Bone Metabolism

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Worsening Diabetes Despite Improved Osteoporosis

Worsening Diabetes Despite Improved Osteoporosis

An older women with type 2 diabetes and osteoporosis experienced improvements with one condition at the expense of the other.

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Oral Bisphosphonate Prescription Trends Shifted After 2008 Recommendations

Oral Bisphosphonate Prescription Trends Shifted After 2008 Recommendations

Two distinct time trends were observed in initiation of oral bisphosphonates in women after the 2008 updated osteoporosis treatment guidelines.

Heart Disease, Osteoporosis Risks Up in Young Thyroid Cancer Survivors

Heart Disease, Osteoporosis Risks Up in Young Thyroid Cancer Survivors

Younger survivors of thyroid cancer are at increased risk for certain types of health problems later in life.

Fracture Risk in Psoriatic Arthritis, Psoriasis Examined

Fracture Risk in Psoriatic Arthritis, Psoriasis Examined

Patients with psoriatic arthritis or psoriasis had an increased prevalence of osteoporosis risk factors.

FDA Clears Point-of-Care Device for Diagnosing Osteoporosis

FDA Clears Point-of-Care Device for Diagnosing Osteoporosis

Bone Index announced that the Food and Drug Administration (FDA) has granted clearance for the second generation Bindex device model to aid in the diagnosis of osteoporosis.

Bone Density Linked to Vascular Calcification in ESRD

Bone Density Linked to Vascular Calcification in ESRD

A prospective cohort study in 66 patients with end-stage renal disease was conducted to determine the link between renal and coronary heart diseases.

Alzheimer's Disease: Risk Factor for Hip Fracture

Alzheimer's Disease: Risk Factor for Hip Fracture

Cardiovascular disease, stroke, diabetes, hip and knee replacements, and both behavioral and mental disorders were also more common in the Alzheimer's disease cohort.

Etelcalcetide Examined in Hemodialysis Patients With Secondary Hyperparathyroidism

Etelcalcetide Examined in Hemodialysis Patients With Secondary Hyperparathyroidism

Etelcalcetide shows promise for reducing parathyroid hormone in hemodialysis patients with secondary hyperparathyroidism.

Malignancy Risk & Vitamin D Deficiency: An Unclear Relationship

Malignancy Risk & Vitamin D Deficiency: An Unclear Relationship

According to the National Cancer Institute, there are not enough available data to establish whether taking vitamin D can prevent cancer.

Less Frequent Dosing of Bisphosphonate in Patients With Bone Metastases

Less Frequent Dosing of Bisphosphonate in Patients With Bone Metastases

Less frequent dosing with zoledronic acid does not increase fracture risk in patients with bone metastases.

Hip Fracture Risk in Type 2 Diabetes

Hip Fracture Risk in Type 2 Diabetes

The association between risk for hip fracture and diabetes was attenuated after accounting for mortality risk.

Long-Term DPP-4 Inhibitor Use Not Associated With Fracture Risk in Type 2 Diabetes

Long-Term DPP-4 Inhibitor Use Not Associated With Fracture Risk in Type 2 Diabetes

For patients with type 2 diabetes, long-term use of dipeptidyl peptidase-4 (DPP-4) inhibitors is not associated with fracture risk.

VIDEO: Clinical Trial Results for Abaloparatide

Lorraine Fitzpatrick, MD, discusses updated results from the ACTIVE phase 3 clinical trial.

The Handoff: Your Week in Endocrinology - 11/25/16

In this week's Handoff, read more about recent FDA approvals, food banks' efforts to improve the healthiness of their donations, and more.

Does Antihypertensive Medication Class Affect Fracture Risk?

Does Antihypertensive Medication Class Affect Fracture Risk?

Researchers compared 3 classes of antihypertensive medication to determine hip and pelvic fracture risk in users vs nonusers.

Bone Health Improved With Menopausal Hormone Therapy

Bone Health Improved With Menopausal Hormone Therapy

The use of menopausal hormone therapy was associated with improved bone mineral density and better bone microarchitecture.

