Bone Metabolism

Long-Term Safety of Denosumab in Postmenopausal Osteoperosis

Long-Term Safety of Denosumab in Postmenopausal Osteoperosis

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The most common adverse events associated with long-term denosumab use were back, musculoskeletal, or extremity pain, hypercholesterolemia, and cystis.

Osteoporosis Care Quality Most Consistently Predicted By Primary Care

Osteoporosis Care Quality Most Consistently Predicted By Primary Care

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The most important predictor for use of osteoporosis care was receiving primary care services within 6 months following hip fracture.

Is Normal Basal Bone Metabolism Vitamin D-Dependent in Postmenopausal Women With T2D?

Is Normal Basal Bone Metabolism Vitamin D-Dependent in Postmenopausal Women With T2D?

Findings in postmenopausal women with T2DM; correlations prominent in those with higher 25(OH)D

DXA-Visceral Adipose Tissue Measurements in Atherosclerotic CVD Risk Assessment

DXA-Visceral Adipose Tissue Measurements in Atherosclerotic CVD Risk Assessment

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Neither DXA-visceral adipose tissue nor android-gynoid fat mass ratios were associated with atherosclerotic cardiovascular disease events.

Leg Positioning During Lumbar Spine DXA

Leg Positioning During Lumbar Spine DXA

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Researchers evaluated trabecular bone scores in more than 100 women during either "legs up" or "legs down" dual energy x-ray absorptiometry scans.

Bone Age in Children as Assessed by Dual-Energy X-Ray and Radiography

Bone Age in Children as Assessed by Dual-Energy X-Ray and Radiography

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Using dual-energy X-ray absorptiometry for bone age assessment complements traditional radiologic assessment.

Accuracy of Trabecular Bone Score to Assess Fragility Fracture Risk in T1D

Accuracy of Trabecular Bone Score to Assess Fragility Fracture Risk in T1D

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Fragility fracture risk increased with older age and decreased with higher bone mineral density in patients with type 1 diabetes.

Is DXA Required to Diagnose Vertebral Fracture in Patients With Low BMD?

Is DXA Required to Diagnose Vertebral Fracture in Patients With Low BMD?

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Researchers compared the efficacy of dual-energy x-ray absorptiometry with lateral x-ray in assessing vertebral fractures.

TeleECHO Clinic Improves Physician Confidence in Osteoporosis Care

TeleECHO Clinic Improves Physician Confidence in Osteoporosis Care

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The Bone Health TeleECHO Clinic helps telementor healthcare professionals and improves osteoporosis care in underserved communities.

Heart Failure Risk Varies With Bone Density and Race

Heart Failure Risk Varies With Bone Density and Race

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Total hip BMD was associated with heart failure risk in black and non-black men, with an interaction by race.

Testosterone Increases Lumbar Spine Volumetric Trabecular BMD in Older Men

Testosterone Increases Lumbar Spine Volumetric Trabecular BMD in Older Men

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Testosterone treatment improved both bone mineral density and strength in older men.

How Does Antenatal Betamethasone Exposure Affect Pediatric Bone Mass?

How Does Antenatal Betamethasone Exposure Affect Pediatric Bone Mass?

The effects of repeat doses of antenatal betamethasone were assessed in 185 eligible pediatric patients.

Anti-fracture Therapy Effectively Prevents Bone Loss in Women Post-Critical Illness

Anti-fracture Therapy Effectively Prevents Bone Loss in Women Post-Critical Illness

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Researchers found that female patients recovering from critical illness respond better to anti-fracture therapy for bone mineral density loss prevention compared with men.

Significant Fracture Burden, Psychological Comorbidities Associated With Hypophosphatasia

Significant Fracture Burden, Psychological Comorbidities Associated With Hypophosphatasia

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Disease burden associated with hypophosphatasia was analyzed in a population of patients utilizing electronic medical records.

Metabolic Bone Toxicity Possible With Certain Hepatitis Antivirals

Metabolic Bone Toxicity Possible With Certain Hepatitis Antivirals

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The long-term effects of several hepatitis virus antivirals on various aspects of bone metabolism are unclear.

