Bone Metabolism

Poorly Controlled Rheumatoid Arthritis Increases T2D Risk

Poorly Controlled Rheumatoid Arthritis Increases T2D Risk

Type 2 diabetes is significantly underdiagnosed and undertreated in patients with rheumatoid arthritis.

Examining the Relationship Between Linear Growth and Bone Accrual in Children and Adolescents

Examining the Relationship Between Linear Growth and Bone Accrual in Children and Adolescents

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Height gains "substantially outpaced" bone mineral content gains during childhood, potentially leading to increased fracture risk.

Romosozumab Plus Alendronate Reduces Fracture Risk in Postmenopausal Osteoporosis

Romosozumab Plus Alendronate Reduces Fracture Risk in Postmenopausal Osteoporosis

Risk of new vertebral fracture was reduced among women int he romosozumab-to-alendronate group vs those who took alendronate alone.

BMD and Physical Activity: Examining the Relationship in Class III Obesity

BMD and Physical Activity: Examining the Relationship in Class III Obesity

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Both intensity of physical activity and time spent active can explain variability in femoral neck BMD in people with class III obesity.

New Bone Density Assessment Effectively Predicts Fracture Risk in Children

New Bone Density Assessment Effectively Predicts Fracture Risk in Children

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A femoral stress index assessment evaluates fracture risk in children as effectively as femoral and total body bone mineral density.

Safety, Efficacy of Burosumab vs Placebo for X-Linked Hypophosphatemia Examined

Safety, Efficacy of Burosumab vs Placebo for X-Linked Hypophosphatemia Examined

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In a double-blind multicenter study, researchers examined the safety and efficacy of burosumab for X-linked hypophosphatemia.

Protective Effect of Hypoxia on Bone Health in Menopausal Women

Protective Effect of Hypoxia on Bone Health in Menopausal Women

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Intermittent hypoxia in obstructive sleep apnea was found to decrease the chances of bone health decline in menopausal women.

Can Anxiety or Depression Determine Low BMD in Patients With Anorexia?

Can Anxiety or Depression Determine Low BMD in Patients With Anorexia?

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Both anxiety and depression scores are associated with low BMD.

Single BMD, Fracture History Predicts Long-Term Fracture Risk in Older Women

Single BMD, Fracture History Predicts Long-Term Fracture Risk in Older Women

A single bone mineral density measure and fracture history can predict long-term fracture risk in older women.

K-Postn Assay New Tool to Assess Fracture Risk in Postmenopausal Women

K-Postn Assay New Tool to Assess Fracture Risk in Postmenopausal Women

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According to a study published in the Journal of Bone and Mineral Research, researchers hypothesized that serum K-Postn levels may be able to predict low-trauma fractures.

Effects of Cross-Sex Hormone Therapy on BMD of Transgender People

Effects of Cross-Sex Hormone Therapy on BMD of Transgender People

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The effect of 1 year of cross-sex hormone therapy on bone mineral density was examined in transgender men and women.

Vitamin B, Folic Acid Effect on Fracture Risk in Women With CV Disease

Vitamin B, Folic Acid Effect on Fracture Risk in Women With CV Disease

Daily supplementation with B vitamins and folic acid does not affect fracture risk for women with preexisting CV disease.

BMD Loss Slowed With Delayed Antiretroviral Therapy in HIV

BMD Loss Slowed With Delayed Antiretroviral Therapy in HIV

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Researchers examined the benefits and risks associated with delaying ART initiation to slow bone mineral density loss.

BMD of Femoral Neck Declines Twice as Fast in HIV-Infected Women

BMD of Femoral Neck Declines Twice as Fast in HIV-Infected Women

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Bone mineral density of the femoral neck, a significant predictor of fracture risk, declined nearly twice as quickly in HIV-infected women compared with HIV-infected men.

