Bone Metabolism Archive

Gastric Bypass Surgery Linked to Increased Risk for Nonvertebral Fractures

Gastric Bypass Surgery Linked to Increased Risk for Nonvertebral Fractures

Roux-en Y gastric bypass increased the likelihood of nonvertebral fractures, including hip, wrist, and pelvic fractures.

Effect of Growth Hormone Treatment on BMD in Adults With Prader-Willi Syndrome

Effect of Growth Hormone Treatment on BMD in Adults With Prader-Willi Syndrome

Researchers investigated the effects of growth hormone vs placebo, as well as the effects of sex steroid replacement therapy on bone mineral density in growth hormone-treated young adults with Prader-Willi syndrome who had attained adult height.

Vitamin D Associated With Improved Bone Health in Epilepsy

Vitamin D Associated With Improved Bone Health in Epilepsy

In this review, 2 independent investigators searched clinical trial databases for studies that evaluated the link between vitamin D supplements and bone health in adult patients with epilepsy.

Abatacept May Improve Femoral Neck Bone Mineral Density in Rheumatoid Arthritis

Abatacept May Improve Femoral Neck Bone Mineral Density in Rheumatoid Arthritis

Abatacept was superior at increasing bone mineral density in the femoral neck compared with other biologic disease-modifying antirheumatic drugs, and may offer good efficacy for improving BMD in rheumatoid arthritis.

Osteoporotic Fracture Risk Predicted by Vertebral Trabecular Attenuation on Routine CT

Osteoporotic Fracture Risk Predicted by Vertebral Trabecular Attenuation on Routine CT

Researchers showed that decreased L1 trabecular attenuation is associated with increased risk for future osteoporotic fractures in adult patients aged ≥65 years undergoing abdominopelvic CT scans for other indications.

COX-2 Inhibitors Plus Metformin Lower Joint Replacement Rates in Osteoarthritis With T2D

COX-2 Inhibitors Plus Metformin Lower Joint Replacement Rates in Osteoarthritis With T2D

Researchers compared the effects of combined metformin and COX-2 inhibitor therapy vs COX-2 therapy alone on joint replacement surgery rates.

Damaging Effects of Gastric Bypass Surgery on Bone Mass and Microarchitecture

Damaging Effects of Gastric Bypass Surgery on Bone Mass and Microarchitecture

Researchers observed detrimental effects of RYGB on bone turnover, mass, structure, and strength just 6 months postoperatively, and these effects persisted throughout the duration of the 12-month study.

Effect of Biologic DMARDs on Spinal Fracture Risk in Ankylosing Spondylitis

Effect of Biologic DMARDs on Spinal Fracture Risk in Ankylosing Spondylitis

The use of biologic disease-modifying antirheumatic drugs has no medium-term effect on the risk for spinal fractures among patients with ankylosing spondylitis.

Denosumab May Increase BMD in Women With Primary Hyperparathyroidism

Denosumab May Increase BMD in Women With Primary Hyperparathyroidism

Study assessed the effect of denosumab on bone mineral density and incident fractures in older adults with primary hyperparathyroidism who could not undergo or refused surgery.

Lower Bone Mineral Density May Increase Intracranial Aneurysm Risk

Lower Bone Mineral Density May Increase Intracranial Aneurysm Risk

A lower bone mineral density in the lumbar spine, femoral neck, and hip is associated with an increased risk for intracranial aneurysm.

BMD and Parathyroid Hormone Levels in Pseudohypoparathyroidism 1B

BMD and Parathyroid Hormone Levels in Pseudohypoparathyroidism 1B

Study showed that parathyroid hormone was a significant predictor of lumbar spine bone mineral density Z-score for pseudohypoparathyroidism 1B patients.

Romosozumab Followed by Alendronate Decreases Fracture Risk in Women With Osteoporosis

Romosozumab Followed by Alendronate Decreases Fracture Risk in Women With Osteoporosis

In postmenopausal women at high risk for fracture, treatment with romosozumab for 12 months, followed by alendronate, was associated with significantly fewer hip fractures than treatment with alendronate alone.

