Adrenal

Infants Hospitalized Most Often for Adrenal Insufficiency, Hypopituitarism

Infants Hospitalized Most Often for Adrenal Insufficiency, Hypopituitarism

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Rates of adrenal insufficiency and hypopituitarism were highest during infancy, particularly among females.

AAP Shares List of 5 Unnecessary Pediatric Tests and Procedures

AAP Shares List of 5 Unnecessary Pediatric Tests and Procedures

The American Academy of Pediatrics urges careful consideration between parents and clinicians prior to ordering these tests.

Pain Perception in Adrenal Insufficiency Not Affected by Hydrocortisone Dose

Pain Perception in Adrenal Insufficiency Not Affected by Hydrocortisone Dose

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Mechanical pain perception and somatosensory function in secondary adrenal insufficiency were examined.

Mild Cases of Cushing's Syndrome Present Diagnostic Challenges

Mild Cases of Cushing's Syndrome Present Diagnostic Challenges

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As a result of overlapping features with various other conditions, milder cases of Cushing's syndrome present diagnostic challenges and may require careful observation as well as biochemical and imaging tests.

Long-Term Testosterone Treatment Reduced HbA1c in Men With Hypogonadism and Type 2 Diabetes

Long-Term Testosterone Treatment Reduced HbA1c in Men With Hypogonadism and Type 2 Diabetes

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At 12 years of testosterone treatment, HbA1c decreased to 5.5±0.3%.

New Research Highlights Possible Genetic Cause of Cushing's Disease

New Research Highlights Possible Genetic Cause of Cushing's Disease

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The analysis led to the identification of 4 potentially pathogenic missense variants in CABLES1.

Severe Adrenal Deficiency With Topical Steroid Application for Psoriasis

Severe Adrenal Deficiency With Topical Steroid Application for Psoriasis

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The patient presented with symptoms consistent with adrenal deficiency following 18 years of topical steroid application.

Bone Mineral Density Changes Related to Adrenal Incidentalomas in Menopausal Women

Bone Mineral Density Changes Related to Adrenal Incidentalomas in Menopausal Women

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After 24 months, bone mineral density was statistically different from baseline.

Pediatric Endocrine Society Provides Guidance for Growth Hormone Use in Pediatric Patients

Pediatric Endocrine Society Provides Guidance for Growth Hormone Use in Pediatric Patients

The guidelines focused on idiopathic short stature, growth hormone deficiency, and primary IGF-I deficiency.

Growth Hormone Plus Aromatase Inhibitor in Congenital Adrenal Hyperplasia

Growth Hormone Plus Aromatase Inhibitor in Congenital Adrenal Hyperplasia

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A case report suggested that combination therapy with growth hormone and anastrozole may improve final height in congenital adrenal hyperplasia.

Study Identifies Major Risk Locus for Addison's Disease

Study Identifies Major Risk Locus for Addison's Disease

BACH2 is a major risk locus for Addison's disease, according to a study published in the Journal of Internal Medicine.

Higher Rate of Addison's Disease Seen in Patients Born in Winter Months

Higher Rate of Addison's Disease Seen in Patients Born in Winter Months

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In the United Kingdom, rates of the disease were highest for those born in December, while in Poland, rates were highest for those born in January.

Aldosterone Reduced With Losartan in Hypertension Without Obstructive Sleep Apnea

Aldosterone Reduced With Losartan in Hypertension Without Obstructive Sleep Apnea

For patients with hypertension and obstructive sleep apnea, treatment with losartan does not lead to significant reductions in aldosterone, but the treatment is tied to aldosterone reductions in patients with hypertension but without obstructive sleep apnea.

Diabetes Risk Higher With 'Nonfunctional' Adrenal Tumors

Diabetes Risk Higher With 'Nonfunctional' Adrenal Tumors

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Patients with nonfunctional adrenal tumors have a nearly 2-fold increased risk for diabetes.

Abnormal Adrenal Function May Affect Some Women With PCOS

Abnormal Adrenal Function May Affect Some Women With PCOS

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A portion of women with polycystic ovary syndrome may experience excess adrenal hormone production.