Managing Osteoporosis With Type 2 Diabetes: An Expert Opinion

Managing Osteoporosis With Type 2 Diabetes: An Expert Opinion

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Researchers conducted a systematic review of available literature to create a guide for optimal management of patients with type 2 diabetes and osteoporosis.

FDA Requests Additional Data in Romosozumab Biologics License Application

FDA Requests Additional Data in Romosozumab Biologics License Application

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The FDA has requested data from 2 additional phase 3 clinical trials analyzing the safety and effectiveness of romosozumab, Amgen, Inc. and UCB's joint osteoporosis drug.

Bone Mineral Density Decline With Immediate Antiretroviral Tx in HIV

Bone Mineral Density Decline With Immediate Antiretroviral Tx in HIV

Changes in bone mineral density at 1 year were similar in the immediate and delayed ART groups.

Parathyroidectomy for Secondary, Tertiary Hyperparathyroidism Increases Morbidity and Mortality

Parathyroidectomy for Secondary, Tertiary Hyperparathyroidism Increases Morbidity and Mortality

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After parathyroidectomy, morbidity and mortality rates were considerably higher in patients with secondary and tertiary vs primary hyperparathyroidism.

Does Sedative Use Increase Repeat Fall Risk?

Does Sedative Use Increase Repeat Fall Risk?

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Daytime sleepiness and poor quality of sleep affect recurrent fall risk in the elderly.

Hand Osteoarthritis and Type 1 Diabetes: Is There A Connection?

Hand Osteoarthritis and Type 1 Diabetes: Is There A Connection?

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Hand pain, disability, and stiffness were common in long-term type 1 diabetes.

Colecalciferol Did Not Reduce Fracture or Fall Risks

Colecalciferol Did Not Reduce Fracture or Fall Risks

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Healthy middle-age patients who took colecalciferol did not have a reduced risk for fall or fracture.

Fracture Risk Cut With Low Level of Physical Activity

Fracture Risk Cut With Low Level of Physical Activity

Twenty minutes per day of walking or bicycling were associated with a lower rate of fracture.

Examining the Relationship Between Weight Loss and Knee Degeneration

Examining the Relationship Between Weight Loss and Knee Degeneration

Participants who lost between 5% and 10% or more than 10% of their body weight slowed knee joint degeneration, compared to those who maintained their current weight.

Ertugliflozin Plus Metformin Improves Glycemic Control in Type 2 Diabetes

Ertugliflozin Plus Metformin Improves Glycemic Control in Type 2 Diabetes

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A randomized double-blind trial examined the safety and efficacy of ertugliflozin plus metformin for inadequately controlled type 2 diabetes.

Sleeping Pills and Fracture Risk: Is There A Link?

Sleeping Pills and Fracture Risk: Is There A Link?

A 2.5 times higher fracture risk was noted among elderly patients taking sleeping pills.

Fracture Risk Decreases, Bone Mineral Density Increases With Long-Term Denosumab

Fracture Risk Decreases, Bone Mineral Density Increases With Long-Term Denosumab

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Long-term denosumab increased bone mineral density in postmenopausal women.

ACOG Guidelines Urge Screening for Female Athlete Triad

ACOG Guidelines Urge Screening for Female Athlete Triad

The female athlete triad includes low energy availability, menstrual dysfunction, and low bone density.

Increasing Bone Mineral Density in Older Men

Increasing Bone Mineral Density in Older Men

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After 1 year of therapy, men who underwent testosterone therapy experienced improvement in bone mineral density and mood.

ACP: Updated Osteoporosis Treatment Guidelines

ACP: Updated Osteoporosis Treatment Guidelines

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An update to the 2008 ACP osteoporosis treatment guidelines focuses on treating low bone density and osteoporosis in an effort to prevent fractures.

Osteoporosis, Fracture Risk Elevated With Tuberculosis

Osteoporosis, Fracture Risk Elevated With Tuberculosis

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Tuberculosis was identified as an independent risk factor associated with incident osteoporosis.

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