Systemic Corticosteroid Use May Increase Fracture Risk in Pediatric Asthma

Systemic Corticosteroid Use May Increase Fracture Risk in Pediatric Asthma

Increased odds of fractures in pediatric patients with asthma may be associated with systemic corticosteroid use, but not with inhaled corticosteroid use.

Trabecular Bone Morphology Changes May Predict Bone Strength in Girls

Trabecular Bone Morphology Changes May Predict Bone Strength in Girls

Study investigated the correlations between age and body composition with trabecular morphology in a cohort of healthy girls age 9 to 18.

Fracture Risk in Postmenopausal Women With Osteoporosis May Improve With Growth Hormone Therapy

Fracture Risk in Postmenopausal Women With Osteoporosis May Improve With Growth Hormone Therapy

A recent literature review and meta-analysis indicates that growth hormone therapy may reduce the risk for fracture in patients with osteoporosis.

Calcium, Vitamin D Supplements Do Not Reduce Fracture Risk in Older Adults

Calcium, Vitamin D Supplements Do Not Reduce Fracture Risk in Older Adults

New findings do not support routine vitamin D and calcium supplementation in community-dwelling older adults for lowering the incidence of osteoporosis-related fractures.

Prevention of Bone Mineral Density Loss Needed in Epilepsy

Prevention of Bone Mineral Density Loss Needed in Epilepsy

Researchers conducted a long-term follow-up study to determine whether BMD loss, osteoporosis, and fractures were successfully treated or prevented in an urban population of patients with epilepsy and reduced bone density.

Teriparatide More Effective Than Risedronate in Osteoporotic Fractures

Teriparatide More Effective Than Risedronate in Osteoporotic Fractures

Teriparatide is associated with a lower risk for new vertebral and clinical fractures compared with risedronate in post-menopausal women being treated for severe osteoporosis.

Insulin Associated With BMD Loss at Femoral Neck in Women With T2D

Insulin Associated With BMD Loss at Femoral Neck in Women With T2D

Bone mineral density was evaluated annually of the lumbar spine and femoral neck.

Alendronate With Glucocorticoids Lowers Nonvertebral Fracture Risk

Alendronate With Glucocorticoids Lowers Nonvertebral Fracture Risk

The association between alendronate use and nonvertebral fracture was strongest in patients who received high doses of glucocorticoid.

Prolonged Antiresorptive Activity With Zoledronate in Postmenopausal Osteopenia

Prolonged Antiresorptive Activity With Zoledronate in Postmenopausal Osteopenia

In a randomized multidose trial, single doses of zoledronate (1-5 mg) prolonged antiresorptive activity ≥3 years in postmenopausal women with osteopenia.

Higher Prevalence of Sarcopenic Obesity in Osteoarthritis Than Rheumatoid Arthritis

Higher Prevalence of Sarcopenic Obesity in Osteoarthritis Than Rheumatoid Arthritis

The prevalence of sarcopenia — particularly in combination with ostepenia — increases with age, and sarcopenic obesity may be underrecognized, despite its impact in patients with rheumatic diseases.

Risks Associated With Denosumab Discontinuation

Risks Associated With Denosumab Discontinuation

Risk of vertebral fractures may be increased with discontinuation of denosumab therapy.

USPSTF: Screening Recommendations Updated for Preventing Osteoporotic Fractures

USPSTF: Screening Recommendations Updated for Preventing Osteoporotic Fractures

The task force recommends screening for osteoporosis with bone measurement testing to prevent osteoporotic fractures in women ≥65 years and postmenopausal women.

Predicting Hypocalcemia in Children Following Thyroidectomy: Is PTH Level Useful?

Predicting Hypocalcemia in Children Following Thyroidectomy: Is PTH Level Useful?

While parathyroid hormone levels may be used to anticipate calcium decline, a "normal" PTH level does not always correctly predict postoperative calcium level.