New Osteoporosis Treatment Options on the Horizon

Nancy E. Lane, MD, professor of medicine, at the University of California at Davis School of Medicine, discusses results from the phase 3 ACTIVE trial.

BMI Associated With Hand Osteoarthritis

BMI Associated With Hand Osteoarthritis

Increased body mass index (BMI) may have a moderate effect on hand arthritis.

Vitamin D Supplementation May Have Varying Effects in Pregnancy

Vitamin D Supplementation May Have Varying Effects in Pregnancy

Several factors influence the impact of cholecalciferol supplementation in pregnant women.

Bone Density Lower Among Heavy Cannabis Users

Bone Density Lower Among Heavy Cannabis Users

Heavy cannabis users have lower bone density compared to cigarette smokers.

Stimulant Use Associated With Lower Bone Mass in Children, Teens

Stimulant Use Associated With Lower Bone Mass in Children, Teens

Children and teens who used stimulants for attention-deficit/hyperactivity disorder had lower bone mineral content and bone density than nonusers.

Benefits, Drawbacks of Calorie Restriction in Postmenopausal Women

Benefits, Drawbacks of Calorie Restriction in Postmenopausal Women

Calorie restriction has been shown to increase longevity, but it may also have adverse effects on bone health in postmenopausal women.

Bone Mineral Density Linked to Concentrations of 25(OH)D in Summer

Bone Mineral Density Linked to Concentrations of 25(OH)D in Summer

Summer levels of serum 25-hydroxyvitamin D are associated with bone mineral density of the total hip.

AACE/ACE Updates Postmenopausal Osteoporosis Management Guidelines

AACE/ACE Updates Postmenopausal Osteoporosis Management Guidelines

The American Association of Clinical Endocrinologists (AACE) and the American College of Endocrinology (ACE) announced the publication of new clinical guidelines and an accompanying algorithm to help physicians and other health care professionals with the diagnosis, fracture risk assessment, and treatment of postmenopausal osteoporosis.

Orthogeriatric Model of Care is Cost-Effective for Elderly Patients With Hip Fractures

Orthogeriatric Model of Care is Cost-Effective for Elderly Patients With Hip Fractures

Orthogeriatric-led service was the most effective and cost-effective model of care for men and women aged 83 years.

Experts Issue Call to Action to Change Recent Trends in Osteoporosis Management

Experts Issue Call to Action to Change Recent Trends in Osteoporosis Management

Experts from more than 30 national and international societies have pledged to intensify efforts and collaborate to address the "crisis" in osteoporosis.

Endocrine-Disrupting Chemicals Associated With Reduced Vitamin D Levels

Endocrine-Disrupting Chemicals Associated With Reduced Vitamin D Levels

Phthalates and bisphenol A metabolites were inversely associated with circulating 25-hydroxyvitamin D levels in adults exposed to these chemicals.

Animal Study Shows Crosstalk Between Bone and Muscle Critical to Exercise Adaptation

Animal Study Shows Crosstalk Between Bone and Muscle Critical to Exercise Adaptation

Crosstalk between bone and muscle plays a significant role in exercise adaptation.

FRAME: Romosozumab Decreases Vertebral Fracture Risk in Osteoporosis

FRAME: Romosozumab Decreases Vertebral Fracture Risk in Osteoporosis

The risk for vertebral fracture in women with osteoporosis was significantly lower with romosozumab vs placebo at 12 months.

Yogurt Consumption in Postmenopausal Women May Benefit Bone Health

Yogurt Consumption in Postmenopausal Women May Benefit Bone Health

The combination of calcium, proteins, and probiotics found in yogurt may affect gut microbiota and have a positive effect on bone density.

Trend of Decreasing Hip Fracture Rates in United States May Be Over

Trend of Decreasing Hip Fracture Rates in United States May Be Over

A decline in Medicare reimbursement for DXA testing is one of the factors to higher-than-expected hip fracture rates.

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