Left Adrenal Vein Aldosterone Ratio May Help Predict Right-Sided Unilateral Disease in Primary Aldosteronism

Left Adrenal Vein Aldosterone Ratio May Help Predict Right-Sided Unilateral Disease in Primary Aldosteronism

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A cutoff value less than 0.5 performed well for right-sided disease, but 5.5 cannot be used to reliably identify left-sided disease.

Mild Hypercortisolism Due to Adrenal Adenoma

Alice C. Levine, MD, discusses mild hypercortisolism due to adrenal incidentalomas.

Radiofrequency Ablation May Be Safe, Effective Treatment for Adrenal Neoplasms

Radiofrequency Ablation May Be Safe, Effective Treatment for Adrenal Neoplasms

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Researchers discuss a case in which a woman was successfully treated with radiofrequency ablation.

New Recommendations Intend to Increase Screening for Primary Aldosteronism

New Recommendations Intend to Increase Screening for Primary Aldosteronism

Updated recommendations from the Endocrine Society revise aldosteronism screening guidelines.

Hormone Insufficiencies May Be Prevalent After Blast Concussion in Veterans

Hormone Insufficiencies May Be Prevalent After Blast Concussion in Veterans

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Chronic hypopituitarism was noted in 44% of US veterans with mild traumatic brain injury.

Case Report Describes Cushing's Syndrome in Infant Treated With Ophthalmic Steroid

Case Report Describes Cushing's Syndrome in Infant Treated With Ophthalmic Steroid

Four-month-old developed iatrogenic Cushing's syndrome after 6 weeks of intranasal dexamethasone ophthalmic solution.

Addison's Disease: New Guideline Details Diagnosis and Treatment

Addison's Disease: New Guideline Details Diagnosis and Treatment

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The first-ever guideline from Endocrine Society on Addison's disease details specifics of diagnostic tests and glucocorticoid therapy.

Acute Ozone Exposure Increased Stress Hormone, Altered Lipid Metabolism

Acute Ozone Exposure Increased Stress Hormone, Altered Lipid Metabolism

Acute ozone exposure increases stress hormones and causes alterations in peripheral lipid metabolism in humans.

High-, Low-Dose ACTH Stimulation Tests Adequate for Ruling in Adrenal Insufficiency Diagnosis

High-, Low-Dose ACTH Stimulation Tests Adequate for Ruling in Adrenal Insufficiency Diagnosis

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Both high- and low-dose adrenocorticotropic hormone stimulation tests are adequate for including adrenal insufficiency as a diagnosis.

Primary Aldosteronism Screening Cost-Effective in Resistant Hypertension

Primary Aldosteronism Screening Cost-Effective in Resistant Hypertension

CT scanning followed by adrenal venous sampling was a cost-effective way to screen for primary aldosteronism.

Endocrine Society Releases Guidelines on Treatment of Cushing's Syndrome

Endocrine Society Releases Guidelines on Treatment of Cushing's Syndrome

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Guideline focuses on surgical resection to normalize cortisol levels.

Morning, Evening Cortisol Levels Linked to Brain Volume, Cognition in Older People

Morning, Evening Cortisol Levels Linked to Brain Volume, Cognition in Older People

Higher evening salivary cortisol levels tied to lower brain volume, worse cognitive function in older people.

Cortisol May Strengthen Frightening Memories

Cortisol May Strengthen Frightening Memories

The stress hormone may play a role in PTSD and anxiety.

Hormonal Evaluation of Adrenal Enlargement May Be Beneficial

Hormonal Evaluation of Adrenal Enlargement May Be Beneficial

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Because adrenal enlargement is more common in some patients, hormonal evaluation may be useful in determining its clinical relevance.

Adrenal Insufficiency Patients Require More Education on Adrenal Crisis

Adrenal Insufficiency Patients Require More Education on Adrenal Crisis

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Many patients with adrenal insufficiency do not receive adequate education on steroid dose adjustment or have emergency glucocorticoid kits.

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