Update on Vitamin D and Calcium Supplements for Reducing Fracture Risk

Update on Vitamin D and Calcium Supplements for Reducing Fracture Risk

The USPSTF commissioned a systematic evidence review on vitamin D, calcium, and combined supplementation for the primary prevention of fractures in community-dwelling adults.

Poorly Controlled Rheumatoid Arthritis Increases T2D Risk

Poorly Controlled Rheumatoid Arthritis Increases T2D Risk

Type 2 diabetes is significantly underdiagnosed and undertreated in patients with rheumatoid arthritis.

Examining the Relationship Between Linear Growth and Bone Accrual in Children and Adolescents

Examining the Relationship Between Linear Growth and Bone Accrual in Children and Adolescents

Height gains "substantially outpaced" bone mineral content gains during childhood, potentially leading to increased fracture risk.

BMD and Physical Activity: Examining the Relationship in Class III Obesity

BMD and Physical Activity: Examining the Relationship in Class III Obesity

Both intensity of physical activity and time spent active can explain variability in femoral neck BMD in people with class III obesity.

New Bone Density Assessment Effectively Predicts Fracture Risk in Children

New Bone Density Assessment Effectively Predicts Fracture Risk in Children

A femoral stress index assessment evaluates fracture risk in children as effectively as femoral and total body bone mineral density.

Safety, Efficacy of Burosumab vs Placebo for X-Linked Hypophosphatemia Examined

Safety, Efficacy of Burosumab vs Placebo for X-Linked Hypophosphatemia Examined

In a double-blind multicenter study, researchers examined the safety and efficacy of burosumab for X-linked hypophosphatemia.

Can Anxiety or Depression Determine Low BMD in Patients With Anorexia?

Can Anxiety or Depression Determine Low BMD in Patients With Anorexia?

Both anxiety and depression scores are associated with low BMD.

Protective Effect of Hypoxia on Bone Health in Menopausal Women

Protective Effect of Hypoxia on Bone Health in Menopausal Women

Intermittent hypoxia in obstructive sleep apnea was found to decrease the chances of bone health decline in menopausal women.

Single BMD, Fracture History Predicts Long-Term Fracture Risk in Older Women

Single BMD, Fracture History Predicts Long-Term Fracture Risk in Older Women

A single bone mineral density measure and fracture history can predict long-term fracture risk in older women.

K-Postn Assay New Tool to Assess Fracture Risk in Postmenopausal Women

K-Postn Assay New Tool to Assess Fracture Risk in Postmenopausal Women

According to a study published in the Journal of Bone and Mineral Research, researchers hypothesized that serum K-Postn levels may be able to predict low-trauma fractures.

Effects of Cross-Sex Hormone Therapy on BMD of Transgender People

Effects of Cross-Sex Hormone Therapy on BMD of Transgender People

The effect of 1 year of cross-sex hormone therapy on bone mineral density was examined in transgender men and women.

Vitamin B, Folic Acid Effect on Fracture Risk in Women With CV Disease

Vitamin B, Folic Acid Effect on Fracture Risk in Women With CV Disease

Daily supplementation with B vitamins and folic acid does not affect fracture risk for women with preexisting CV disease.

BMD Loss Slowed With Delayed Antiretroviral Therapy in HIV

BMD Loss Slowed With Delayed Antiretroviral Therapy in HIV

Researchers examined the benefits and risks associated with delaying ART initiation to slow bone mineral density loss.

BMD of Femoral Neck Declines Twice as Fast in HIV-Infected Women

BMD of Femoral Neck Declines Twice as Fast in HIV-Infected Women

Bone mineral density of the femoral neck, a significant predictor of fracture risk, declined nearly twice as quickly in HIV-infected women compared with HIV-infected men.

Managing Osteoporosis With Type 2 Diabetes: An Expert Opinion

Managing Osteoporosis With Type 2 Diabetes: An Expert Opinion

Researchers conducted a systematic review of available literature to create a guide for optimal management of patients with type 2 diabetes and osteoporosis.