Should Trabecular Bone Score Be Used to Assess Bone Quality in Type 2 Diabetes?

Should Trabecular Bone Score Be Used to Assess Bone Quality in Type 2 Diabetes?

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The trabecular bone score may provides an acute, albeit indirect, measurement of bone quality in patients with type 2 diabetes.

Likelihood of Hypertension Increased by Knee Osteoarthritis

Likelihood of Hypertension Increased by Knee Osteoarthritis

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Data were collected from the Osteoarthritis Initiative to examine the relationship between knee osteoarthritis and hypertension.

Does Osteoarthritis Diagnosis Affect Rheumatoid Arthritis Disease Activity Scores?

Does Osteoarthritis Diagnosis Affect Rheumatoid Arthritis Disease Activity Scores?

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Patients with rheumatoid arthritis (RA) were evaluated at a specialized clinic to determine the relationship between knee osteoarthritis and elevated Disease Activity Scores (DAS28).

Hepatitis B Therapy Associated With Abnormal Bone Metabolism

Hepatitis B Therapy Associated With Abnormal Bone Metabolism

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Patients taking tenofovir should aim to maximize the phosphorous in their diet.

Heart Disease, Osteoporosis Risks Up in Young Thyroid Cancer Survivors

Heart Disease, Osteoporosis Risks Up in Young Thyroid Cancer Survivors

Younger survivors of thyroid cancer are at increased risk for certain types of health problems later in life.

Fracture Risk in Psoriatic Arthritis, Psoriasis Examined

Fracture Risk in Psoriatic Arthritis, Psoriasis Examined

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Patients with psoriatic arthritis or psoriasis had an increased prevalence of osteoporosis risk factors.

FDA Clears Point-of-Care Device for Diagnosing Osteoporosis

FDA Clears Point-of-Care Device for Diagnosing Osteoporosis

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Bone Index announced that the Food and Drug Administration (FDA) has granted clearance for the second generation Bindex device model to aid in the diagnosis of osteoporosis.

Bone Density Linked to Vascular Calcification in ESRD

Bone Density Linked to Vascular Calcification in ESRD

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A prospective cohort study in 66 patients with end-stage renal disease was conducted to determine the link between renal and coronary heart diseases.

Alzheimer's Disease: Risk Factor for Hip Fracture

Alzheimer's Disease: Risk Factor for Hip Fracture

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Cardiovascular disease, stroke, diabetes, hip and knee replacements, and both behavioral and mental disorders were also more common in the Alzheimer's disease cohort.

Etelcalcetide Examined in Hemodialysis Patients With Secondary Hyperparathyroidism

Etelcalcetide Examined in Hemodialysis Patients With Secondary Hyperparathyroidism

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Etelcalcetide shows promise for reducing parathyroid hormone in hemodialysis patients with secondary hyperparathyroidism.

Less Frequent Dosing of Bisphosphonate in Patients With Bone Metastases

Less Frequent Dosing of Bisphosphonate in Patients With Bone Metastases

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Less frequent dosing with zoledronic acid does not increase fracture risk in patients with bone metastases.

Hip Fracture Risk in Type 2 Diabetes

Hip Fracture Risk in Type 2 Diabetes

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The association between risk for hip fracture and diabetes was attenuated after accounting for mortality risk.

Long-Term DPP-4 Inhibitor Use Not Associated With Fracture Risk in Type 2 Diabetes

Long-Term DPP-4 Inhibitor Use Not Associated With Fracture Risk in Type 2 Diabetes

For patients with type 2 diabetes, long-term use of dipeptidyl peptidase-4 (DPP-4) inhibitors is not associated with fracture risk.

VIDEO: Clinical Trial Results for Abaloparatide

Lorraine Fitzpatrick, MD, discusses updated results from the ACTIVE phase 3 clinical trial.

The Handoff: Your Week in Endocrinology - 11/25/16

In this week's Handoff, read more about recent FDA approvals, food banks' efforts to improve the healthiness of their donations, and more.

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