Women

Increased Adiposity Raises Myocardial Infarction Risk More in Women

Increases in waist circumference and waist-to-hip ratio are associated with a greater excess risk of myocardial infarction in women than men.

Effect of Fenofibrate Varies Widely in Type 2 Diabetes

Effect of Fenofibrate Varies Widely in Type 2 Diabetes

The method of individualized treatment effect prediction of fenofibrate on major cardiovascular events risk reduction in T2D can be used to guide clinical decision-making.

Predicting Mortality Following Acute Myocardial Infarction in Diabetes

Predicting Mortality Following Acute Myocardial Infarction in Diabetes

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The acute-to-chronic glycemic ratio provided better prognostic insight with regard to in-hospital mortality and morbidity outcomes compared with glycemia levels at hospital admission in patients with diabetes who had an acute myocardial infarction.

Prior Authorization Requirements Greater for PCSK9 Inhibitors

Prior Authorization Requirements Greater for PCSK9 Inhibitors

Prior authorization requirements are greater for proprotein convertase subtilisin/kexin type 9 inhibitors than for other cardiometabolic drugs.

Case: A 67-Year-Old Man With Shortness of Breath After Wildfires

Case: A 67-Year-Old Man With Shortness of Breath After Wildfires

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A patient living near an area experiencing frequent wildfires is concerned about the potential negative effect that the wildfires may have on his health.

T2D May Play a Protective Role Against Developing Aortic Diseases

T2D May Play a Protective Role Against Developing Aortic Diseases

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The novel findings in this study suggest that patients with type 2 diabetes have a significantly reduced risk for short-term mortality after hospitalization for aortic aneurysm compared with population-based control subjects.

Reducing CV Risk in Patients With Rheumatoid Arthritis and Diabetes

Reducing CV Risk in Patients With Rheumatoid Arthritis and Diabetes

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Abatacept conferred a greater reduction in cardiovascular risk compared with tumor necrosis factor inhibitors in patients with rheumatoid arthritis and diabetes.

Little Effect on Metabolic Risk Factors With Addition of SSRIs to Antipsychotics

Little Effect on Metabolic Risk Factors With Addition of SSRIs to Antipsychotics

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A combination of selective serotonin reuptake inhibitors and antipsychotics does not lead to further deterioration of metabolic variables; however, metabolic monitoring should be performed.

Updated <I>Standards of Medical Care in Diabetes</I> Focuses on Cardiovascular Disease

Updated Standards of Medical Care in Diabetes Focuses on Cardiovascular Disease

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ADA's recommendations reflect the latest advances in evidence-based research to improve care for millions of people with diabetes.

Duration of Prediabetes, Diabetes Independently Associated With Subclinical Atherosclerosis, Cardiac Dysfunction

Duration of Prediabetes, Diabetes Independently Associated With Subclinical Atherosclerosis, Cardiac Dysfunction

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Data emphasize the importance of early identification and management of those at risk for diabetes and prediabetes in order to limit exposure to the adverse cardiovascular effects of a longer duration of these conditions.

Lower Bone Mineral Density May Increase Intracranial Aneurysm Risk

Lower Bone Mineral Density May Increase Intracranial Aneurysm Risk

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A lower bone mineral density in the lumbar spine, femoral neck, and hip is associated with an increased risk for intracranial aneurysm.

Gestational Diabetes May Increase Risk for Hypertension, Ischemic Heart Disease, T2D

Gestational Diabetes May Increase Risk for Hypertension, Ischemic Heart Disease, T2D

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Clinical guidelines should include postpartum screening and management for all cardiovascular risk factors in women diagnosed with gestational diabetes and not restrict it to diabetes.

Does Bariatric Surgery Reduce CVD Risk Factors in Adolescents?

Does Bariatric Surgery Reduce CVD Risk Factors in Adolescents?

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Weight loss after bariatric surgery in adolescents predicts the degree of longitudinal improvement in elevated high-sensitivity C-reactive protein, hyperinsulinemia, dyslipidemia, and diabetes.

New Recommendations for High Blood Pressure Management, Prevention

New Recommendations for High Blood Pressure Management, Prevention

New recommendations have been developed for the prevention, detection, evaluation, and management of high blood pressure.

Adding Ezetimibe to Statin Therapy: Cardiovascular Outcomes in Diabetes

Adding Ezetimibe to Statin Therapy: Cardiovascular Outcomes in Diabetes

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In patients with an acute coronary syndrome and LDL-C >50 mg/dL, healthcare providers should consider adding ezetimibe to statin therapy to reduce the risk of cardiovascular events.

Plasma Volume Changes Mediate Risk of CV Mortality With Empagliflozin

Plasma Volume Changes Mediate Risk of CV Mortality With Empagliflozin

The reduction in risk of cardiovascular death with empagliflozin is most mediated by changes in hematocrit and hemoglobin.

Higher Risk for Stroke, MI in Patients With Gout, Diabetes

Higher Risk for Stroke, MI in Patients With Gout, Diabetes

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Patients with both gout and diabetes are at a much higher risk for stroke and myocardial infarction than with diabetes alone.

Intensive Blood Pressure Lowering Reduces CV Events Similarly in Patients With/Without T2D

Intensive Blood Pressure Lowering Reduces CV Events Similarly in Patients With/Without T2D

Researchers assessed the effect of both type 2 diabetes and baseline cardiovascular disease risk on the treatment effect of intensive blood pressure lowering based on data and pooled analysis from 14,094 patients.

CV Event Prediction, Risk Assessment in Type 2 Diabetes

CV Event Prediction, Risk Assessment in Type 2 Diabetes

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Risk of cardiovascular events in people with type 2 diabetes and subgroups of coronary artery disease was examined.

Subclinical Primary Aldosteronism Increases Hypertension Risk in Normotensive Patients

Subclinical Primary Aldosteronism Increases Hypertension Risk in Normotensive Patients

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Future studies using a renin phenotype-driven approach may efficiently identify new-onset or mild hypertension.

Urinary Albumin-to-Creatinine Ratio Aids CV Risk Assessment in T2D

Urinary Albumin-to-Creatinine Ratio Aids CV Risk Assessment in T2D

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Urinary albumin-to-creatinine ratio can be independently associated with various adverse CV outcomes.

Coronary Artery Bypass Grafting: Preferred Method of Revascularization in Diabetes

Coronary Artery Bypass Grafting: Preferred Method of Revascularization in Diabetes

In patients with diabetes, coronary artery bypass grafting may be the preferred method of revascularization, with lower rates of major adverse cardiac or cerebrovascular events.

Physical Activity, Sedentary Time May Increase Cardiometabolic Risk Markers in Prediabetes

Physical Activity, Sedentary Time May Increase Cardiometabolic Risk Markers in Prediabetes

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A study sought to clarify whether total physical activity during the day is equally as important as achieving high levels of intensity associated with moderate-to-vigorous physical activity.

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