FDA Requests Additional Data in Romosozumab Biologics License Application

FDA Requests Additional Data in Romosozumab Biologics License Application

The FDA has requested data from 2 additional phase 3 clinical trials analyzing the safety and effectiveness of romosozumab, Amgen, Inc. and UCB's joint osteoporosis drug.

Bone Mineral Density Decline With Immediate Antiretroviral Tx in HIV

Bone Mineral Density Decline With Immediate Antiretroviral Tx in HIV

Changes in bone mineral density at 1 year were similar in the immediate and delayed ART groups.

Parathyroidectomy for Secondary, Tertiary Hyperparathyroidism Increases Morbidity and Mortality

Parathyroidectomy for Secondary, Tertiary Hyperparathyroidism Increases Morbidity and Mortality

After parathyroidectomy, morbidity and mortality rates were considerably higher in patients with secondary and tertiary vs primary hyperparathyroidism.

Does Sedative Use Increase Repeat Fall Risk?

Does Sedative Use Increase Repeat Fall Risk?

Daytime sleepiness and poor quality of sleep affect recurrent fall risk in the elderly.

Hand Osteoarthritis and Type 1 Diabetes: Is There A Connection?

Hand Osteoarthritis and Type 1 Diabetes: Is There A Connection?

Hand pain, disability, and stiffness were common in long-term type 1 diabetes.

Colecalciferol Did Not Reduce Fracture or Fall Risks

Colecalciferol Did Not Reduce Fracture or Fall Risks

Healthy middle-age patients who took colecalciferol did not have a reduced risk for fall or fracture.

Fracture Risk Cut With Low Level of Physical Activity

Fracture Risk Cut With Low Level of Physical Activity

Twenty minutes per day of walking or bicycling were associated with a lower rate of fracture.

Examining the Relationship Between Weight Loss and Knee Degeneration

Examining the Relationship Between Weight Loss and Knee Degeneration

Participants who lost between 5% and 10% or more than 10% of their body weight slowed knee joint degeneration, compared to those who maintained their current weight.

Ertugliflozin Plus Metformin Improves Glycemic Control in Type 2 Diabetes

Ertugliflozin Plus Metformin Improves Glycemic Control in Type 2 Diabetes

A randomized double-blind trial examined the safety and efficacy of ertugliflozin plus metformin for inadequately controlled type 2 diabetes.

Sleeping Pills and Fracture Risk: Is There A Link?

Sleeping Pills and Fracture Risk: Is There A Link?

A 2.5 times higher fracture risk was noted among elderly patients taking sleeping pills.

Fracture Risk Decreases, Bone Mineral Density Increases With Long-Term Denosumab

Fracture Risk Decreases, Bone Mineral Density Increases With Long-Term Denosumab

Long-term denosumab increased bone mineral density in postmenopausal women.

ACOG Guidelines Urge Screening for Female Athlete Triad

ACOG Guidelines Urge Screening for Female Athlete Triad

The female athlete triad includes low energy availability, menstrual dysfunction, and low bone density.

Increasing Bone Mineral Density in Older Men

Increasing Bone Mineral Density in Older Men

After 1 year of therapy, men who underwent testosterone therapy experienced improvement in bone mineral density and mood.

ACP: Updated Osteoporosis Treatment Guidelines

ACP: Updated Osteoporosis Treatment Guidelines

An update to the 2008 ACP osteoporosis treatment guidelines focuses on treating low bone density and osteoporosis in an effort to prevent fractures.

Osteoporosis, Fracture Risk Elevated With Tuberculosis

Osteoporosis, Fracture Risk Elevated With Tuberculosis

Tuberculosis was identified as an independent risk factor associated with incident osteoporosis.

Oral Contraceptives May Reduce Fracture Risk

Oral Contraceptives May Reduce Fracture Risk

Women who had taken oral contraceptives for more than 5 years had the lowest risk for fracture.

Osteoporosis Treatment Approaches in Women vs Men

Osteoporosis Treatment Approaches in Women vs Men

A review of osteoporosis diagnosis, treatment, and management in both men and women.

Does Aerobic-Resistance Exercise Benefit Seniors With Obesity?

Does Aerobic-Resistance Exercise Benefit Seniors With Obesity?

At 6 months of exercise intervention, physical performance test scores increased 21% in the combination exercise group, while scores in the control group remained largely the same.

Benefits of Osteoporosis Pharmacotherapy Misunderstood Among Older Women

Benefits of Osteoporosis Pharmacotherapy Misunderstood Among Older Women

Eighty-four percent of survey respondents did not undergo osteoporosis pharmacotherapy following an osteoporosis-related fracture.

FDA Approves Abaloparatide for Fragility Fracture in Postmenopausal Women With Osteoporosis

FDA Approves Abaloparatide for Fragility Fracture in Postmenopausal Women With Osteoporosis

Tymlos approval was based on the results of the ACTIVE and ACTIVExtension trials.

Denosumab-induced Prolonged Hypocalcemia: A Case Study

Denosumab-induced Prolonged Hypocalcemia: A Case Study

Investigators examined an 83-year-old male patient who developed severe hypocalcemia induced by denosumab.

HIV-Induced Osteoporosis Detected Using Bone Ultrasonography

HIV-Induced Osteoporosis Detected Using Bone Ultrasonography

Bone ultrasonography is able to detect tenofovir-induced bone loss in patients with HIV.

Bone Mineral Density Changes Related to Adrenal Incidentalomas in Menopausal Women

Bone Mineral Density Changes Related to Adrenal Incidentalomas in Menopausal Women

After 24 months, bone mineral density was statistically different from baseline.

Physical Activity, Sedentary Time and Bone Strength Association in Teens

Physical Activity, Sedentary Time and Bone Strength Association in Teens

Moderate-to-vigorous physical activity was found to be an independent predictor of bone strength in adolescents.

Long-Term Safety of Denosumab in Postmenopausal Osteoperosis

Long-Term Safety of Denosumab in Postmenopausal Osteoperosis

The most common adverse events associated with long-term denosumab use were back, musculoskeletal, or extremity pain, hypercholesterolemia, and cystis.

Osteoporosis Care Quality Most Consistently Predicted By Primary Care

Osteoporosis Care Quality Most Consistently Predicted By Primary Care

The most important predictor for use of osteoporosis care was receiving primary care services within 6 months following hip fracture.

Is Normal Basal Bone Metabolism Vitamin D-Dependent in Postmenopausal Women With T2D?

Is Normal Basal Bone Metabolism Vitamin D-Dependent in Postmenopausal Women With T2D?

Findings in postmenopausal women with T2DM; correlations prominent in those with higher 25(OH)D

Is DXA Required to Diagnose Vertebral Fracture in Patients With Low BMD?

Is DXA Required to Diagnose Vertebral Fracture in Patients With Low BMD?

Researchers compared the efficacy of dual-energy x-ray absorptiometry with lateral x-ray in assessing vertebral fractures.

Accuracy of Trabecular Bone Score to Assess Fragility Fracture Risk in T1D

Accuracy of Trabecular Bone Score to Assess Fragility Fracture Risk in T1D

Fragility fracture risk increased with older age and decreased with higher bone mineral density in patients with type 1 diabetes.

Bone Age in Children as Assessed by Dual-Energy X-Ray and Radiography

Bone Age in Children as Assessed by Dual-Energy X-Ray and Radiography

Using dual-energy X-ray absorptiometry for bone age assessment complements traditional radiologic assessment.

Leg Positioning During Lumbar Spine DXA

Leg Positioning During Lumbar Spine DXA

Researchers evaluated trabecular bone scores in more than 100 women during either "legs up" or "legs down" dual energy x-ray absorptiometry scans.

DXA-Visceral Adipose Tissue Measurements in Atherosclerotic CVD Risk Assessment

DXA-Visceral Adipose Tissue Measurements in Atherosclerotic CVD Risk Assessment

Neither DXA-visceral adipose tissue nor android-gynoid fat mass ratios were associated with atherosclerotic cardiovascular disease events.

TeleECHO Clinic Improves Physician Confidence in Osteoporosis Care

TeleECHO Clinic Improves Physician Confidence in Osteoporosis Care

The Bone Health TeleECHO Clinic helps telementor healthcare professionals and improves osteoporosis care in underserved communities.

Heart Failure Risk Varies With Bone Density and Race

Heart Failure Risk Varies With Bone Density and Race

Total hip BMD was associated with heart failure risk in black and non-black men, with an interaction by race.

Testosterone Increases Lumbar Spine Volumetric Trabecular BMD in Older Men

Testosterone Increases Lumbar Spine Volumetric Trabecular BMD in Older Men

Testosterone treatment improved both bone mineral density and strength in older men.

How Does Antenatal Betamethasone Exposure Affect Pediatric Bone Mass?

How Does Antenatal Betamethasone Exposure Affect Pediatric Bone Mass?

The effects of repeat doses of antenatal betamethasone were assessed in 185 eligible pediatric patients.

Anti-fracture Therapy Effectively Prevents Bone Loss in Women Post-Critical Illness

Anti-fracture Therapy Effectively Prevents Bone Loss in Women Post-Critical Illness

Researchers found that female patients recovering from critical illness respond better to anti-fracture therapy for bone mineral density loss prevention compared with men.

Significant Fracture Burden, Psychological Comorbidities Associated With Hypophosphatasia

Significant Fracture Burden, Psychological Comorbidities Associated With Hypophosphatasia

Disease burden associated with hypophosphatasia was analyzed in a population of patients utilizing electronic medical records.

Do Bone Turnover Markers Predict Vertebral Fracture Risk Post-Alendronate Discontinuation?

Do Bone Turnover Markers Predict Vertebral Fracture Risk Post-Alendronate Discontinuation?

Study examines the predictive value for vertebral fractures of bone mineral density and bone turnover markers after a 5-year drug holiday.

Metabolic Bone Toxicity Possible With Certain Hepatitis Antivirals

Metabolic Bone Toxicity Possible With Certain Hepatitis Antivirals

The long-term effects of several hepatitis virus antivirals on various aspects of bone metabolism are unclear.

Bisphosphonate Drug Holiday Increases Fracture Risk in Postmenopausal Women

Bisphosphonate Drug Holiday Increases Fracture Risk in Postmenopausal Women

The risk of developing fracture in postmenopausal women with osteoporosis who discontinued bisphosphonate therapy was evaluated in a retrospective study.

Should Trabecular Bone Score Be Used to Assess Bone Quality in Type 2 Diabetes?

Should Trabecular Bone Score Be Used to Assess Bone Quality in Type 2 Diabetes?

The trabecular bone score may provides an acute, albeit indirect, measurement of bone quality in patients with type 2 diabetes.

Likelihood of Hypertension Increased by Knee Osteoarthritis

Likelihood of Hypertension Increased by Knee Osteoarthritis

Data were collected from the Osteoarthritis Initiative to examine the relationship between knee osteoarthritis and hypertension.

Does Osteoarthritis Diagnosis Affect Rheumatoid Arthritis Disease Activity Scores?

Does Osteoarthritis Diagnosis Affect Rheumatoid Arthritis Disease Activity Scores?

Patients with rheumatoid arthritis (RA) were evaluated at a specialized clinic to determine the relationship between knee osteoarthritis and elevated Disease Activity Scores (DAS28).

Hepatitis B Therapy Associated With Abnormal Bone Metabolism

Hepatitis B Therapy Associated With Abnormal Bone Metabolism

Patients taking tenofovir should aim to maximize the phosphorous in their diet.

Risk of Mortality Post-Fragility Fracture Is Sex Dependent

Risk of Mortality Post-Fragility Fracture Is Sex Dependent

Ankle fractures presented similar mortality rates between men and women, while other types of fractures had higher mortality rates among men.

Nonvertebral Fracture Risk After Roux-en-Y Gastric Bypass

Nonvertebral Fracture Risk After Roux-en-Y Gastric Bypass

Researchers examined the nonvertebral fracture risk in adults with obesity who underwent Roux-en-Y gastric bypass vs adjustable gastric banding.

Older Men With Low Total, Bioavailable Testosterone at Increased Risk for Falls

Older Men With Low Total, Bioavailable Testosterone at Increased Risk for Falls

Incident falls were linked with total testosterone and bioavailable levels of testosterone after adjusting for age and prevalent falls.

Oral Bisphosphonate Prescription Trends Shifted After 2008 Recommendations

Oral Bisphosphonate Prescription Trends Shifted After 2008 Recommendations

Two distinct time trends were observed in initiation of oral bisphosphonates in women after the 2008 updated osteoporosis treatment guidelines.

Heart Disease, Osteoporosis Risks Up in Young Thyroid Cancer Survivors

Heart Disease, Osteoporosis Risks Up in Young Thyroid Cancer Survivors

Younger survivors of thyroid cancer are at increased risk for certain types of health problems later in life.

Fracture Risk in Psoriatic Arthritis, Psoriasis Examined

Fracture Risk in Psoriatic Arthritis, Psoriasis Examined

Patients with psoriatic arthritis or psoriasis had an increased prevalence of osteoporosis risk factors.

FDA Clears Point-of-Care Device for Diagnosing Osteoporosis

FDA Clears Point-of-Care Device for Diagnosing Osteoporosis

Bone Index announced that the Food and Drug Administration (FDA) has granted clearance for the second generation Bindex device model to aid in the diagnosis of osteoporosis.

Bone Density Linked to Vascular Calcification in ESRD

Bone Density Linked to Vascular Calcification in ESRD

A prospective cohort study in 66 patients with end-stage renal disease was conducted to determine the link between renal and coronary heart diseases.

Alzheimer's Disease: Risk Factor for Hip Fracture

Alzheimer's Disease: Risk Factor for Hip Fracture

Cardiovascular disease, stroke, diabetes, hip and knee replacements, and both behavioral and mental disorders were also more common in the Alzheimer's disease cohort.

Etelcalcetide Examined in Hemodialysis Patients With Secondary Hyperparathyroidism

Etelcalcetide Examined in Hemodialysis Patients With Secondary Hyperparathyroidism

Etelcalcetide shows promise for reducing parathyroid hormone in hemodialysis patients with secondary hyperparathyroidism.

Malignancy Risk & Vitamin D Deficiency: An Unclear Relationship

Malignancy Risk & Vitamin D Deficiency: An Unclear Relationship

According to the National Cancer Institute, there are not enough available data to establish whether taking vitamin D can prevent cancer.

Less Frequent Dosing of Bisphosphonate in Patients With Bone Metastases

Less Frequent Dosing of Bisphosphonate in Patients With Bone Metastases

Less frequent dosing with zoledronic acid does not increase fracture risk in patients with bone metastases.

Hip Fracture Risk in Type 2 Diabetes

Hip Fracture Risk in Type 2 Diabetes

The association between risk for hip fracture and diabetes was attenuated after accounting for mortality risk.

Long-Term DPP-4 Inhibitor Use Not Associated With Fracture Risk in Type 2 Diabetes

Long-Term DPP-4 Inhibitor Use Not Associated With Fracture Risk in Type 2 Diabetes

For patients with type 2 diabetes, long-term use of dipeptidyl peptidase-4 (DPP-4) inhibitors is not associated with fracture risk.

VIDEO: Clinical Trial Results for Abaloparatide

Lorraine Fitzpatrick, MD, discusses updated results from the ACTIVE phase 3 clinical trial.

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